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众生药业(002317) - 2025年6月9日投资者关系活动记录表

Group 1: Company Overview and R&D Pipeline - Guangdong Zhongsheng Pharmaceutical Co., Ltd. has established a multi-modal and healthy R&D ecosystem focusing on metabolic diseases and respiratory diseases, with two innovative drug projects approved for market and several in clinical trials [1] - The innovative drug ZSP1601 for treating metabolic dysfunction-related fatty liver disease (MASH) has completed Phase Ib/IIa clinical trials, showing significant reduction in liver inflammation markers [3][15] - The oral antiviral drug Lurivon (brand name: Le Ru Ling®) received conditional approval in March 2023 and is included in the national medical insurance directory, providing affordable treatment options for patients [3] Group 2: Clinical Trial Results - ZSP1601 has shown potential in improving liver inflammation and fibrosis, with results published in Nature Communications [3][15] - The clinical trial for Lurivon demonstrated effectiveness and safety, particularly for elderly and patients with liver and kidney dysfunction, without requiring dosage adjustments [3] - The innovative drug Anglave (brand name: An Rui Wei®) has shown statistically significant improvement in flu symptom relief compared to placebo, with a median symptom relief time of 38.83 hours [4][8] Group 3: Financial and Asset Management - In 2024, the company recorded an asset impairment loss of CNY 546.68 million, impacting the net profit attributable to shareholders by CNY 484.10 million [12] - The company has made provisions for inventory and goodwill impairment losses totaling CNY 201.68 million due to market conditions and policy impacts [12][14] Group 4: Strategic Initiatives and Future Plans - The company plans to enhance its marketing strategy by integrating academic resources and building a network of experts in respiratory and infectious diseases [11] - The company has increased its stake in its subsidiary Zhongsheng Ruichuang to 74.26%, enhancing control over its operations and R&D capabilities [27] - A change in the use of raised funds has been proposed to accelerate the R&D of innovative drugs, specifically RAY1225 injection and Anglave granules [28][30]