CytoMed Therapeutics (GDTC)

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CytoMed makes cash bid for potential acquisition of TC BioPharm Limited’s relevant assets
Globenewswire· 2025-10-14 12:00
SINGAPORE, Oct. 14, 2025 (GLOBE NEWSWIRE) -- CytoMed Therapeutics Limited (NASDAQ: GDTC) (“CytoMed” or “Company”), a Singapore-based clinical stage biopharmaceutical company focused on harnessing its proprietary technologies to develop novel affordable donor-derived cell-based immunotherapies for the treatment of a broad range of cancers, including both blood and solid tumours, today announced that it has submitted a cash bid for an undisclosed sum with Michael Magnay and Rob Croxen of Alvarez and Marsal Eu ...
CytoMed Therapeutics Limited (GDTC) Q2 2025 Earnings Call Prepared Remarks Transcript
Seeking Alpha· 2025-10-02 16:02
Core Insights - The company reported a 100% increase in revenue to SGD 156,000 for the six months ended June 30, 2025 [2] - A net loss of $2.05 million was recorded, which could be reduced to $1.44 million when excluding certain costs [2] - Cash and bank balances stood at $2.86 million as of June 30, 2025, with a net tangible asset (NTA) of $7.15 million [2] Financial Performance Overview - Revenue for the first half of 2025 was generated from private banking services after acquiring the necessary license and assets [3] - Other operating income decreased by 8.5% year-on-year [2] - Loss per share was reported at $0.19 for the six months ended June 30, 2025 [2]
CytoMed Therapeutics (GDTC) - 2025 H1 - Earnings Call Transcript
2025-10-02 15:00
Financial Performance - Revenue increased by 100% to $156,000 for the six months ended June 30, 2025, compared to the same period in 2024 [3] - Other operating income decreased by 8.5% year on year, from $422,000 in H1 2024 to $386,000 in H1 2025 [5] - Net loss reported was $2,050,000 in 2025, which could be reduced to $1,440,000 when excluding certain costs [3][7] - Loss per share was $0.19 for the six months ended June 30, 2025 [4] - Cash and bank balances decreased from $4,970,000 as of December 31, 2024, to $2,860,000 as of June 30, 2025 [7] Business Line Performance - Revenue of $156,000 was generated from private banking services after acquiring a license and certain assets under IPSE depository in Malaysia [4] - Research expenses increased by 19.3% from $974,000 in H1 2024 to $1,160,000 in H1 2025, driven by higher employee benefits and clinical trial expenses [6] Market Data - The company reported a net loss in currency exchange of $402,000 and a net loss of $227,000 in fair value changes on warrant liability [5] - As of June 30, 2025, there were 72,371 warrants outstanding, with fair value changes of $76,000 recorded in the profit and loss account [8] Company Strategy and Industry Competition - The company is focusing on clinical trials and collaborations, with ongoing projects including CTM and iPSC GDNKT [9][10] - A new ATM agreement was signed with Levity to raise up to $4.3 million, indicating a strategy to enhance funding [11] - The corporate banking business is being rebranded as Longevity Bank, reflecting a strategic shift [11] Management Commentary on Operating Environment and Future Outlook - Management highlighted the completion of dose level one in a clinical trial and plans to complete Phase one trials in 2026 [9] - The company aims to apply for GDT trials in Malaysia and other locations, indicating a focus on expanding its market presence [10] Other Important Information - The company’s manufacturing facility has been audited by the Ministry of Health of Malaysia, ensuring compliance and operational readiness [11] Q&A Session Summary - The earnings call concluded without any questions from participants, indicating a lack of immediate inquiries regarding the financial performance or strategic direction [12]
CytoMed Therapeutics Announces Publication of Collaborative Research with The University of Texas, MD Anderson Cancer Center, Demonstrating the Potential of Allogeneic γδ T Cells in Acute Myeloid Leukemia
Globenewswire· 2025-10-02 11:00
Core Insights - CytoMed Therapeutics Limited has published a preclinical study indicating the potential of its allogeneic γδ T cell therapy (CTM-GDT) for treating acute myeloid leukemia (AML) [1][2] - The study was conducted in collaboration with The University of Texas, MD Anderson Cancer Center, under a research agreement established in May 2023 [1] - The findings support further clinical studies of allogeneic donor-derived γδ T cells for AML and other cancers, with plans to advance their next γδ T cell-based product into clinical trials [2] Company Overview - CytoMed, incorporated in 2018, is a clinical stage biopharmaceutical company focused on developing novel donor-derived cell-based immunotherapies for various cancers [3] - The company utilizes proprietary technologies, including gamma delta T cells and iPSC-derived gamma delta Natural Killer T cells, inspired by the success of CAR-T therapies in hematological malignancies [3] - CytoMed aims to provide innovative immunotherapy options for patients with limited treatment alternatives, particularly in Southeast Asia [3]
CytoMed Therapeutics (GDTC) - 2025 Q2 - Quarterly Report
2025-09-30 11:00
Exhibit 99.1 CYTOMED THERAPEUTICS LIMITED AND SUBSIDIARIES UNAUDITED INTERIM CONDENSED CONSOLIDATED FINANCIAL STATEMENTS INDEX | Page | | | --- | --- | | Unaudited Interim Condensed Consolidated Statements of Profit or Loss and Other Comprehensive Loss for the Six months | | | ended June 30, 2024 and 2025 | 1 | | Unaudited Interim Condensed Consolidated Statements of Financial Positions as of December 31, 2024 and June 30, 2025 | 2 | | Unaudited Interim Condensed Consolidated Statements of Cash Flows for th ...
Update on recent acquisition - CytoMed Therapeutics expands into auto-immune diseases building on its recent cord blood bank acquisition
Globenewswire· 2025-08-28 13:00
Core Insights - CytoMed Therapeutics Limited has successfully expanded clinical-scale natural killer (NK) cells from cord blood units that have been cryopreserved for over a decade, paving the way for new revenue streams and growth opportunities [1] - The company is reorganizing to create a new cord blood-derived biotech under LongevityBank Pte Ltd, which will focus on autologous therapies while CytoMed will concentrate on allogeneic therapies [2][3] - The acquisition of a licensed cord blood bank in Malaysia provides access to valuable cord blood for developing therapeutics for autoimmune diseases and cancers [4] Company Strategy - LongevityBank will leverage personalized cellular banking services for autologous therapies, while CytoMed will focus on donor blood-derived allogeneic therapies, which have ongoing clinical trials in Singapore and India [3] - The company plans to restart its cord blood banking business with new services, including immune cell banking, supported by resources from CytoMed [5] - Management intends to invest up to US$500,000 in LongevityBank to enhance laboratory capabilities and expedite research and development [5] Market Opportunity - The spinoff of LongevityBank is seen as a strategic move to manufacture cord blood-derived NK cells, which are being researched for their potential in treating autoimmune diseases [6] - The rising incidence of autoimmune diseases and increasing acceptance of personalized therapies present a favorable market environment for the company's offerings [7] - The cord blood bank acquisition is expected to positively impact the group's revenue, with better-than-anticipated performance [7]
CytoMed Therapeutics Limited Announces At-the-Market (ATM) Offering Program
GlobeNewswire· 2025-08-19 01:00
Core Viewpoint - CytoMed Therapeutics Limited has entered into an At-the-Market Sales Agreement to raise up to $4,304,945 through the sale of ordinary shares, which will be used for general corporate purposes and potential acquisitions [1][2][3] Group 1: Company Overview - CytoMed Therapeutics Limited is a clinical stage biopharmaceutical company based in Singapore, focused on developing novel donor blood-derived, cell-based allogeneic therapies for treating blood and solid cancers [1][4] - The company was incorporated in 2018 and spun off from Singapore's Agency for Science, Technology and Research (A*STAR) [4] - CytoMed utilizes proprietary technologies, including gamma delta T cells and iPSC-derived gamma delta Natural Killer T cells, to create immunotherapies inspired by the success of CAR-T therapies [4] Group 2: Financial Activities - The company has entered into a Sales Agreement with R.F. Lafferty & Co., Inc. to sell shares at its discretion based on market conditions and capital requirements [2] - Proceeds from the ATM program will be allocated for general corporate purposes, including business diversification, development initiatives, and capital expenditures [3] - The company has seen approximately 2,500 new customer sign-ups for its newly acquired cord blood bank since August 2024, contributing to revenue in 2025 [3]
Update On Clinical Trial Milestone - CytoMed Therapeutics Achieves Completion of Dose Level 1 of its ANGELICA TRIAL, and Proceeding to Dose Level 2 in Patients with Advanced Solid Tumors or Haematological Malignancies
Globenewswire· 2025-07-21 14:01
Core Insights - CytoMed Therapeutics Limited has successfully completed dose level 1 of its first-in-human Phase I dose-escalation clinical trial (ANGELICA Trial) for late-stage cancer patients and plans to start dose level 2 in Q3 2025 [1][2] - The ANGELICA Trial is focused on evaluating the safety and tolerability of allogeneic NKG2DL-targeting CAR gamma delta T cells (CTM-N2D) for various cancer indications, including advanced solid and hematological malignancies [2] - CTM-N2D utilizes gamma delta T cells from healthy donors, which can be infused into patients without the need for donor-patient compatibility matching, differentiating it from conventional CAR-αβ T cell therapies [3][4] Company Overview - CytoMed was incorporated in 2018 and spun off from Singapore's Agency for Science, Technology and Research (A*STAR), focusing on developing novel cell-based allogeneic immunotherapies for cancer treatment [5] - The company aims to address the clinical limitations and commercial challenges of existing CAR-T therapies, particularly in treating solid tumors [5]
CytoMed Therapeutics (GDTC) - 2024 Q4 - Annual Report
2025-04-28 21:00
[Full Year 2024 Financial Results and Corporate Updates](index=1&type=section&id=CytoMed%20Therapeutics%20Reports%20Full%20Year%20Ended%20December%2031%2C%202024%20Financial%20Results%20and%20Provides%20Clinical%20and%20Corporate%20Updates) [Financial Results](index=1&type=section&id=Financial%20Results%20for%20the%20full-year%20ended%20December%2031%2C%202024) For FY2024, CytoMed reported a 39% reduction in net loss to $1.85 million due to lower IPO-related expenses, with topline income increasing to $624,771, research expenses rising to $1.40 million, and cash balances at $3.64 million deemed sufficient through 2026 Key Financial Highlights (FY 2024 vs. FY 2023) | Financial Metric | FY 2024 | FY 2023 | Change | | :--- | :--- | :--- | :--- | | Topline Income | US$624,771 | US$588,423 | +6.2% | | Net Loss | US$1.85 million | US$3.03 million | -39% | | Research Expenses | US$1.40 million | US$1.16 million | +20.7% | | Other Expenses | US$730,532 | US$1.62 million | -54.9% | | Cash and Bank Balances | US$3.64 million | US$6.58 million | -44.7% | - The **significant reduction in net loss** was primarily due to the absence of initial public offering (IPO) related expenses, as well as lower company insurance and investor relations costs[4](index=4&type=chunk)[8](index=8&type=chunk) - The company believes its existing cash and bank balances of **US$3.64 million** will be sufficient to fund operations **through at least 2026**[5](index=5&type=chunk) - The **increase in research expenses** was mainly attributable to higher clinical trial expenses and increased employee benefits[6](index=6&type=chunk) [Clinical Updates](index=2&type=section&id=Clinical%20Updates) CytoMed has advanced its clinical pipeline, becoming a clinical-stage company by dosing the first patient in its Phase I ANGELICA trial in Singapore for its allogeneic gamma delta T cells, while also preparing for a Phase II trial in India, exploring opportunities in Malaysia, and advancing preclinical work with MD Anderson in the US for an eventual FDA IND submission - Became a **clinical-stage company** with the **first patient dosed** in the **Phase I ANGELICA trial** in Singapore in **November 2024**, marking a first-in-human trial using the company's patented donor-derived allogeneic gamma delta T cells[9](index=9&type=chunk) - An Indian partner received approval for a **Phase II Investigator Initiated Trial (IIT)**, with patient recruitment anticipated to commence in the **second half of 2025**[10](index=10&type=chunk) - US research collaborator, **MD Anderson**, has reported encouraging **in-vivo animal data** for Acute Myeloid Leukemia, with the goal of submitting an **Investigational New Drug (IND) application** to the **U.S. FDA**[12](index=12&type=chunk) - Finalizing the dossier for a **Phase I clinical trial** using umbilical cord-derived stem cells to treat osteoarthritis, with submission targeted for the **second half of 2025**[14](index=14&type=chunk) [Corporate Updates](index=3&type=section&id=Corporate%20Updates) The company is actively expanding its strategic footprint, exploring a joint venture in China for low-cost cell manufacturing and focusing on China and India as key markets, with a significant corporate development being the acquisition of a licensed cord blood bank in Malaysia in August 2024, which will supply raw materials for new therapeutic programs and is planned for a future spin-off - Exploring a **joint venture in China** to establish **low-cost cell manufacturing capabilities**, with **China and India** being strategic focus markets[15](index=15&type=chunk) - On **August 15, 2024**, the company completed the **acquisition of a licensed cord blood bank in Malaysia**, one of only three in the country[16](index=16&type=chunk) - The acquired cord blood bank will provide **cost-free raw materials** for strategic expansion into **cord blood-derived therapeutics** for auto-immune diseases and cancers[16](index=16&type=chunk) - The company intends to **spin off this cord blood subsidiary** in the future as a separate biopharmaceutical company[16](index=16&type=chunk) [Strategies for Growth](index=3&type=section&id=Strategies%20for%20Growth) For 2025, CytoMed's growth strategy focuses on achieving key clinical milestones, including the initial readout from the ANGELICA trial and submitting a U.S. FDA IND application, while also enhancing its U.S. presence by opening a liaison office in New York and pursuing new revenue streams through compassionate use programs and partnerships - An important **2025 milestone** is the **initial clinical readout of the ANGELICA trial**, anticipated by the **end of the year**[17](index=17&type=chunk) - Plans to submit a **U.S. FDA IND application** for its donor-derived allogeneic gamma delta T cells for a common form of leukemia[17](index=17&type=chunk) - Intends to establish a **liaison office in New York** to enhance its U.S. profile, be closer to investors, and seek **M&A or strategic alliance opportunities**[17](index=17&type=chunk) - Plans to implement **alternative revenue-generating methods in 2025**, such as **compassionate use programs** for no-option late-stage patients[18](index=18&type=chunk) - While having a **cash runway into 2026**, the company plans to **strengthen its financials in 2025** to capitalize on new opportunities, including **M&A**[19](index=19&type=chunk)
CytoMed Therapeutics (GDTC) - 2024 Q4 - Annual Report
2025-04-28 20:50
[PART I](index=15&type=section&id=PART%20I) [ITEM 3. KEY INFORMATION](index=15&type=section&id=ITEM%203.%20KEY%20INFORMATION) This section details the significant financial, business, manufacturing, and intellectual property risks facing the company [Risk Factors](index=15&type=section&id=D.%20Risk%20Factors) The company faces substantial risks from its limited operating history, unproven products, and reliance on licensed IP - The company is a clinical-stage biopharmaceutical firm with **no products approved for commercial sale** and has a limited operating history since its incorporation in 2018[35](index=35&type=chunk) Accumulated Losses (2022-2024) | Fiscal Year End | Accumulated Losses (S$) | | :--- | :--- | | Dec 31, 2022 | S$8.20 million | | Dec 31, 2023 | S$12.33 million | | Dec 31, 2024 | S$14.85 million | - The success of the business is highly dependent on its four main product candidates: **CTM-N2D, iPSC-gdNKT, CTM-GDT, and CTM-MSC**, none of which are guaranteed to receive regulatory approval or be successfully commercialized[51](index=51&type=chunk)[64](index=64&type=chunk) - The company relies heavily on **intellectual property licensed from third parties**, particularly ATPL (a subsidiary of A*STAR), and termination of these licenses could halt product development[142](index=142&type=chunk)[171](index=171&type=chunk) - As a Singapore-incorporated and **"controlled company"** under Nasdaq rules, shareholders may face difficulty protecting their interests and the company is exempt from certain governance requirements[269](index=269&type=chunk)[299](index=299&type=chunk) [ITEM 4. INFORMATION ON THE COMPANY](index=73&type=section&id=ITEM%204.%20INFORMATION%20ON%20THE%20COMPANY) This section provides an overview of the company's history, business strategy, product pipeline, and assets [History and Development of the Company](index=73&type=section&id=A.%20History%20and%20Development%20of%20the%20Company) The company was incorporated in Singapore in 2018 and executed a reverse stock split before its 2023 public listing - The company was incorporated in Singapore on March 9, 2018, and conducts its main business activities through its Malaysian subsidiaries, CytoMed Malaysia and IPSC Depository[331](index=331&type=chunk)[332](index=332&type=chunk) - A **1-for-380.83 reverse stock split** was effected on January 17, 2023, prior to its public listing[333](index=333&type=chunk) [Business Overview](index=74&type=section&id=B.%20Business%20Overview) The company is a clinical-stage biopharmaceutical firm developing "off-the-shelf" allogeneic cell-based immunotherapies - The company focuses on developing **"off-the-shelf" allogeneic cell therapies** to address the limitations of personalized, patient-specific (autologous) CAR-T treatments[338](index=338&type=chunk)[351](index=351&type=chunk) Product Pipeline Status | Product Candidate | Indication | Stage of Development | | :--- | :--- | :--- | | **CTM-N2D** | Relapsed/Refractory Solid Tumors | Phase I Clinical Trial (ANGELICA) | | **iPSC-gdNKT** | Relapsed/Refractory Solid Tumors | Preclinical Process Development | | **CTM-GDT** | Relapsed/Refractory Solid Tumors | Preclinical / IND Application planned | | **CTM-MSC** | Cartilage Injuries | Preclinical / Phase I planned | - The lead product, **CTM-N2D**, is being evaluated in the ANGELICA Phase I trial in Singapore, with two patients successfully dosed as of the report date[340](index=340&type=chunk)[377](index=377&type=chunk) - The company operates its own **cGMP facility in Johor, Malaysia**, which supports the manufacturing of cell therapy products for clinical trials and has been audited by the NPRA[349](index=349&type=chunk)[357](index=357&type=chunk) - In late 2024, the company acquired assets of a Malaysian cord blood bank, including a license, cryopreservation equipment with over **12,000 cord blood units**, and real estate[347](index=347&type=chunk) [Organizational Structure](index=141&type=section&id=C.%20Organizational%20Structure) The company is a Singapore-based holding company with its primary business activities conducted through Malaysian subsidiaries - The company is a holding company incorporated in Singapore, with its main operations conducted through its Malaysian subsidiaries, **CytoMed Malaysia and IPSC Depository**[664](index=664&type=chunk) [Property, Plants and Equipment](index=141&type=section&id=D.%20Property%2C%20Plants%20and%20Equipment) Key properties include a Singapore research lab, a Malaysian cGMP facility, and a newly acquired cord blood bank - The company owns a leasehold interest in its Singapore office and research lab, which expires in **2038**[473](index=473&type=chunk) - It owns a freehold, three-story **cGMP facility in Johor, Malaysia**, with approximately 8,600 square feet of gross floor area[480](index=480&type=chunk)[482](index=482&type=chunk) - Through a subsidiary, the company acquired two freehold properties in Malaysia housing a **cord blood bank facility** in late 2024[485](index=485&type=chunk) [ITEM 5. OPERATING AND FINANCIAL REVIEW AND PROSPECTS](index=141&type=section&id=ITEM%205.%20OPERATING%20AND%20FINANCIAL%20REVIEW%20AND%20PROSPECTS) Management analyzes the company's financial condition, operating results, and liquidity for fiscal years 2022-2024 [Operating Results](index=141&type=section&id=A.%20Operating%20Results) The company recorded its first revenue in 2024 but continues to incur net losses driven by R&D expenses - The company generated its first revenue of **S$69,501 in FY 2024**, derived from its newly acquired private blood banking services[677](index=677&type=chunk) Key Financial Results (S$) | Metric | 2022 | 2023 | 2024 | | :--- | :--- | :--- | :--- | | **Revenue** | - | - | 69,501 | | **Research Expenses** | (1,522,765) | (1,589,693) | (1,909,519) | | **Other Expenses** | (494,675) | (2,213,142) | (998,054) | | **Loss for the year** | (3,131,452) | (4,133,170) | (2,521,861) | - Research expenses increased by S$319,826 in 2024, primarily due to a **S$348,169 increase in clinical trial expenses** for the ANGELICA Trial[685](index=685&type=chunk) - Other expenses decreased by S$1.22 million in 2024, mainly because of the absence of **S$758,563 in IPO-related expenses** that were incurred in 2023[691](index=691&type=chunk) [Liquidity and Capital Resources](index=148&type=section&id=B.%20Liquidity%20and%20Capital%20Resources) Operations are funded by private equity and IPO proceeds, with future financing needed as clinical programs advance Cash and Cash Equivalents (S$) | As of | Cash and Bank Balances | | :--- | :--- | | Dec 31, 2023 | S$9.00 million | | Dec 31, 2024 | S$4.97 million | Summary of Cash Flows (S$) | Cash Flow Activity | 2022 | 2023 | 2024 | | :--- | :--- | :--- | :--- | | **Net cash used in operating activities** | (1,398,409) | (3,531,196) | (2,709,929) | | **Net cash (used in)/from investing activities** | (473,305) | (2,730,809) | 1,126,541 | | **Net cash from/(used in) financing activities** | 968,716 | 10,919,885 | (64,892) | - The company received net proceeds of **S$10.31 million** from its Initial Public Offering in April 2023[672](index=672&type=chunk) [Directors, Senior Management and Employees](index=153&type=section&id=ITEM%206.%20DIRECTORS%2C%20SENIOR%20MANAGEMENT%20AND%20EMPLOYEES) This section provides information on the company's leadership team, compensation practices, and employee base [Directors and Senior Management](index=153&type=section&id=A.%20Directors%20and%20Senior%20Management) The leadership includes a six-member Board with four independent directors and a five-person senior management team - The Board of Directors consists of 6 members: Chairman CHOO Chee Kong, Dr. ZENG Jieming, and four independent directors (Prof. LOH Yuin Han, Dr. YEW Chak Hua, Mark LEONG Kei Wei, Dr. TOH Keng Kiat)[732](index=732&type=chunk)[759](index=759&type=chunk) - The executive management team includes CHOO Chee Kong (Chairman), Dr. ZENG Jieming (CSO & Medical Officer), Dr. Lucas LUK Tien Wee (Chief Clinical Officer), GOH Yvonne (CFO), and TAN Yoong Ying (Chief Corporate Officer)[736](index=736&type=chunk) [Compensation](index=158&type=section&id=B.%20Compensation) This subsection details compensation for Named Executive Officers and non-employee directors for fiscal year 2024 2024 Named Executive Officer Compensation | Name and Principal Position | Total Compensation (U.S.$) | | :--- | :--- | | CHOO Chee Kong, Chairman | 38,143 | | Dr. ZENG Jieming, Chief Scientific and Medical Officer | 102,037 | | Dr. TAN Wee Kiat, Co-CEO and COO (resigned Dec 31, 2024) | 107,434 | - Non-employee directors receive annual cash retainers for their service on the board (**U.S.$12,000**) and its committees, with additional retainers for chairpersons[757](index=757&type=chunk) - The company adopted an **Executive Compensation Recovery (Clawback) Policy** on November 16, 2023, as required by Nasdaq listing standards[758](index=758&type=chunk) [Board Practices](index=160&type=section&id=C.%20Board%20Practices) The Board has four independent directors and three key committees: Audit, Compensation, and Nominating/Governance - The Board has three key committees: **Audit, Compensation, and Nominating and Corporate Governance**, all established on April 18, 2023[759](index=759&type=chunk) - The Audit Committee is chaired by Mark LEONG Kei Wei, who is designated as the **"audit committee financial expert"**[760](index=760&type=chunk) [Employees](index=162&type=section&id=D.%20Employees) As of the report date, the company has 43 full-time employees and maintains an equity incentive plan - The company has **43 full-time employees**, with 28 dedicated to R&D and manufacturing[771](index=771&type=chunk) - The 2023 Equity Incentive Plan reserves **1,279,117 ordinary shares** for awards such as share options and restricted shares to employees, directors, and consultants[775](index=775&type=chunk)[776](index=776&type=chunk) [Major Shareholders and Related Party Transactions](index=165&type=section&id=ITEM%207.%20MAJOR%20SHAREHOLDERS%20AND%20RELATED%20PARTY%20TRANSACTIONS) This section discloses the company's ownership structure and details material transactions with related entities [Major Shareholders](index=165&type=section&id=A.%20Major%20Shareholders) Ownership is concentrated, with Glorious Finance Limited holding 32.70% and directors/NEOs holding 28.28% as a group Major Shareholders (5% or more) | Shareholder | Ownership Percentage | | :--- | :--- | | Glorious Finance Limited | 32.70% | | mDR Limited | 10.59% | | WANG Shu | 7.66% | | 28 Consultants Limited | 6.20% | | ZENG Jieming | 5.11% | - All directors and NEOs as a group beneficially own **28.28%** of the company's ordinary shares[794](index=794&type=chunk) [Related Party Transactions](index=166&type=section&id=B.%20Related%20Party%20Transactions) The company engaged in transactions with its 20%-owned associate, Landmark Medical Centre Sdn Bhd (LMC) - The company holds a **20% equity stake** in Landmark Medical Centre Sdn Bhd (LMC), a private hospital in Malaysia[797](index=797&type=chunk) Research Income from LMC (S$) | Year | Research Income | | :--- | :--- | | 2022 | 207,206 | | 2023 | 183,518 | | 2024 | 115,277 | [Financial Information](index=168&type=section&id=ITEM%208.%20FINANCIAL%20INFORMATION) This section confirms no significant legal proceedings and outlines the company's policy of retaining earnings for expansion - The company has not been subject to any **significant legal or arbitration proceedings**[806](index=806&type=chunk) - The company **does not anticipate paying dividends** in the near future, intending to retain any earnings for business expansion[810](index=810&type=chunk) [Additional Information](index=170&type=section&id=ITEM%2010.%20ADDITIONAL%20INFORMATION) This section provides supplementary corporate details, including material tax considerations for investors [Taxation](index=170&type=section&id=E.%20Taxation) This subsection details material tax considerations in Singapore, Malaysia, and the U.S., including PFIC risks - Singapore Tax: Dividends paid by the company are **tax-exempt** to shareholders under the one-tier system and Singapore does not impose tax on capital gains[831](index=831&type=chunk)[833](index=833&type=chunk)[834](index=834&type=chunk) - Malaysia Tax: Malaysia operates on a territorial tax principle and **dividends distributed by Malaysian companies are exempt** from tax in the hands of shareholders[847](index=847&type=chunk)[858](index=858&type=chunk) - U.S. Federal Income Tax: The company does not expect to be a Passive Foreign Investment Company (PFIC), but its status is an annual determination and **PFIC classification would result in adverse tax treatment** for U.S. Holders[870](index=870&type=chunk) [PART II](index=180&type=section&id=PART%20II) [Material Modifications to the Rights of Security Holders and Use of Proceeds](index=180&type=section&id=ITEM%2014.%20MATERIAL%20MODIFICATIONS%20TO%20THE%20RIGHTS%20OF%20SECURITY%20HOLDERS%20AND%20USE%20OF%20PROCEEDS) This section confirms no changes to shareholder rights and updates the use of IPO proceeds [Use of Proceeds](index=180&type=section&id=E.%20Use%20of%20Proceeds) The company raised S$10.31 million in net IPO proceeds in April 2023 with no material change in their planned use - The company raised approximately **S$10.31 million in net proceeds** from its IPO, which was completed on April 18, 2023[891](index=891&type=chunk) - As of December 31, 2024, the company confirms **no material change in the use of proceeds** from its registration statement[892](index=892&type=chunk) [Controls and Procedures](index=180&type=section&id=ITEM%2015.%20CONTROLS%20AND%20PROCEDURES) Management concluded that disclosure controls and procedures were effective as of December 31, 2024 - Management concluded that the company's **disclosure controls and procedures were effective** as of December 31, 2024[893](index=893&type=chunk) - As a newly public company, the annual report does not yet include a management assessment or auditor attestation on internal control over financial reporting, per SEC transition rules[896](index=896&type=chunk)[897](index=897&type=chunk) [Corporate Governance and Other Disclosures](index=182&type=section&id=ITEM%2016.%20CORPORATE%20GOVERNANCE%20AND%20OTHER%20DISCLOSURES) This section details corporate governance matters, including committee experts, accountant fees, and cybersecurity risks - The board has determined that **Mark LEONG Kei Wei is an "Audit Committee Financial Expert"**[900](index=900&type=chunk) Principal Accountant Fees (WWC, P.C.) | Fee Type | 2022 (U.S.$) | 2023 (U.S.$) | 2024 (U.S.$) | | :--- | :--- | :--- | :--- | | Audit Fees | 70,000 | 85,000 | 95,000 | | Audit-Related Fees | 18,000 | 20,000 | 20,000 | - As a **foreign private issuer**, the company follows Singaporean corporate governance practices, opting out of certain Nasdaq rules[909](index=909&type=chunk) - The company has implemented protocols to manage cybersecurity risks, overseen by the Chief Corporate Officer, Ms. TAN Yoong Ying, who reports to the board[919](index=919&type=chunk)[921](index=921&type=chunk) [PART III](index=185&type=section&id=PART%20III) [Financial Statements](index=185&type=section&id=ITEM%2018.%20FINANCIAL%20STATEMENTS) This section contains the company's audited consolidated financial statements for fiscal years 2022, 2023, and 2024 Consolidated Statement of Financial Position (S$) | As of December 31 | 2023 | 2024 | | :--- | :--- | :--- | | **Total Assets** | 12,368,870 | 10,067,749 | | **Total Liabilities** | 1,124,715 | 1,023,960 | | **Total Equity** | 11,244,155 | 9,043,789 | Consolidated Statement of Profit or Loss (S$) | For the Year Ended December 31 | 2022 | 2023 | 2024 | | :--- | :--- | :--- | :--- | | **Revenue** | - | - | 69,501 | | **Loss for the year** | (3,131,452) | (4,133,170) | (2,521,861) | | **Total comprehensive loss for the year** | (3,227,956) | (4,223,088) | (2,358,216) |