Exhibit 99.1 Iovance Biotherapeutics Reports Financial Results and Corporate Updates for First Quarter 2025 1Q25 Total Product Revenue of $49.3M FY25 Total Product Revenue Guidance Revised to $250M-$300M FY25 Operating Expenses Reduced and 2H26 Cash Runway Guidance Maintained 2025 Regulatory Approvals for Amtagvi® Expected in the UK, EU, and Canada On Track to Report Updated Clinical Data for Registrational Trial in Previously Treated Advanced NSCLC in 2H25 SAN CARLOS, Calif., May 8, 2025 -- Iovance Biother ...

1Q25 Total Product Revenue of $49.3M FY25 Total Product Revenue Guidance Revised to $250M-$300M FY25 Operating Expenses Reduced and 2H26 Cash Runway Guidance Maintained 2025 Regulatory Approvals for Amtagvi® Expected in the UK, EU, and Canada On Track to Report Updated Clinical Data for Registrational Trialin Previously Treated Advanced NSCLC in 2H25 SAN CARLOS, Calif., May 08, 2025 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a commercial biotechnology company focused on innovating, ...

SAN CARLOS, Calif., May 02, 2025 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a biotechnology company focused on innovating, developing, and delivering novel polyclonal tumor infiltrating lymphocyte (TIL) therapies for patients with cancer, will report its first quarter 2025 financial results and corporate updates on Thursday, May 8, 2025. Management will host a conference call and live audio webcast to discuss these results and provide a corporate update on May 8, 2025 at 4:30 p.m. ET. ...

SAN CARLOS, Calif., April 23, 2025 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a biotechnology company focused on innovating, developing, and delivering novel polyclonal tumor infiltrating lymphocyte (TIL) therapies for patients with cancer, announced that pre-clinical data for IOV-5001, a genetically engineered, inducible, and tethered interleukin-12 (IL-12) TIL cell therapy, will be presented at the 2025 AACR Annual Meeting. In addition, five-year outcomes data from the C-144-01 stud ...

Core Viewpoint - Iovance Biotherapeutics has an approved drug, Amtagvi, for treating unresectable or metastatic melanoma, but its stock has significantly declined, raising concerns among investors about its future performance [1][2]. Group 1: Stock Performance and Market Sentiment - Iovance's stock has fallen approximately 57% since the beginning of the year as of April 22, indicating a significant sell-off [5]. - The percentage of short-sellers in relation to Iovance's float has been increasing, reflecting growing skepticism about the company's future success [3]. Group 2: Financial Health and Cash Flow - Iovance is experiencing poor cash flow, which may lead to further dilution for shareholders as the company has historically relied on issuing stock to fund operations [11]. - As of the end of 2024, Iovance had cash and short-term investments totaling $323.8 million, but ongoing high cash burn could deplete this cushion over time [10]. Group 3: Future Revenue Potential - Although Amtagvi has the potential to generate $1 billion in annual revenue, this is not expected until 2030, which raises concerns about the company's ability to achieve profitability in the near term [7][12]. - Iovance reported a net loss of $372.2 million last year, highlighting the financial challenges it faces [12].

Some investors see a striking similarity between lottery tickets and biotech stocks. In most cases, buying lottery tickets ends up being a waste of money. So does investing in most biotech stocks. But just as one lucky lottery ticket can provide game-changing wealth, so can the right biotech stock.Iovance Biotherapeutics (IOVA 0.30%) just might be the right kind of biotech stock. The company has already achieved success. Could it even be a millionaire-maker?Iovance's opportunityTo appreciate Iovance's oppor ...

Core Viewpoint - Iovance Biotherapeutics has innovative cancer therapies but faces challenges in market performance despite regulatory approval of its key therapy, Amtagvi [1][2]. Company Overview - Iovance Biotherapeutics specializes in developing therapies using tumor-infiltrating lymphocytes (TILs) to target cancer cells [3]. - The company’s flagship product, Amtagvi, is a personalized treatment for melanoma that received FDA approval last year [3][4]. Market Performance - The stock has declined by 74% over the past 12 months, trading under $4 per share, which is close to its 52-week low [2]. - Analysts have a bullish outlook, with price targets ranging from $6 to $32, and an average target of $19.54 [2]. Product Details - Amtagvi takes 34 days to manufacture and is administered in specialized treatment centers, which complicates its rollout [4]. - Iovance reported $164.1 million in revenue last year and has only begun to address the 20,000 eligible melanoma patients in the U.S. [5]. Market Potential - There are an estimated 325,000 annual melanoma cases worldwide, indicating a significant market opportunity for Iovance [6]. - The company is seeking regulatory approvals in additional countries, potentially expanding its patient base by 2025 [5][8]. Future Projections - Iovance anticipates product revenue for Amtagvi to be between $450 million and $475 million in 2025 [9]. - The company has a pipeline of over a dozen programs, including trials for non-small cell lung cancer, which could serve as catalysts for growth [10]. Financial Outlook - Iovance aims to keep its cash burn under $300 million for 2025, which is below its projected revenue range [11]. - The company improved its net loss per share from $1.89 in 2023 to $1.28 in 2024, indicating progress in financial performance [12].

The time to buy quality prospects is when the rest of the market is ignoring their value.Most investors know the market's down quite a bit from February's high. Not all investors realize that a handful of compelling stocks were already sliding before the marketwide correction started, and that several of these same names haven't yet even hinted at a recovery. Wall Street's seemingly given up on them, looking right past everything that makes these companies -- and their stocks -- so promising.Not me, though. ...

When a stock is in a freefall, there's usually a justifiable reason for the decline. But for investors with a high risk tolerance, it could make for a potentially attractive contrarian play. A stock that has fallen to a fraction of its price could possess significant upside if it's able to prove its doubters wrong.One stock that's down big of late is Iovance Biotherapeutics (IOVA -1.28%). Entering trading this week, the healthcare stock has lost close to 60% of its value in the past three months, and it's d ...

After working as a Registered Nurse for several years, I transitioned into financial analysis, earning my MBA and developing expertise in healthcare & technology investments. Since 2017, I've published investment analyses on Seeking Alpha, focusing on thorough valuation modeling. My approach centers on examining core assumptions that drive stock valuations, particularly through detailed discounted cash flow analysis. I provide readers with various scenarios to help them understand potential outcomes. The pr ...