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Devonian Advances Thykamine™ Patent Strategy with Proprietary Fingerprint and Robust Manufacturing Controls
Prnewswire· 2026-02-17 14:00
Core Insights - Devonian Health Group Inc. has filed a proprietary Thykamine™ fingerprint in recent patent applications, which is a key element of its long-term intellectual property strategy [1] - The Thykamine™ fingerprint identifies eight specific chemical components in precise ratios, validated through advanced HPLC-MS methods, showing 98% confidence in batch consistency [1] - The company emphasizes the quality and consistency of Thykamine™, which has demonstrated anti-inflammatory and anti-fibrotic properties in various studies, including a Phase IIa clinical study [1] Patent Strategy - The Thykamine™ fingerprint will be systematically included in all future patent filings related to Thykamine™ [1] - This strategy aims to strengthen the company's intellectual property portfolio and regulatory preparedness for pharmaceutical development [1] Manufacturing and Quality Control - HPLC-MS methodology has shown high reproducibility across manufactured batches, confirmed by NMR analysis [1] - Potency assays using a U-937 human cell-based model validated that each batch of Thykamine™ exhibits equivalent biological activity, consistently inhibiting key inflammatory cytokines [1] Product Overview - Thykamine™, developed from Devonian's SUPREX™ platform, targets health conditions related to inflammation and oxidative stress, including ulcerative colitis and atopic dermatitis [1] - The product's anti-inflammatory, anti-oxidative, and immunomodulatory properties have been supported by numerous in vitro and in vivo studies [1] Company Background - Devonian Health Group Inc. is a clinical-stage pharmaceutical company focused on developing drugs for autoimmune fibroinflammatory diseases [1] - The company also develops high-value cosmeceutical products and operates a commercialization subsidiary, Altius Healthcare LP, for selling prescription pharmaceuticals in Canada [1]
Devonian Health Group Announces Grant of Stock Options
Prnewswire· 2025-12-19 14:15
Core Viewpoint - Devonian Health Group Inc. has announced the grant of stock options to its directors, employees, and consultants as part of its compensation strategy, reflecting the company's ongoing commitment to incentivize key personnel in the biopharmaceutical sector focused on inflammatory diseases [1][2][3]. Stock Options Grant - The Board of Directors approved the granting of a total of 2,948,056 stock options, with 2,798,056 options allocated to directors at an exercise price of $0.18, valid for 10 years [2]. - Additionally, 385,950 stock options were granted to employees as performance bonuses, with a vesting schedule of 25% on the grant date and 25% per year for the next three years [3]. Product Development - Devonian's flagship product, Thykamine™, is designed for the prevention and treatment of inflammatory and oxidative stress-related health conditions, including ulcerative colitis and atopic dermatitis, supported by extensive clinical studies [4]. - The company operates under the SUPREX™ platform, which is patented in multiple regions, enhancing its competitive edge in the biopharmaceutical market [4]. Company Overview - Devonian Health Group Inc. is a clinical-stage pharmaceutical company established in 2015, focusing on innovative treatments for autoimmune inflammatory conditions [5][7]. - The company also develops high-value cosmeceutical products and has a subsidiary, Altius, dedicated to selling prescription pharmaceuticals in Canada [6].