凯莱英医药集团（天津）股份有限公司 董事会薪酬与考核委员会规则 （2023 年 12 月修订） | 第一章 | 总则 2 | | --- | --- | | 第二章 | 人员组成 2 | | 第三章 | 职责权限 3 | | 第四章 | 决策程序 4 | | 第五章 | 议事规则 5 | | 第六章 | 附则 6 | 第一章 总则 第一条 为建立健全凯莱英医药集团（天津）股份有限公司（以下简称"公 司"）董事及高级管理人员的薪酬和考核管理制度，建立科学、规范的激励机制 和约束机制，进一步完善公司法人治理结构，根据《中华人民共和国公司法》、 《上市公司治理准则》、《香港联合交易所有限公司证券上市规则》（以下简称 "《香港上市规则》"）和《凯莱英医药集团（天津）股份有限公司章程》（以 下简称"《公司章程》"）等有关规定，制定本规则。 第二条 董事会薪酬与考核委员会是董事会按照《公司章程》设立的董事会 专门工作机构，主要负责研究制定和审查董事及高级管理人员的薪酬政策与方案； 负责研究董事及高级管理人员的考核标准，并进行考核。 第三条 本规则所称高级管理人员是指首席执行官（CEO）、联席首席执行 官（Co-CEO）、 ...

证券代码：002821 证券简称：凯莱英 公告编号：2023-065 凯莱英医药集团（天津）股份有限公司 关于签署募集资金三方监管协议的公告 本公司及全体董事会成员保证公告内容真实、准确和完整，不存 在虚假记载、误导性陈述或重大遗漏。 一、募集资金基本情况 经中国证券监督管理委员会《关于核准凯莱英医药集团（天津）股份有限公 司非公开发行股票的批复》（证监许可[2020] 1912号）的核准，凯莱英医药集团 （天津）股份有限公司（以下简称"公司"）非公开发行人民币普通股股票（A股） 10,178,731.00股，每股面值1元，发行价格为227.00元/股，募集资金总额人民币 2,310,571,937.00元，扣除与发行有关的费用人民币35,611,280.94元，公司实际募 集资金净额为人民币2,274,960,656.06元。截至2020年9月23日止，上述募集资金 已全部到账，已经容诚会计师事务所（特殊普通合伙）审验 ，出具了容诚验字 [2020]100Z0073号验资报告。 公司于2023年10月30日召开第四届董事会第四十二次会议和第四届监事会 第三十三次会议，审议通过了《关于部分募集资金投资项目变更 ...

发及改进工艺路线、提升研发效率与成功率、降低研发成本； 在药物商业化供应阶段，公司通过不断的工艺优化持续降低生 产成本，提高生产效率，保障产品质量和供应的稳定性，同时 制药公司亦可以极大节省固定资产投资，将更多资源投放在研 发环节。 证券代码：002821 证券简称：凯莱英 凯莱英医药集团（天津）股份有限公司 投资者关系活动记录表 编号：2023-007 投资者关系活动 类别 □特定对象调研 □分析师会议 □媒体采访 □业绩说明会 □新闻发布会 √路演活动 □现场参观 □其他 （请文字说明其他活动内容） 参与单位名称及 人员姓名 网络端和现场参会的投资者及相关方 时间 2023 年 10 月 31 日 15：00-17：00 地点 北京市海淀区丹棱街 1 号互联网金融中心 408 上市公司接待人 员姓名 高级副总裁兼董事会秘书 徐向科先生 投资者关系活动 主要内容介绍 一、 企业介绍 凯莱英是一家全球领先、技术驱动型的医药外包一站式 综合服务商。通过为国内外制药公司、生物技术公司提供药品 全生命周期的一站式服务，高效和高质量产品以及服务可加快 创新药的临床研究与商业化应用，并降低创新药的研发和生产 成本。公司 ...

Financial Performance - In the first nine months of 2023, the company achieved operating revenue of CNY 6.383 billion, a year-on-year decrease of 18.29% [3] - Net profit attributable to shareholders was CNY 2.210 billion, down 18.77% year-on-year, primarily due to large orders delivered in the same period last year [3] - Excluding the impact of large orders, operating revenue increased by 24.51% year-on-year [3] - Gross margin for the first nine months was 54.1%, an increase of 7.2 percentage points year-on-year, attributed to favorable exchange rates and strict cost control [3] Business Strategy - The company aims to deepen relationships with major clients, expand into small and medium-sized clients, and grow in European and Japanese markets while focusing on cost control and efficiency [3] - The small molecule business, excluding large orders, grew by 25.45% year-on-year, with revenue from multinational pharmaceutical companies increasing by 66.51% [3] Capital Expenditure - Capital expenditure for the first three quarters was CNY 825 million, with an expected total not exceeding CNY 1.5 billion for the year, focusing more on emerging businesses [4] Market Demand and Trends - The company reported a high capacity utilization rate in Q4, indicating a saturated state [4] - Demand from multinational pharmaceutical companies for outsourcing R&D and production remains strong, with orders continuing to materialize [5] - The domestic market's revenue growth has slowed due to capital environment impacts, with no clear turning point observed yet [5] Future Outlook - The company anticipates that gross margins will align with historical averages in the future, supported by operational improvements and cost reduction measures [4] - The company plans to increase solid-phase synthesis capacity to 10,000L in the first half of next year to meet commercial production needs [4] - The company is actively expanding its presence in the U.S. and Japanese markets, with positive developments noted in 2022 [6]

Financial Overview - Total revenue for Q1-Q3 2023 reached 6.383 billion RMB, a decrease of 18.3% compared to 7.811 billion RMB in Q1-Q3 2022 [4] - Net profit attributable to shareholders was 2.210 billion RMB, down from 2.721 billion RMB in the previous year [26] - Adjusted net profit for the same period was 2.193 billion RMB, compared to 2.317 billion RMB in 2022 [26] Profitability Metrics - Gross margin for Q1-Q3 2023 was 54.1%, an increase of 7.2% from the previous year [4] - Net profit margin was 34.4%, reflecting a slight decrease of 0.2% year-on-year [4] - Adjusted net profit margin improved to 34.6%, up by 4.7% compared to 29.7% in 2022 [26] Cash Flow and Operational Performance - Cash flow from operating activities was 2.864 billion RMB, showing a 0.9% increase [4] - Excluding large orders, revenue from small molecule CDMO business grew by 66.5% year-on-year [10] Adjustments and Financial Metrics - The company provided adjusted financial metrics to better reflect operational performance, excluding non-recurring items [4] - Adjusted net profit and adjusted net profit margin are considered beneficial for understanding the company's core performance [4] Balance Sheet Highlights - Total assets as of Q3 2023 amounted to 19.764 billion RMB, up from 18.239 billion RMB in 2022 [33] - Total liabilities were reported at 2.292 billion RMB, a decrease from 2.544 billion RMB in the previous year [37] - Shareholders' equity increased to 17.472 billion RMB from 15.695 billion RMB in 2022 [37]

Financial Performance - The company's revenue for Q3 2023 was ¥1,761,546,766.74, a decrease of 36.41% compared to the same period last year[6]. - Net profit attributable to shareholders was ¥523,736,701.20, down 46.60% year-on-year[6]. - The total revenue for the first nine months of 2023 reached ¥6,383,057,146.18, reflecting an 18.29% decline year-on-year, but a 24.51% increase when excluding large orders[8]. - The small molecule CDMO business generated revenue of ¥5,565,000,000, a decrease of 22.01% year-on-year, but a 25.45% increase when excluding large orders[8]. - Emerging business revenue was ¥813,000,000, showing a year-on-year growth of 21.05%[8]. - Total operating revenue for Q3 2023 was CNY 6,383,057,146.18, a decrease of 18.3% compared to CNY 7,811,575,256.14 in the same period last year[22]. - Net profit for Q3 2023 was CNY 2,200,808,678.45, a decline of 19.1% compared to CNY 2,720,936,643.42 in Q3 2022[23]. Assets and Liabilities - The company's total assets increased to ¥19,764,226,099.24, an 8.36% rise from the end of the previous year[6]. - The company reported a total asset increase to CNY 19,764,226,099.24 as of September 30, 2023, up from CNY 18,239,273,651.93 at the beginning of the year[21]. - Current assets rose to CNY 13,059,172,427.71, an increase of 10.1% from CNY 11,860,458,372.35[20]. - The total liabilities decreased to CNY 2,292,382,441.40 from CNY 2,544,270,867.15, a reduction of 9.9%[21]. Earnings and Shareholder Information - Basic earnings per share for Q3 2023 were ¥1.45, down 43.84% compared to the same period last year[6]. - Basic and diluted earnings per share were both CNY 6.1, down from CNY 7.46 and CNY 7.43 respectively in the previous period[24]. - The total number of ordinary shareholders at the end of the reporting period was 50,563, with no preferred shareholders[15]. - The largest shareholder, ASYMCHEM LABORATORIES, holds 31.15% of the shares, totaling 115,133,168 shares[16]. Cash Flow and Investments - Cash flow from operating activities for the first nine months was ¥2,864,254,599.72, a slight increase of 0.90%[6]. - Cash received from operating activities rose by 303.43% to ¥172,736,270.48, primarily due to an increase in government subsidies related to capital[13]. - Cash inflow from investment activities totaled approximately CNY 20.10 billion, significantly higher than CNY 2.40 billion in the previous period[27]. - Cash outflow from investment activities was approximately CNY 21.00 billion, compared to CNY 5.08 billion in the previous period, resulting in a net cash flow from investment activities of approximately -CNY 895 million[27]. - The company received CNY 136.30 million in investment income, a recovery from a loss of CNY 4.38 million in the previous period[25]. Expenses and Costs - For the first nine months of 2023, the company's tax and additional charges increased by 59.61% to ¥59,382,485.19 compared to ¥37,204,484.78 in the same period of 2022, primarily due to additional taxes from export tax rebates[13]. - Sales expenses rose by 44.38% to ¥138,989,428.90, driven by continued market expansion and investments in the sales team and marketing activities[13]. - Cash outflow for purchasing goods and services decreased by 56.70% to ¥1,570,814,104.79, reflecting a reduction in large-scale raw material purchases compared to the previous year[13]. - Research and development expenses for Q3 2023 were CNY 513,114,161.26, an increase of 16.1% compared to CNY 442,204,004.98 in Q3 2022[22]. Other Financial Metrics - The weighted average return on equity was 3.18%, a decrease of 3.19% year-on-year[6]. - The total comprehensive income for the period was approximately CNY 2.21 billion, a decrease from CNY 2.75 billion in the previous period[24]. - The company’s capital reserve decreased to CNY 9,634,892,679.05 from CNY 10,143,534,669.29, a decline of 5.0%[21]. - The company’s deferred income tax assets increased to CNY 252,904,157.45 from CNY 177,857,982.20, a growth of 42.1%[20].

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或因依 賴該等內容而引致之任何損失承擔任何責任。 Asymchem Laboratories (Tianjin) Co., Ltd. 凱萊英醫藥集團（天津）股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：6821) 二零二三年第三季度報告 本公告乃由凱萊英醫藥集團（天津）股份有限公司（「公司」或「本公司」，連同其 附屬公司「本集團」）根據香港聯合交易所有限公司證券上市規則（「上市規則」）第 13.09條及第13.10B條以及證券及期貨條例（香港法例第571章）第XIVA部項下的 內幕消息條文（定義見上市規則）而作出。 茲載列本公司在深圳證券交易所網站刊發的《凱萊英醫藥集團（天津）股份有限公 司二零二三年第三季度報告》，僅供參閱。本公司二零二三年第三季度報告（「二 零二三年第三季度報告」）以中、英文雙語編製。如兩個版本有任何不相符之處， 應以中文版本為準。 本公司董事（「董事」）會（「董事會」）提醒本公司股東及潛在投資者，本公告所載 ...

凯莱英医药集团（天津）股份有限公司 独立董事意见 关于部分募集资金投资项目变更实施主体的独立意见 本次部分募集资金投资项目变更实施主体事项可以进一步优化公司管理和 业务架构，符合公司发展战略及公司与全体股东的共同利益；决策程序符合《深 圳证券交易所上市公司自律监管指引第 1 号—主板上市公司规范运作》、《上市公 司监管指引第 2 号—上市公司募集资金管理和使用的监管要求》等相关法律法 规、规范性文件规定，不存在损害公司和公司全体股东特别是中小股东利益的情 形。与会独立董事同意该事项。 二〇二三年十月三十一日 凯莱英医药集团（天津）股份有限公司独立董事 关于第四届董事会第四十二次会议相关事项的独立意见 根据《深圳证券交易所股票上市规则（2023 年 8 月修订）》、《上市公司独立 董事管理办法》、《深圳证券交易所上市公司自律监管指引第 1 号——主板上市公 司规范运作》、《公司章程》及《独立董事工作制度》等有关规定，我们作为凯莱 英医药集团（天津）股份有限公司(以下简称"公司")的独立董事，认真审阅了 公司的相关文件，基于独立判断，对本次董事会审议的议案发表意见如下： 独立董事： 孙雪娇 王青松 李家聪 ...

经中国证券监督管理委员会证监许可[2020]1912 号文《关于核准凯莱英医药 集团（天津）股份有限公司非公开发行股票的批复》核准，公司于 2020 年 9 月 向特定投资者发行人民币普通股（A 股）股票 10,178,731.00 股，每股发行价为 227.00 元/股，募集资金总额为人民币 2,310,571,937.00 元，扣除券商承销费用（不 含税）32,696,772.70 元，公司实际收到募集资金人民币 2,277,875,164.30 元，扣 除 其 他 发 行 费 用 人 民 币 2,914,508.24 元 ， 实 际 募 集 资 金 净 额 人 民 币 2,274,960,656.06 元。上述资金到账情况业经容诚会计师事务所（特殊普通合伙） 出具容诚验字[2020]100Z0073 号《验资报告》验证。公司对募集资金采取了专户 存储管理。 第一创业证券承销保荐有限责任公司 关于凯莱英医药集团（天津）股份有限公司 部分募集资金投资项目变更实施主体的核查意见 第一创业证券承销保荐有限责任公司（以下简称"一创投行"或"保荐机构"） 作为凯莱英医药集团（天津）股份有限公司（以下简称"凯莱英"或 ...

证券代码：002821 证券简称：凯莱英 公告编号：2023-061 凯莱英医药集团（天津）股份有限公司 第四届董事会第四十二次会议决议的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 一、董事会会议召开情况 凯莱英医药集团（天津）股份有限公司（以下简称"公司"）第四届董事会 第四十二次会议通知于 2023 年 10 月 16 日以电子邮件及书面等形式发送给各位 董事、监事及高级管理人员，会议于 2023 年 10 月 30 日以通讯方式召开。公司 应到董事 9 名，实到董事 9 名，公司监事及高级管理人员列席了本次会议。会议 由公司董事长 HAO HONG 先生召集，会议的召集和召开符合《公司法》及相关法 律、法规以及《公司章程》的有关规定。 二、董事会议案审议情况 会议采用通讯方式进行表决，经全体与会董事审议，通过了如下决议： 1、审议通过了《2023 年第三季度报告》 会议同意该项议案。 表决结果：同意 9 票，反对 0 票，弃权 0 票。 公司根据中国证监会及深圳证券交易所有关规定，编制的 2023 年第三季度 报告真实反映了报告期内公司的运营情 ...