Financial Data and Key Metrics Changes - Total revenue for the full year of 2024 was 37.7million,a336.7 million in 2023, with adjusted growth of 11% when excluding a large clinical solutions order from 2023 [9][25] - Free cash outflow improved from 26.7millionin2023to13.5 million in 2024, significantly better than initial guidance of 18million[11][24]−Netlossforthefullyearof2024was26.7 million or 0.57perdilutedshare,comparedtoanetlossof36.8 million or 1.16perdilutedsharein2023[34]BusinessLineDataandKeyMetricsChanges−Revenuefromcatalogreagents,whichrepresentedapproximately607.1 million for the full year of 2024, a 5% increase from 6.7millionin2023,witha7633.4 million in 2024 from 45.9millionin2023,drivenbyreducedheadcountandspending[33]−Capitalexpendituresfor2024were1.1 million, a decrease from 7.9millionin2023,indicatingafocusoncostmanagement[35]−Thecompanyhasamendeditscreditfacility,extendingthematuritydatetoMarch2030andincreasingliquidityby4 million [42][43] Q&A Session Summary Question: Observations on customer behavior and budget changes - Management noted a recent softening in customer orders, particularly among smaller biotech firms, with some customers delaying orders from Q1 to Q2 [51][52] Question: Composition of new customer pipeline - Most new customers are in preclinical or phase one stages, with successful conversions from phase two customers possible [56] Question: Any large one-time orders expected in 2025 - Management indicated no significant one-time orders are anticipated for 2024, but acknowledged potential revenue lumpiness due to customer order variability [58][61] Question: Updated number of cell and gene therapy customers - The company now supports over 100 total cell and gene therapy customers, with 27% of total revenue derived from this segment [66] Question: Revenue phasing for 2025 - The first quarter of 2025 is expected to be the lowest, with a gradual increase in revenue through Q2 and Q3, followed by a potential decrease in Q4 due to fewer business days [70][71] Question: Revenue ramp for new clinical customers - It typically takes about a year to a year and a half for new clinical customers to reach spending levels comparable to more mature customers [79] Question: Pricing changes for reagents - The company implemented mid-single-digit price increases for its products at the beginning of the year [82]