Key Takeaways QGEN posted Q4 adjusted EPS of 62 cents, in line with estimates, while revenues rose 3.7% year over year.QIAGEN saw strength in Sample Technologies and Diagnostic Solutions, offset by a decline in PCR revenues.QGEN reported margin pressure, with adjusted operating margin falling 429 bps amid higher costs.QIAGEN N.V.’s (QGEN)  fourth-quarter 2025 adjusted earnings per share (EPS) were 62 cents, the same at the constant exchange rate (CER). The reported figure increased 1.6% on a year-over-year ...

Qiagen (NYSE:QGEN) Q4 2025 Earnings call February 05, 2026 09:30 AM ET Company ParticipantsDaniel Wendorff - VP and Head of Investor RelationsRoland Sackers - CFOThierry Bernard - CEOConference Call ParticipantsAisyah Noor - AnalystCasey Woodring - AnalystDan Brennan - AnalystDoug Schenkel - AnalystHarry Gillis - AnalystJack Meehan - AnalystKavya Deshpande - AnalystMichael Ryskin - AnalystOdysseas Manesiotis - AnalystTycho Peterson - AnalystOperatorLadies and gentlemen, thank you for standing by. I am Katie ...

Qiagen (QGEN) reported $540.42 million in revenue for the quarter ended December 2025, representing a year-over-year increase of 3.7%. EPS of $0.62 for the same period compares to $0.64 a year ago.The reported revenue represents a surprise of +2.36% over the Zacks Consensus Estimate of $527.96 million. With the consensus EPS estimate being $0.62, the EPS surprise was +0.83%.While investors scrutinize revenue and earnings changes year-over-year and how they compare with Wall Street expectations to determine ...

Core Insights - QIAGEN N.V. has set its 2026 priorities focused on product commercialization, regulatory milestones, and automation innovations, aiming for $2 billion in combined annual sales by 2028 [1][2] Group 1: Growth Pillars - The five growth pillars identified by QIAGEN include Sample technologies, QIAstat-Dx syndromic testing, QIAcuity digital PCR, QIAGEN Digital Insights (QDI) bioinformatics, and QuantiFERON for latent tuberculosis testing, all of which show significant growth potential [3][4] - QIAGEN plans to launch new products and submissions in 2026 to expand its market reach and enhance its automation systems, thereby increasing recurring revenues from consumables and software [2][4] Group 2: Sample Technologies - QIAGEN's acquisition of Parse Biosciences in December 2025 enhances its Sample technologies portfolio, particularly in single-cell analysis, with expected sales contribution of approximately $40 million in 2026 [4][5] - New sample preparation systems are set to launch in 2026, targeting applications such as liquid biopsy and microbiome research, which will help expand the installed base of instruments [6] Group 3: QIAstat-Dx and QIAcuity - QIAstat-Dx has exceeded 5,200 instrument placements globally by the end of 2025, with new blood culture identification panels submitted for regulatory clearance to enhance its testing menu [7] - QIAcuity digital PCR is set to expand its portfolio with new gene expression assays in 2026, further driving adoption in pharmaceutical applications [9][11] Group 4: QIAGEN Digital Insights (QDI) - QDI plans to introduce at least 14 AI-enabled software solutions by 2028, focusing on enhancing pharmaceutical R&D and clinical decision-making [12][13] - The integration of the Franklin platform with AI capabilities aims to improve genetic analysis and reporting in hereditary and oncology applications [14][15] Group 5: QuantiFERON - QIAGEN is developing a fifth generation of its QuantiFERON test, with updates planned for 2026 to meet increasing testing demands in tuberculosis diagnostics [16][17] - The new generation of chemistry for the LIAISON QuantiFERON-TB Gold Plus II assay is expected to enhance testing capacity and speed, allowing laboratories to test up to 75% more patients per hour [17][18]

Core Insights - Qiagen reported revenue of $532.58 million for Q3 2025, a year-over-year increase of 6.1%, with an EPS of $0.61 compared to $0.59 a year ago, exceeding the Zacks Consensus Estimate of $525.99 million by 1.25% [1] - The company delivered an EPS surprise of 5.17%, with the consensus EPS estimate being $0.58 [1] Financial Performance - Qiagen's stock has returned -2.7% over the past month, while the Zacks S&P 500 composite increased by 2.1% [3] - The stock currently holds a Zacks Rank 3 (Hold), indicating potential performance in line with the broader market [3] Sales by Product Groups - Diagnostic solutions - QIAstat-Dx: $32 million vs. $34.77 million estimated, +14.3% year-over-year [4] - Diagnostic solutions - QuantiFERON: $136 million vs. $133.3 million estimated, +11.5% year-over-year [4] - Diagnostic solutions - Other: $41 million vs. $39.24 million estimated, 0% year-over-year [4] - Other: $18 million vs. $17.37 million estimated, +28.6% year-over-year [4] - PCR / Nucleic acid amplification: $75 million vs. $76.5 million estimated, +1.4% year-over-year [4] - Genomics / NGS: $61 million vs. $60.62 million estimated, +10.9% year-over-year [4] - Diagnostic solutions total: $209 million vs. $207.61 million estimated, +6.1% year-over-year [4] - Sample technologies: $170 million vs. $163.77 million estimated, +4.9% year-over-year [4]

Core Insights - QIAGEN has announced a definitive agreement to fully acquire Parse Biosciences, enhancing its capabilities in single-cell research solutions [1] - This acquisition will significantly expand QIAGEN's Sample technologies portfolio into the rapidly growing single-cell sequencing market [1] - The technology from Parse Biosciences is designed to support research involving up to millions of cells, indicating a strong scalability potential [1]

Company Overview - Qiagen NV is a Netherlands-based holding company that provides "Sample to Insight" solutions, transforming biological samples into molecular insights through integrated sample and assay technologies, bioinformatics, and automation systems [1] - The company specializes in isolating and preparing DNA, RNA, and proteins from various biological materials, and its assay technologies enable the analysis of these biomolecules [1] - Qiagen operates primarily in two end markets: Molecular Diagnostics and Life Sciences, generating approximately 90% of its sales from recurring consumables revenue [4] Investment Context - Fivespan Partners has established a position in Qiagen and is engaging with its management to explore potential improvements [3][7] - Qiagen has struggled to create shareholder value post-Covid, with 1-, 3-, and 5-year returns of 1%, -6%, and 1%, respectively, while trading at around 13 times EV/EBITDA compared to peers at approximately 15 times [5] - The company has a strong market position and brand reputation but has lost focus on its core business, leading to missed opportunities for growth [6] Strategic Opportunities - Management is encouraged to invest more in its core business, improve communication with the market, and optimize its balance sheet to enhance shareholder value [6] - Qiagen's operating margin is currently at 25%, with potential for expansion to over 30% through a more disciplined approach [6] - The company holds $1.15 billion in cash and short-term investments against $1.39 billion in debt, suggesting room for leveraging to fund growth initiatives and share buybacks [6] Market Dynamics - Qiagen's dual-listing and geographical revenue distribution show that 52% of its FY24 sales are from North America, 32% from Europe, the Middle East, and Africa, and 16% from Asia [4] - The company has previously engaged in discussions for potential transactions, including a failed offer from Thermo Fisher Scientific at 43 euros per share, indicating its attractiveness as an acquisition target [8] - Fivespan's investment philosophy includes evaluating strategic transactions, and while it does not prioritize sales, it remains open to advocating for shareholder value in the event of acquisition offers [8]