Core Insights - WuXi Biologics has achieved significant advancements in 2025 through its CRDMO model, enhancing its position as a preferred partner for biopharmaceutical innovators and multinational corporations [1][2] - The company reported a record high of 209 new integrated projects in 2025, bringing the total to 945, with approximately 50% of these projects originating from U.S. clients [2][8] - WuXi Biologics is focusing on complex modalities, particularly bispecific/multispecific antibodies and ADCs, which now account for nearly 50% of its total project pipeline [4][8] Project Development - The company added 23 new projects in 2025, including 6 Phase III and commercial projects, with a significant portion involving complex modalities [5] - Bispecific/multispecific antibodies and ADCs have seen a growth of approximately 30%, reaching 196 and 252 projects respectively, contributing nearly 20% of the company's revenue with over 120% year-over-year growth [4][8] Research and Innovation - WuXi Biologics' research services achieved record-breaking upfront payments and potential milestone values exceeding USD 4 billion in 2025, driven by T-cell engager deals [7] - The CD3 platform has been widely adopted in the industry, enhancing the efficacy-safety balance of bispecific antibodies [6][7] Manufacturing Capabilities - The total number of Phase III clinical and commercial manufacturing projects reached 99 in 2025, with a strong focus on operational excellence and technology leadership [11][12] - WuXi Biologics completed 28 PPQs in 2025, maintaining a success rate of over 99% and delivering more than 350 large-scale batches since 2017 [12][13] Global Expansion - The company is increasing strategic investments in the U.S. and has commenced construction of new facilities in Singapore, positioning these sites as strategic hubs within its global network [14][15] - An MOU was signed with the Qatar Free Zones Authority to establish a strategic site in Qatar, expanding WuXi Biologics' global footprint [16] Digital Innovations - WuXi Biologics has integrated digital innovations across its operations, achieving approximately 40% productivity gains and a 20% improvement in efficiency through smart manufacturing solutions [18] - The launch of the digital twin platform PatroLab aims to enhance process performance and ensure high-quality biologics manufacturing [18] Sustainability Efforts - The company has made significant strides in sustainability, earning an MSCI AAA Rating and being recognized in various sustainability indices [19][23] - WuXi Biologics is committed to driving green technology innovations and fostering positive social and environmental impacts [23] Future Outlook - In 2026, WuXi Biologics aims to build on its strong momentum with accelerated growth driven by robust research and manufacturing capabilities [20]