Lilly(US:LLY)2025-05-01 11:22Financial Performance - Total revenue reached $12.7 billion, a 45% increase compared to Q1 2024[11] - Key product revenue surged to $7.5 billion, representing a 119% growth rate[11] - Non-GAAP earnings per share (EPS) increased by 29% to $3.34[11] - The company reaffirms its 2025 revenue guidance of $58.0 billion to $61.0 billion[9] Market Leadership and Expansion - The company gained U.S. incretin analogs market leadership with a 53.3% market share in total prescriptions[9] - Mounjaro U.S. type 2 diabetes incretin analogs TRx share of market (SOM) reached 39% and NBRx SOM 46% at the end of Q1 2025[22] - Zepbound U.S. branded anti-obesity TRx SOM exceeded 60% and NBRx SOM 74% at the end of Q1 2025[22] Strategic Investments and Pipeline Development - The company announced plans to double U.S. manufacturing investments, committing a total of $50 billion since 2020[9] - Research & Development investment reached $2.7 billion, accounting for 8% growth[11] - The company disclosed positive Phase 3 trial results for oral GLP-1, orforglipron, demonstrating statistically significant efficacy and a safety profile consistent with injectable GLP-1 medicines[9] - Jaypirca achieved Q1 2025 sales of $92 million and secured regulatory approval in the EU for relapsed or refractory CLL patients previously treated with a BTK inhibitor[22]