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NIH Stops Johnson & Johnson's Blood Thinner Drug Arm In Stroke Trial After Safety Review
Benzinga· 2026-02-11 19:23
The National Institutes of Health (NIH) on Tuesday discontinued the low-dose rivaroxaban arm of its ongoing Phase 3 CAPTIVA stroke prevention trial.The primary goal of the trial is to determine if the experimental arms (rivaroxaban or ticagrelor, or both) are superior to the clopidogrel arm for lowering the 1-year rate of ischemic stroke, intracerebral hemorrhage, or vascular death.The move follows an independent safety review that identified increased safety events and evidence that the treatment was unlik ...