Core Viewpoint - The market anticipates Beam Therapeutics Inc. (BEAM) to report a year-over-year increase in earnings despite lower revenues for the quarter ending September 2025, with actual results being crucial for stock price movement [1][2]. Earnings Expectations - Beam Therapeutics is expected to report a quarterly loss of $0.98 per share, reflecting a year-over-year change of +16.2%, while revenues are projected to be $12.99 million, down 9% from the previous year [3]. - The consensus EPS estimate has been revised 5.19% higher in the last 30 days, indicating a reassessment by analysts [4]. Earnings Surprise Prediction - The Zacks Earnings ESP model suggests that the Most Accurate Estimate for Beam Therapeutics is lower than the Zacks Consensus Estimate, resulting in an Earnings ESP of -9.41%, indicating bearish sentiment among analysts [12]. - Despite the negative Earnings ESP, the stock holds a Zacks Rank of 2, complicating predictions of an earnings beat [12]. Historical Performance - In the last reported quarter, Beam Therapeutics was expected to post a loss of $1.04 per share but delivered a loss of -$1.00, resulting in a surprise of +3.85% [13]. - Over the past four quarters, the company has beaten consensus EPS estimates two times [14]. Industry Comparison - In the Zacks Medical - Biomedical and Genetics industry, Sarepta Therapeutics (SRPT) is expected to post a loss of $0.03 per share for the same quarter, indicating a year-over-year change of -104.8%, with revenues expected to be $346.23 million, down 25.9% [18]. - Sarepta's consensus EPS estimate has been revised 13.1% higher in the last 30 days, resulting in a positive Earnings ESP of +1,733.32%, suggesting a likely earnings beat [19][20].

Core Insights - Premarket trading is showing notable activity with significant price movements indicating potential trading opportunities before the market opens [1] Premarket Gainers - Click Holdings Limited (CLIK) is up 81% at $11.17 [3] - Avidity Biosciences, Inc. (RNA) is up 43% at $70.72 [3] - Dyne Therapeutics, Inc. (DYN) is up 37% at $23.58 [3] - Zenas BioPharma, Inc. (ZBIO) is up 21% at $29.00 [3] - ProPetro Holding Corp. (PUMP) is up 18% at $7.47 [3] - PepGen Inc. (PEPG) is up 17% at $5.35 [3] - Unusual Machines, Inc. (UMAC) is up 15% at $14.85 [3] - Semler Scientific, Inc. (SMLR) is up 14% at $27.32 [3] - ETHZilla Corporation (ETHZ) is up 13% at $20.51 [3] - Relmada Therapeutics, Inc. (RLMD) is up 13% at $2.38 [3] Premarket Losers - Smart Logistics Global Limited (SLGB) is down 37% at $3.21 [4] - MaxsMaking Inc. (MAMK) is down 22% at $4.08 [4] - Prenetics Global Limited (PRE) is down 14% at $14.40 [4] - United States Antimony Corporation (UAMY) is down 14% at $10.22 [4] - NeurAxis, Inc. (NRXS) is down 12% at $3.01 [4] - Obook Holdings Inc. (OWLS) is down 9% at $11.39 [4] - Qualigen Therapeutics, Inc. (QLGN) is down 9% at $3.30 [4] - Critical Metals Corp. (CRML) is down 8% at $13.70 [4] - Neuphoria Therapeutics Inc. (NEUP) is down 8% at $5.73 [4] - Beam Therapeutics Inc. (BEAM) is down 7% at $25.86 [4]

Core Insights - Beam Therapeutics Inc. is a precision-genetics firm specializing in base editing, focusing on one-time ex vivo and in vivo treatments for hematology and liver genetic diseases [1] Company Overview - Beam Therapeutics is pioneering innovative genetic therapies aimed at providing durable and potentially functional cures for specific genetic disorders [1] Research and Development Focus - The company is dedicated to developing advanced treatments that could significantly impact the management of hematological and liver-related genetic diseases [1]

Core Insights - Beam Therapeutics Inc. is a precision-genetics firm specializing in base editing, focusing on one-time ex vivo and in vivo treatments for hematology and liver genetic diseases [1] Company Overview - Beam Therapeutics is pioneering innovative genetic therapies aimed at providing durable and potentially functional cures for specific genetic disorders [1] Research and Development Focus - The company is dedicated to developing advanced treatments that could significantly impact the management of hematology and liver-related genetic diseases [1]

Core Viewpoint - Beam Therapeutics Inc. (BEAM) is showing potential for a bullish breakout following a "golden cross" technical pattern, indicating a favorable investment opportunity [1][2]. Technical Analysis - BEAM's 50-day simple moving average has crossed above its 200-day simple moving average, forming a "golden cross," which is a significant bullish indicator in trading [1][2]. - The golden cross pattern typically involves three stages: a downtrend that bottoms out, a crossover of the shorter moving average over the longer one, and a subsequent upward price movement [3]. Performance Metrics - Over the past four weeks, BEAM has experienced a price increase of 6.8%, suggesting positive momentum [4]. - The company currently holds a 2 (Buy) rating on the Zacks Rank, further supporting the bullish outlook [4]. Earnings Outlook - There has been one upward revision in earnings estimates for BEAM in the last 60 days, with no downward revisions, indicating a positive earnings outlook for the current quarter [4]. - The Zacks Consensus Estimate for BEAM has also increased, reinforcing the bullish sentiment [4][5]. Investment Consideration - The combination of favorable earnings estimate revisions and the recent technical breakout suggests that investors should monitor BEAM for potential gains in the near future [5].

Core Viewpoint - Beam Therapeutics Inc. (BEAM) has seen a 2.8% increase in share price over the past four weeks, closing at $25.79, with a potential upside of 76.2% based on Wall Street analysts' mean price target of $45.43 [1] Price Targets - The average of 14 short-term price targets ranges from a low of $20.00 to a high of $80.00, with a standard deviation of $18.14, indicating variability among analysts [2] - The lowest estimate suggests a decline of 22.5% from the current price, while the highest estimate indicates a potential upside of 210.2% [2] Analyst Consensus and Earnings Estimates - Analysts show strong agreement in revising earnings estimates higher, which historically correlates with stock price movements [4][11] - Over the last 30 days, one estimate has increased, leading to a 2.9% rise in the Zacks Consensus Estimate for the current year [12] Zacks Rank - BEAM holds a Zacks Rank 2 (Buy), placing it in the top 20% of over 4,000 ranked stocks based on earnings estimate factors, suggesting a solid potential upside [13] Conclusion on Price Targets - While the consensus price target may not be a reliable indicator of the extent of potential gains, it does provide a directional guide for price movement [14]

Group 1 - Beam Therapeutics Inc. (BEAM) has shown a year-to-date performance increase of approximately 4%, outperforming the average gain of 0.4% in the Medical sector [4] - The Zacks Consensus Estimate for BEAM's full-year earnings has risen by 1.4% over the past quarter, indicating improved analyst sentiment and earnings outlook [4] - Beam Therapeutics Inc. holds a Zacks Rank of 2 (Buy), suggesting it has characteristics favorable for outperforming the market in the near term [3] Group 2 - Beam Therapeutics Inc. is part of the Medical - Biomedical and Genetics industry, which has an average gain of 8.9% year-to-date, indicating that BEAM is slightly underperforming its industry [6] - Humana (HUM) is another Medical stock that has outperformed the sector with a year-to-date increase of 5.4% and also holds a Zacks Rank of 2 (Buy) [5] - The Medical group consists of 956 companies and is currently ranked 5 in the Zacks Sector Rank, reflecting a strong overall performance [2]

Group 1: Affirm Holdings, Inc. - Jim Cramer recommended buying Affirm Holdings, Inc. (NASDAQ:AFRM) after Rothschild & Co analyst Harry Bartlett upgraded the stock from Neutral to Buy and raised the price target from $74 to $101 [1][1] - Affirm shares rose 1% to settle at $76.65 on Tuesday [7] Group 2: Beam Therapeutics Inc. - Cramer expressed skepticism about Beam Therapeutics Inc. (NASDAQ:BEAM), stating "I can't go with" regarding the stock [1] - Beam Therapeutics announced on Aug. 14 that the FDA granted regenerative medicine advanced therapy designation status for Beam-101 [1] - Beam shares declined 2.9% to settle at $25.13 on Tuesday [7] Group 3: Crown Castle Inc. - Cramer criticized the business model of Crown Castle Inc. (NYSE:CCI) as "not a sound one" [2] - RBC Capital analyst Jonathan Atkin upgraded Crown Castle from Sector Perform to Outperform but lowered the price target from $113 to $112 [2] - Crown Castle shares gained 1.2% to settle at $95.14 [7] Group 4: Shopify Inc. - Cramer stated that Shopify Inc. (NASDAQ:SHOP) is going "much higher," supported by TD Securities raising its price target from $130 to $156 [2] - Shopify shares fell 2% to close at $161.28 on Tuesday [7] Group 5: CoreWeave, Inc. - Cramer described CoreWeave, Inc. (NASDAQ:CRWV) as "good" [2] - CoreWeave announced plans to acquire Monolith AI, a UK-based pioneer in applying machine learning to complex physics and engineering problems [2] - CoreWeave shares fell 3.8% to settle at $128.83 [7] Group 6: CrowdStrike Holdings, Inc. - Cramer expressed confidence in CrowdStrike Holdings, Inc. (NASDAQ:CRWD) and its CEO George Kurtz, expecting the stock to rise [3] - Wells Fargo analyst Andrew Nowinski maintained an Overweight rating on CrowdStrike and raised the price target from $550 to $600 [3] - CrowdStrike shares fell 2.3% to close at $484.62 [7]

Group 1: Affirm Holdings, Inc. - Jim Cramer recommended buying Affirm Holdings, Inc. (NASDAQ:AFRM) after Rothschild & Co analyst Harry Bartlett upgraded the stock from Neutral to Buy and raised the price target from $74 to $101 [1][1] - Affirm shares rose 1% to settle at $76.65 on Tuesday [7] Group 2: Beam Therapeutics Inc. - Cramer expressed skepticism about Beam Therapeutics Inc. (NASDAQ:BEAM), stating "I can't go with" the stock [1] - Beam Therapeutics announced on Aug. 14 that the FDA granted regenerative medicine advanced therapy designation status for Beam-101 [1] - Beam shares declined 2.9% to settle at $25.13 on Tuesday [7] Group 3: Crown Castle Inc. - Cramer criticized the business model of Crown Castle Inc. (NYSE:CCI), calling it "not a sound one" [2] - RBC Capital analyst Jonathan Atkin upgraded Crown Castle from Sector Perform to Outperform but lowered the price target from $113 to $112 [2] - Crown Castle shares gained 1.2% to settle at $95.14 [7] Group 4: Shopify Inc. - Cramer stated that Shopify Inc. (NASDAQ:SHOP) is going "much higher," supported by TD Securities raising its price target from $130 to $156 [2] - Shopify shares fell 2% to close at $161.28 on Tuesday [7] Group 5: CoreWeave, Inc. - Cramer described CoreWeave, Inc. (NASDAQ:CRWV) as "good" [2] - CoreWeave announced plans to acquire Monolith AI, a UK-based pioneer in applying machine learning to complex physics and engineering problems [2] - CoreWeave shares fell 3.8% to settle at $128.83 [7] Group 6: CrowdStrike Holdings, Inc. - Cramer expressed confidence in CrowdStrike Holdings, Inc. (NASDAQ:CRWD) and its CEO George Kurtz, expecting the stock to rise [3] - Wells Fargo analyst Andrew Nowinski maintained an Overweight rating on CrowdStrike and raised the price target from $550 to $600 [3] - CrowdStrike shares fell 2.3% to close at $484.62 [7]

Core Viewpoint - Beam Therapeutics Inc. is recognized as a high-potential biotech stock, with analysts maintaining positive ratings and price targets reflecting confidence in the company's growth prospects [1][2]. Group 1: Analyst Ratings and Price Targets - H.C. Wainwright analyst Patrick Trucchio reiterated a Buy rating on Beam Therapeutics with a price target of $80 as of September 15 [1]. - BMO Capital analyst Kostas Biliouris also maintained a Buy rating, setting a price target of $40.00 [2]. Group 2: Company Strengths and Market Position - The optimistic ratings are supported by Beam Therapeutics' strong momentum in its in vivo and ex vivo base editing programs [2]. - The company has made significant technological advancements and holds a strong position in the alpha-1 antitrypsin deficiency (AATD) market, with management expressing confidence in the competitive positioning of its lead program, BEAM-302 [3][4]. Group 3: Product Focus and Development - Beam Therapeutics develops precision genetic medicines through base editing technology, targeting specific genomic sequences [4]. - The company's lead programs focus on treating sickle cell disease and alpha-1 antitrypsin deficiency, while also advancing initiatives in other genetic diseases, oncology, and immunology [5].