Charles River(US:CRL)2022-05-06 12:40Financial Performance - Revenue for 1Q22 was $913.9 million, a 10.8% increase year-over-year, with organic revenue growth of 9.4%[4] - GAAP Operating Margin was 16.3% in 1Q22, a 130 bps increase year-over-year[4] - Non-GAAP Operating Margin was 21.4% in 1Q22, a 70 bps increase year-over-year[4] - GAAP EPS was $1.81 in 1Q22, a 50.8% increase year-over-year[4] - Non-GAAP EPS was $2.75 in 1Q22, an 8.7% increase year-over-year[4] Segment Results - DSA (Discovery and Safety Assessment) revenue for 1Q22 was $544.3 million, an 8.6% increase year-over-year, with organic revenue growth of 9.5%[29] - RMS (Research Models and Services) revenue for 1Q22 was $176.5 million, a 0.2% decrease year-over-year, but organic revenue growth of 8.7%[44] - Manufacturing revenue for 1Q22 was $193.1 million, a 31.8% increase year-over-year, with organic revenue growth of 10.1%[58] Guidance - The company updated its 2022 revenue growth guidance to 13.5%-15.5% reported and 12.5%-14.5% organic[24] - The company maintained its 2022 Non-GAAP EPS guidance at $11.50-$11.75[24] - Adjusted net interest expense is expected to be $98 million-$102 million in 2022[83] DSA Backlog - DSA backlog was $2.8 billion at the end of 1Q22, a greater than 75% year-over-year increase and greater than 15% increase since year-end 2021[31]