Blood Version 1 Version 2 CRC Sensitivity 84% 91% Study Results • Samples were run on both V1 and V2 tests ) GUARDANT Source: Guardant internal data Adding Shield to standard of care increases compliance meaningfully Randomized prospective study with Kaiser Permanente Center for Health Research ACG ** 2023 9 Shield V2 demonstrated improved clinical sensitivity relative to Shield V1 CRC Sensitivity N = 45 Specificity N = 1,458 84% (38/45) 91% Shield V1 – PMA device Shield V2 91% (41/45) 91% CRC Sensitivity N ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 _____________________ FORM 10-Q _____________________ (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-38683 _____________________ GUARDANT HEALTH, INC. (Exact Name of Registrant as Sp ...

Guardant Health, Inc. (NASDAQ:GH) Q2 2023 Earnings Conference Call August 3, 2023 4:30 PM ET Company Participants Carrie Mendivil - IR Helmy Eltoukhy - Co-Founder, Co-CEO & Chairman AmirAli Talasaz - Co-CEO & Director Michael Bell - CFO Conference Call Participants Jack Meehan - Nephron Research Puneet Souda - Leerink Partners Patrick Donnelly - Citigroup David Delahunt - Goldman Sachs Group Daniel Leonard - Crédit Suisse Andrew Brackmann - William Blair & Company Sung Ji Nam - Scotiabank Operator Hello, ev ...

In light of the foregoing, investors are urged not to rely on any forward-looking statement or third-party data in reaching any conclusion or making any investment decision about any securities of the Company. High growth core business approaching breakeven with a potentially higher growth pipeline Growth in TissueNext, differentiated by our Lunit-powered Galaxy AI TECHNOLOGY LEADER Pipeline of multi-billion dollar revenue opportunities in early stages Spearheading a new patient-preferred category with Shie ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 _____________________ FORM 10-Q _____________________ OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 (Mark One) For the transition period from to ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-38683 _____________________ For the quarterly period ended June 30, 2023 GUARDANT HEALTH, INC. (Exact Name of Registrant as Specifi ...

Guardant Health, Inc. (NASDAQ:GH) Q1 2023 Earnings Conference Call May 9, 2023 4:30 PM ET Company Participants Alex Kleban - Vice President-Investor Relations Helmy Eltoukhy - Chairman & Co-Chief Executive Officer AmirAli Talasaz - Co-Chief Executive Officer Mike Bell - Chief Financial Officer Craig Eagle - Chief Medical Officer Conference Call Participants Dan Arias - Stifel Puneet Souda - SVB Securities Jack Meehan - Nephron Research Kyle Mikson - Canaccord Julia Qin - JPMorgan Dave Delahunt - Golden Sach ...

Safe harbor achievements to differ materially from those expressed or implied by these forward-looking statements. The forward-looking statements in this presentation are made only as of the date hereof. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward- looking statements, as well as risks relating to the business of the Company in general, see the Company's periodic filings with the Securities and Exchange Commission, i ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 _____________________ FORM 10-Q _____________________ (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-38683 _____________________ GUARDANT HEALTH, INC. (Exact Name of Registrant as Specif ...

Shield LDT screening commercial team • Implementing efficiencies and workforce reduction across all areas of the business • Therapy Selection on-track to be breakeven in ~12 months • $1B cash balance provides >3 year runway and will fund continued investments in MRD and Screening 16 FY 2023 guidance ▪ Total Revenue: $525 – $540 million, growth of 17% to 20% y/y ▪ Precision Oncology Revenue: >20% growth over 2022 ▪ Development Services & Other Revenue: > $50 million ▪ Operating Expenses: below FY 2022 ▪ Free ...

Guardant Health, Inc. (NASDAQ:GH) Q4 2022 Earnings Conference Call February 23, 2023 4:30 PM ET Company Participants Alex Kleban – Vice President-Investor Relations Helmy Eltoukhy – Chairman and Co-Chief Executive Officer AmirAli Talasaz – Co-Chief Executive Officer Mike Bell – Chief Financial Officer Conference Call Participants Dan Arias – Stifel Max Masucci – Cowen Tejas Savant – Morgan Stanley Derik De Bruin – Bank of America Jack Meehan – Nephron Julia Qin – JPMorgan Puneet Souda – SVB Securities Matt ...