transcranial magnetic stimulation (TMS)

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HOPE Therapeutics, Inc. a subsidiary of NRx Pharmaceuticals, Inc. (NASDAQ:NRXP) Announces Signing of Term Sheet for $7.8 Million Debt Financing to Fuel HOPE Clinic Acquisitions
Prnewswire· 2025-05-15 14:15
Core Insights - HOPE Therapeutics, Inc. has signed a term sheet with Universal Capital, LLC to secure $7.8 million in acquisition capital for expanding its network of interventional psychiatry clinics, aiming for a total of $10.3 million in acquisition capital through additional funding [1][8] Company Overview - HOPE Therapeutics is a subsidiary of NRx Pharmaceuticals, focused on establishing a network of clinics that provide neuroplastic treatments, including ketamine and transcranial magnetic stimulation (TMS), for severe depression and PTSD [2][6] - NRx Pharmaceuticals is a clinical-stage biopharmaceutical company developing therapeutics for central nervous system disorders, including NRX-101, which is designated as a Breakthrough Therapy by the FDA for suicidal treatment-resistant bipolar depression [7][9] Industry Context - Neuroplastic treatments are gaining recognition for their effectiveness in treating severe depression and PTSD, with clinical trials demonstrating their ability to foster new synaptic connections in the brain [2][3] - The U.S. Department of Veterans Affairs has highlighted the importance of psychedelic treatments, such as ketamine, in addressing veteran suicide, indicating a growing acceptance of these therapies in mainstream mental health care [3][4] Financial Strategy - The funding from Universal Capital is part of a broader strategy to acquire best-in-class clinics, with plans for future funding as additional assets are identified [4][8] - The company aims to address the mental health crisis in the U.S., where over 13 million Americans plan to commit suicide each year, emphasizing the urgent need for effective treatment options [4]
HOPE Therapeutics, Inc. and NRx Pharmaceuticals (NASDAQ:NRXP) Announce Signing of Definitive Agreement to Purchase Kadima Neuropsychiatry Institute; Foundational Acquisition for the HOPE Network of Interventional Psychiatry Clinics
Prnewswire· 2025-05-13 12:03
Core Insights - HOPE Therapeutics, Inc. has signed a definitive agreement to acquire Kadima Neuropsychiatry Institute, which will serve as a clinical model for HOPE's treatment offerings and continue its role in neuroplastic therapy research [1][4][6] - Kadima is recognized as a leading interventional psychiatry clinic in California, known for pioneering ketamine treatment for CNS disorders and is profitable with expected growth [2][6] - Dr. David Feifel, a prominent figure in interventional psychiatry, will join HOPE as Chief Medical Innovation Officer, enhancing the company's leadership in mental healthcare [3][6] Company Overview - NRx Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing therapeutics for CNS disorders, including suicidal bipolar depression and PTSD, with its investigational drug NRX-101 designated as a Breakthrough Therapy by the FDA [5][6] - HOPE Therapeutics aims to build a network of interventional psychiatry clinics offering treatments such as ketamine and TMS, supported by a digital therapeutic platform [8] Strategic Implications - The acquisition of Kadima is expected to be accretive to revenue and EBITDA for both NRx and HOPE, indicating a positive financial outlook post-acquisition [6] - The integration of Kadima's expertise and clinical model is aligned with HOPE's strategy to redefine mental healthcare access and delivery [4][6]
HOPE Therapeutics, Inc. and NRx Pharmaceuticals, Inc. (NASDAQ:NRXP) to Host Investor Event at Mar-A-Lago Club on May 8, 2025
Prnewswire· 2025-05-06 12:03
Core Viewpoint - HOPE Therapeutics, Inc. is hosting an investor event to discuss strategic initiatives and progress in their clinical pipeline, emphasizing their commitment to mental health innovation [1][2][4]. Company Overview - HOPE Therapeutics is a subsidiary of NRx Pharmaceuticals, focusing on building a network of interventional psychiatry clinics to provide innovative treatments for suicidal depression and related disorders [7]. - NRx Pharmaceuticals is a clinical-stage biopharmaceutical company developing therapeutics for central nervous system disorders, including suicidal bipolar depression and chronic pain [5]. Strategic Initiatives - The investor event will cover expansion plans for HOPE's network of clinics and updates on NRx's clinical pipeline [2][4]. - Recent acquisitions of HOPE clinics are aimed at scaling the interventional psychiatry network [8]. Clinical Developments - NRx is preparing to file a New Drug Application (NDA) for NRX-100 (IV ketamine) for treating suicidal depression, following a $4.3 million filing fee waiver from the FDA [6][8]. - NRX-101 has received Breakthrough Therapy Designation and is set for an NDA filing for Accelerated Approval in patients with bipolar depression and suicidality or akathisia [5][8]. Technological Integration - Plans include integrating digital health solutions, such as CRM-based technology and telepsychiatry, to enhance clinical operations across the HOPE network [8].