• Muscle fat infiltration (MFI): Measure of muscle health motion Tissue infiltration contributes to the loss of function by altering biomechanical properties 0% • MFF is an indicator of FSHD-affected muscles with a strong correlation to clinical function / disability Illustrative Normal-Appearing Intermediate End-stage Arjomand J, et al. Facioscapulohumeral muscular dystrophy (FSHD) voice of the patient report. Published November 5, 2020. Accessed March 1, 2021 8 10 p38α/β ON Losmapimod, a Highly Selective ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Exact name of registrant as specified in its charter) Delaware 47-4839948 (State or other jurisdiction of incorporation or organization) 26 Landsdowne Street Cambridge, Massachusetts 02139 (Address of principal executive offices) (Zip Code) (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION ...

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Q1 2023 Earnings Conference Call May 15, 2023 8:00 AM ET Company Participants Chris Calabrese - LifeSci Advisors, LLC Robert J. Gould - President and CEO Iain Fraser - Interim Chief Medical Officer Conference Call Participants Edward Tenthoff - Piper Sandler Joseph Schwartz - SVB Securities Unidentified Analyst - Goldman Sachs Matthew Biegler - Oppenheimer Judah Frommer - Crédit Suisse Operator Good morning and welcome to the Fulcrum Therapeutics First Quarter 2023 F ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 | Title of each class | Trading Symbol(s) | Name of each exchange on which registered | | --- | --- | --- | | Common stock, par value $0.001 per share | FULC | The Nasdaq Global Market | or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Fo ...

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Q4 2022 Earnings Conference Call March 9, 2023 8:00 AM ET Company Participants Chris Calabrese - LifeSci Advisors, LLC Robert Gould - Interim Chief Executive Officer Esther Rajavelu - Chief Financial Officer Alan Ezekowitz - Board Member Conference Call Participants Matthew Harrison - Morgan Stanley Matthew Biegler - Oppenheimer Judah Frommer - Credit Suisse Dae Gon Ha - Stifel Edward Tenthoff - Piper Sandler Joseph Schwartz - SVB Securities Tazeen Ahmad - BofA S ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-38978 FULCRUM THERAPEUTICS, INC. (Exact name of registrant as specified in its Charter) | Delaware | 47-4839948 | | --- | --- | | (St ...

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Q3 2022 Results Conference Call November 8, 2022 8:00 AM ET Company Participants Stephanie Ascher - Stern Investor Relations Bryan Stuart - President and Chief Executive Officer Esther Rajavelu - CFO Paul Bruno - Senior Vice President, Corporate Development Conference Call Participants Dae Gon Ha - Stifel Judah Frommer - Credit Suisse Matt Biegler - Oppenheimer Joseph Schwartz - SVB Leerink Operator Good morning, and welcome to Fulcrum Therapeutics Third Quarter 2022 ...

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Q2 2022 Earnings Conference Call August 11, 2022 8:00 AM ET Company Participants Stephanie Ascher - Stern, Investor Relations Bryan Stuart - President & Chief Executive Officer Judy Dunn - President, Research & Development Esther Rajavelu - Chief Financial Officer Paul Bruno - Executive Director, Corporate Development Conference Call Participants Judah Frommer - Credit Suisse Ted Tenthoff - Piper Sandler Dae Gon Ha - Stifel Matt Biegler - Oppenheimer Joseph Schwartz ...

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Q1 2022 Earnings Conference Call May 9, 2022 8:00 AM ET Company Participants Naomi Aoki - SVP, Corporate Communications & IR Bryan Stuart - President & CEO Judy Dunn - President, R&D Esther Rajavelu - CFO Chris Morabito - CMO Paul Bruno - Executive Director, Corporate Development Conference Call Participants Judah Frommer - Credit Suisse Dae Gon Ha - Stifel Ted Tenthoff - Piper Sandler Joseph Schwartz - SVB Matt Biegler - Oppenheimer Operator Good morning and welcome ...

Fulcrum Therapeutics March 2022 Disclaimer and Notice | --- | --- | |----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ...