Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36294 uniQure N.V. (Exact name of Registrant as specified in its charter) The Netherlands (Jurisdiction of incorpor ...

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| --- | --- | --- | --- | --- | |-------------------------------------------|-------|-------|-------|-------| | | | | | | | | | | | | | | | | | | | | | | | | | Global License Agreement in Hemophilia B | | | | | | June 24, 2020 | | | | | | | | | | | | | | | | | Forward-looking Statements A G L O B A L L E A D E R I N G E N E T H E R A P Y J A N U A R Y 2 0 2 0 | 2 This presentation contains forward-looking statements. All statements other than statements of historical fact are forward-looking statements, whi ...

| --- | --- | --- | --- | --- | --- | |------------------------|-------|-------|-------|-------|-------| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | A Global Leader in | | | | | | | Gene Therapy | | | | | | | Corporate Presentation | | | | | | | April 2020 | | | | | | uniQure A G L O B A L L E A D E R I N G E N E T H E R A P Y A P R I L 2 0 2 0 | 2 Forward-looking Statements This presentation contains forward-looking statements. All statements other than statements ...

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uniQure Delivering Gene Therapy to Patients Corporate Presentation November 2019 D E L I V E R I N G G E N E T H E R A P Y T O P A T I E N T S N O V E M B E R 2 0 1 9 | 2 Forward-looking Statements This presentation contains forward-looking statements. All statements other than statements of historical fact are forward-looking statements, which are often indicated by terms such as "anticipate," "believe," "could," "estimate," "expect," "goal," "intend," "look forward to," "may," "plan," "potential," "predic ...

uniQure Delivering Gene Therapy to Patients Cantor Global Healthcare Conference October 2, 2019 D E L I V E R I N G G E N E T H E R A P Y T O P A T I E N T S S E P T E M B E R 2 0 1 9 | 2 Forward-looking Statements This presentation contains forward-looking statements. All statements other than statements of historical fact are forward-looking statements, which are often indicated by terms such as "anticipate," "believe," "could," "estimate," "expect," "goal," "intend," "look forward to," "may," "plan," "po ...

uniQure Delivering Gene Therapy to Patients Corporate Presentation AULY 2019 DELIVERING GENE THERAPY TO PATIENTS JULY 2019 | 2 Forward-looking Statements This presentation contains forward-looking statements. All statements other than statements of historical fact are forward-looking statements, which are often indicated by terms such as "anticipate," "believe," "could," "estimate," "expect," "goal," "intend," "look forward to," "may," "plan," "potential," "predict," "project," "should," "will," "would" and ...