ASC30 oral tablet demonstrated dose-proportional pharmacokinetic (PK) properties and a long half-life (t1/2) up to 60 hours in the single ascending dose (SAD) study of patients with obesity, supporting once-daily or less frequent oral dosing. ASC30 oral tablet was generally safe and well tolerated. All adverse events (AEs) were mild (grade 1) or moderate (grade 2), and most of the AEs were gastrointestinal (GI)-related. There were no grade 3 or higher AEs as well as no serious AEs (SAEs). Alanine aminotran ...

About this content About Emily Jarvie Emily began her career as a political journalist for Australian Community Media in Hobart, Tasmania. After she relocated to Toronto, Canada, she reported on business, legal, and scientific developments in the emerging psychedelics sector before joining Proactive in 2022. She brings a strong journalism background with her work featured in newspapers, magazines, and digital publications across Australia, Europe, and North America, including The Examiner, The Advocate, ...

In an unexpected move, Viking Therapeutics, Inc (NASDAQ: VKTX ) has been sold off hard since Donald Trump won the U.S. elections. A lot of the excitement in GLP-1s has disappeared in the last few months, despite noMark leads the investing group Out Fox The Street where he shares stock picks and deep research to help readers uncover potential multibaggers while managing portfolio risk via diversification. Features include various model portfolios, stock picks with identifiable catalysts, daily updates, real- ...

Novo Nordisk A/S TodayNVONovo Nordisk A/S$108.47 +0.46 (+0.43%) 52-Week Range$99.42▼$148.15Dividend Yield0.66%P/E Ratio35.10Price Target$150.40Add to WatchlistRecent sales of a little-known stock, Madrigal Pharmaceuticals NASDAQ: MDGL, could bode well for Novo Nordisk A/S NYSE: NVO. The pharma industry giant has seen explosive sales growth for its GLP-1 agonist drug, semaglutide. Marketed through the names Ozempic and Wegovy, sales of the drugs grew 32% and 76% through the first nine months of 2024, compar ...

CHICAGO, Dec. 12, 2024 /PRNewswire/ -- With the rising popularity of GLP-1 medications among Americans for diabetes and weight management, Conagra Brands is proud to announce a first-of-its-kind initiative in the food industry. Starting in January 2025, the company's Healthy Choice® line will feature an "On Track" badge on 26 select items, indicating that the products are high in protein, low calorie, and a good source of fiber, which make these items "GLP-1 friendly." Healthy Choice is the first major food ...

There's a growing number of companies entering the weight loss space, focusing on GLP-1 drugs which can be game changers for their businesses. And one of them is Viking Therapeutics (VKTX -2.70%), which has a promising GLP-1 treatment in development that investors are hopeful will generate billions in revenue for the modestly sized healthcare company. It may even lead to an acquisition.In the past month, however, excitement around Viking has cooled, considerably. During November, the stock fell by 27%, hitt ...

Though the stock market has raced to fresh all-time highs over the past month, the mood is anything but complacent as we head toward a potentially fractious election amid an uncertain macroeconomy. And one of the most volatileWith combined experience of covering technology companies on Wall Street and working in Silicon Valley, and serving as an outside adviser to several seed-round startups, Gary Alexander has exposure to many of the themes shaping the industry today. He has been a regular contributor on S ...

Preclinical data from ex vivo human islet experiments showed that icovamenib (BMF-219) was able to enhance the activity of glucagon-like peptide-1 (GLP-1)-based therapies, potentially leading to increased insulin secretion and improved glycemic control in patients with diabetes Phase II study (COVALENT-211), combining icovamenib with a GLP-1-based therapy, planned to begin in 2025 BMF-650, an investigational next-generation, oral small-molecule GLP-1 receptor agonist (GLP-1 RA), demonstrated positive early ...

Core Insights - The article discusses the potential of Viking Therapeutics as a competitor in the GLP-1 market, currently dominated by Novo Nordisk, particularly focusing on its drug candidate VK2735, a dual GLP-1 and GIP receptor agonist aimed at treating obesity [1][2]. Company Overview - Viking Therapeutics is developing VK2735, which may offer a more effective treatment for obesity and diabetes compared to existing single-pathway GLP-1 medications like Ozempic and Wegovy [2]. - The company plans to meet with the FDA in Q4 to discuss the next steps for VK2735, including moving into phase 3 clinical trials [2]. Financial Position - Viking's stock has surged by 323% in 2024, leading to a market capitalization of approximately $8.8 billion, despite the company not generating revenue [4]. - As of the end of Q3, Viking had $930 million in cash and equivalents, with an annual run rate of about $140 million in operating expenses, indicating strong liquidity for ongoing operations [4]. Investment Considerations - The stock is viewed as a speculative opportunity, with encouraging clinical trial data but significant uncertainties surrounding the phase 3 study [5]. - The current stock price may reflect an overbought condition, suggesting that potential upside from VK2735's approval may already be factored into the share price [5]. - While Viking could become a disruptive player in the weight loss market, its full potential may take years to realize, and Novo Nordisk is expected to maintain its leadership in diabetes treatment and weight management in the meantime [5][6].

Core Insights - The article promotes a marketplace channel, Haggerston BioHealth, which offers exclusive stock tips focused on the Pharma, Biotech, and Healthcare sectors [1] - The group caters to both novice and experienced biotech investors, providing insights on catalysts, buy and sell ratings, and detailed financial analyses [1] Group 1 - The channel provides product sales forecasts and integrated financial statements for major pharmaceutical companies [1] - It includes discounted cash flow analysis and market-by-market analysis to aid investment decisions [1] - The lead consultant, Edmund Ingham, has extensive experience in the biotech and healthcare sectors, having covered over 1,000 companies [1]