Exhibit 99.1 Pyxis Tankers Announces Financial Results for the Three Months and Year Ended December 31, 2021 Maroussi, Greece, March 18, 2022 – Pyxis Tankers Inc. (NASDAQ Cap Mkts: PXS), (the "Company" or "Pyxis Tankers"), a growth- oriented pure play product tanker company, today announced unaudited results for the three months and year ended December 31, 2021. Summary For the three months ended December 31, 2021, our Revenues, net were $8.1 million. For the same period, our time charter equivalent ("TCE") ...

Financial Data and Key Metrics Changes - For Q4 2021, the company generated time charter equivalent revenues of $3.9 million, a 9% increase from the same period in 2020, primarily due to the addition of one MR vessel [7] - The company reported a net loss of $5.6 million in Q4 2021, significantly higher than the loss of $2.7 million in the same period last year, attributed to higher costs and a $2.4 million noncash loss on the sale of two small tankers [8][28] - Adjusted EBITDA for Q4 2021 was a negative $700,000, reflecting challenging chartering conditions [8][29] Business Line Data and Key Metrics Changes - The average daily time charter equivalent for MRs was approximately $8,700, dramatically lower than the previous year's figure [9] - Fleet-wide daily TCE was approximately $8,000 in Q4 2021, significantly lower than the comparable 2020 period [27] Market Data and Key Metrics Changes - Global inventories of refined petroleum products are below 5-year averages, with prices at or near record levels, indicating a volatile and unpredictable demand for product tankers [12] - The outlook for 2022 global growth is likely to be revised downward due to geopolitical tensions and inflation, which may soften charter activity [17] Company Strategy and Development Direction - The company has developed a better strategic, operational, and financial platform over the last two years, raising over $36 million in equity capital and $75 million in lower-cost long-lived bank debt [13] - The company continues to use a mixed chartering strategy of short time and spot charters to position itself for better chartering markets ahead [14] Management's Comments on Operating Environment and Future Outlook - Management expressed concerns about potential slowdowns in Europe and China, while remaining positive about improving economic activities in the United States [11] - The company is optimistic about the long-term supply-demand fundamentals for the product tanker sector, with expectations of interesting opportunities in the spot market [32] Other Important Information - The MR2 order book is drifting lower, with only 2 new orders in the first two months of 2022, indicating a subdued new ordering environment [22] - The company expects annual net fleet growth for MRs to be around 2% this year and next, supported by ongoing demolitions of older vessels [25] Q&A Session Summary Question: What are the expectations for the product tanker market in the near future? - Management indicated that while there are interesting opportunities in the spot market, the demand for product tankers has become volatile and unpredictable due to geopolitical events and economic conditions [12][32] Question: How is the company managing its fleet and chartering strategy? - The company continues to focus on a mixed chartering strategy and diversification by charter counterparty and duration to better position itself for future market improvements [14] Question: What is the outlook for new vessel orders and fleet growth? - The company noted that new vessel ordering has been subdued, with expectations of a 2% annual net fleet growth for MRs, driven by low new vessel ordering and high scrapping rates [22][25]

PYXIS COMPANY PRESENTATION January 2022 DISCLAIMER & FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements and forward-looking information within the meaning of the Private Securities Litigation Reform Act of 1995 applicable securities laws. The words "expected'', "estimated", "scheduled", "could", "should", "anticipated", "long-term", "opportunities", "potential", "continue", "likely", "may", "will", "positioned", "possible", "believe", "expand" and variations of these terms and ...

PYXIS COMPANY PRESENTATION November 2021 DISCLAIMER & FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements and forward-looking information within the meaning of the Private Securities Litigation Reform Act of 1995 applicable securities laws. The words "expected'', "estimated", "scheduled", "could", "should", "anticipated", "long-term", "opportunities", "potential", "continue", "likely", "may", "will", "positioned", "possible", "believe", "expand" and variations of these terms and ...

Pyxis Tankers Inc. (NASDAQ:PXS) Q3 2021 Results Earnings Conference Call November 15, 2021 4:30 PM ET Company Participants Valentios Valentis - Chairman and Chief Executive Officer Henry Williams - Chief Financial Officer and Treasurer Conference Call Participants Operator Good day and welcome to the Pyxis Tankers Conference Call to discuss the Financial Results for the Third Quarter 2021. As a reminder, today's call is being recorded. Additionally, a live webcast of today's conference call and an accompany ...

Exhibit 99.1 September 30, 2021 TO THE SHAREHOLDERS OF PYXIS TANKERS INC. Enclosed is a Notice of the 2021 Annual Meeting of Shareholders (the "Meeting") of Pyxis Tankers Inc. (the "Company"), which will be held at the Company's offices at 59, K. Karamanli Street, Maroussi 15125, Greece on Thursday, November 11, 2021 at 4:30 p.m., Greek time, the Company's Proxy Statement and certain other related materials. These materials, together with the Company's annual report on Form 20-F, which contains the Company' ...

Pyxis Tankers Inc. (NASDAQ:PXS) Q2 2021 Earnings Conference Call August 9, 2021 8:30 AM ET Company Participants Eddie Valentis - Chairman and CEO Henry Williams - CFO Conference Call Participants Operator Good day and welcome to the Pyxis TankersÂ' Conference Call to discuss the Financial Results for the Second Quarter 2021. As a reminder, today's call is being recorded. Additionally, a live webcast of today's conference call and an accompanying presentation is available on Pyxis TankersÂ' website, which is ...

PYXIS TANKERS Q2 2021 Financial Results August 9, 2021 DISCLAIMER FORWARD-LOOKING STATEMENTS & INFORMATION This presentation contains forward-looking statements and forward-looking information within the meaning of the Private Securities Litigation Reform Act of 1995 applicable securities laws. The words "expected'', "estimated", "scheduled", "could", "should", "anticipated", "long-term", "opportunities", "potential", "continue", "likely", "may", "will", "positioned", "possible", "believe", "expand" and var ...

PYXIS Q1 2021 Financial Results June 2, 2021 DISCLAIMER FORWARD-LOOKING STATEMENTS & INFORMATION This presentation contains forward-looking statements and forward-looking information within the meaning of the Private Securities Litigation Reform Act of 1995 applicable securities laws. The words "expected'', "estimated", "scheduled", "could", "should", "anticipated", "long-term", "opportunities", "potential", "continue", "likely", "may", "will", "positioned", "possible", "believe", "expand" and variations of ...

Pyxis Tankers Inc. (NASDAQ:PXS) Q1 2021 Earnings Conference Call June 2, 2021 8:30 AM ET Company Participants Eddie Valentis - Chairman & Chief Executive Officer Henry Williams - Chief Financial Officer Conference Call Participants Operator Good day and welcome to the Pyxis TankersÂ' Conference Call to discuss the Financial Results for the First Quarter 2021. As a reminder, today's call is being recorded. Additionally, a live webcast of today's conference call and an accompanying presentation is available o ...