Core Insights - Polen Capital's "Polen Focus Growth Strategy" reported a gross return of 3.34% and a net return of 3.14% for Q3 2025, underperforming the Russell 1000 Growth Index at 10.51% and the S&P 500 Index at 8.12% [1] - The equity market's strong performance was attributed to enthusiasm for generative AI and strength in the semiconductor sector, alongside positive economic surprises and better-than-expected corporate earnings [1] Company-Specific Insights - Thermo Fisher Scientific Inc. (NYSE:TMO) was highlighted as a key stock, with a one-month return of 9.12% but a 52-week loss of 12.65%, closing at $524.58 per share with a market capitalization of $198.088 billion on October 13, 2025 [2] - Polen Focus Growth Strategy eliminated its position in Thermo Fisher Scientific to fund the purchase of Uber, citing ongoing macro, policy, and funding headwinds that are expected to persist [3] - Thermo Fisher Scientific's revenue grew 3% to $10.85 billion in Q2, and it ranked 26th among the 30 most popular stocks among hedge funds, with 117 hedge fund portfolios holding its stock at the end of Q2 [4]

Core Insights - Douglas Lane & Associates has increased its investment in Thermo Fisher Scientific by purchasing 16,745 shares valued at approximately $7.79 million, bringing its total holdings to 216,276 shares [2][11] - Following this purchase, Thermo Fisher Scientific accounts for 1.5% of the fund's reportable assets under management as of September 30, 2025 [3] Company Overview - Thermo Fisher Scientific reported a total revenue of $43.21 billion and a net income of $6.58 billion for the trailing twelve months [4] - The company has a dividend yield of 0.32% and its stock price was $534.68 as of October 9, 2025, reflecting a 12% decline over the past year [3][4] Business Performance - Thermo Fisher achieved a 3% revenue growth to $10.9 billion in its fiscal second quarter, with a 6% year-over-year increase in diluted earnings per share (EPS) to $4.28 [13] - The company has raised its fiscal guidance for 2025 to approximately $44 billion in sales, up from $42.9 billion the previous year [14] Investment Rationale - The current price-to-earnings (P/E) ratio of Thermo Fisher is lower than it was a year ago, suggesting that the stock is more attractively valued now [12] - The combination of rising revenue, increasing EPS, and a reasonable P/E ratio positions Thermo Fisher stock as a compelling buy opportunity [14]

Market Overview - The stock market experienced significant volatility in Q2 2025, with the S&P 500 reaching an all-time high by the end of June [1] - The market saw a drop of 7% from April 2 to April 7 due to the liberation day tariff announcement, followed by a rebound of over 22% from the April 7 low through the end of June [1] - The Russell 1000 Growth returned 17.8% and the S&P 500 returned 10.9% in the quarter, with large caps significantly outperforming small caps and growth outperforming value [1] Renaissance Large Cap Growth Strategy Performance - The strategy outperformed the S&P 500 Index but underperformed the Russell 1000 Growth benchmark [1] Company Focus: Thermo Fisher Scientific Inc. - Thermo Fisher Scientific Inc. (NYSE:TMO) was highlighted as an underperformer, with a one-month return of -0.11% and a 52-week loss of 21.70% [2] - As of September 09, 2025, Thermo Fisher's stock closed at $487.65 per share, with a market capitalization of $182.859 billion [2] - The company reported solid operating results but saw a decline of 18.5% in its stock price, attributed to lowered full-year guidance due to tariff-related macro weakness and uncertainty regarding NIH funding delays impacting academic and government customers [3]