PresentationWelcome to 22nd Century Group's Fourth Quarter and Full Year 2025 Conference Call and Webcast. [Operator Instructions] It is now my pleasure to turn the floor over to Matt Kreps, Investor Relations for 22nd Century Group. Please go ahead.Matthew KrepsInvestor Relations Thank you. Hello, and welcome to 22nd Century's Fourth Quarter and Full Year 2025 Results Conference Call. Joining me today are Larry Firestone, CEO; and Dan Otto, CFO. Earlier today, we issued a press release announcing our resul ...

22nd Century Group (NasdaqCM:XXII) Q4 2025 Earnings call March 26, 2026 08:00 AM ET Company ParticipantsDan Otto - CFOLarry Firestone - CEOMatt Kreps - Director of Investor RelationsOperatorWelcome to 22nd Century Group's fourth quarter and full year 2025 conference call and webcast. At this time, all participants have been placed in a listen-only mode. It is now my pleasure to turn the floor over to Matt Kreps, investor relations for 22nd Century Group. Please go ahead.Matt KrepsThank you. Hello, and welco ...

22nd Century Group (NasdaqCM:XXII) Q4 2025 Earnings call March 26, 2026 08:00 AM ET Company ParticipantsDan Otto - CFOLarry Firestone - CEOMatt Kreps - VP of Investor RelationsOperatorWelcome to 22nd Century Group's fourth quarter and full year 2025 conference call and webcast. At this time, all participants have been placed in a listen-only mode. It is now my pleasure to turn the floor over to Matt Kreps, investor relations for 22nd Century Group. Please go ahead.Matt KrepsThank you. Hello, and welcome to ...

22nd Century Group (NasdaqCM:XXII) Q4 2025 Earnings call March 26, 2026 08:00 AM ET Speaker3Welcome to 22nd Century Group's fourth quarter and full year 2025 conference call and webcast. At this time, all participants have been placed in a listen-only mode. It is now my pleasure to turn the floor over to Matt Kreps, investor relations for 22nd Century Group. Please go ahead.Speaker2Thank you. Hello, and welcome to 22nd Century's fourth quarter and full year 2025 results conference call. Joining me today are ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ Annual Report under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2025 or ☐ Transition Report under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number: 001-36338 22nd Century Group, Inc. (Exact name of registrant as specified in its charter) (State or other jurisdiction (IRS Employer Nevada 98-0468420 of incorporation) Identification No.) 321 ...

VLN® Commercial Expansion Drives Continued Shift Toward Higher Margin Proprietary Branded Products Expanding VLN® Store Counts and State Authorizations Increase Availability of Smoking Harm Reduction Products MOCKSVILLE, N.C., March 26, 2026 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), the only tobacco products company focused on reducing the harms of smoking through nicotine reduction, today announced results for the fourth quarter and fiscal year-ended December 31, 2025, and provided an up ...

MOCKSVILLE, N.C., March 23, 2026 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), the only tobacco products company that has for 27 years led and continues to lead the fight against the harms of smoking driven by nicotine addiction, will host a webcast on Thursday, March 26, 2026, at 8:00 AM ET to discuss its 2025 fourth quarter and full year results, which are to be reported in a press release at 6:00 AM ET the same day. During the webcast, Larry Firestone, chairman and chief executive officer, ...

Core Insights - 22nd Century Group, Inc. is experiencing early sales momentum for its VLN low nicotine cigarette products in the U.S. market, with plans to expand to over 5,000 retail outlets by 2026 as consumer interest grows [1][5][8] Group 1: Product and Technology - The company's proprietary low nicotine technology aims to help adult smokers reduce nicotine consumption, providing an alternative to highly addictive products like vapes [2] - VLN low nicotine combustible cigarettes are the only FDA-authorized cigarettes designed to help reduce nicotine consumption, with a nicotine content of 95% less than traditional cigarettes [10][13] - The technology is based on non-GMO reduced nicotine tobacco plants developed through patented methods, ensuring commercial scalability [12] Group 2: Regulatory Environment - The U.S. FDA proposed a rule in January 2025 to mandate a maximum nicotine level of 0.7 milligrams per gram in combustible cigarettes, positioning VLN favorably in this evolving regulatory landscape [3] - The WHO Framework Convention on Tobacco Control supports nicotine reduction as a strategy for reducing tobacco dependence, aligning with the company's mission [4] Group 3: Market Opportunity and Sales Traction - In Q4 2025, approximately 8,800 cartons of VLN cigarettes were distributed across about 1,700 new retail outlets, indicating strong early consumer adoption [5] - The company is expanding its distribution strategy by securing placements with large convenience store retailers and wholesalers to increase visibility and access [7] - Early adoption of VLN products validates the company's belief that there is a significant underserved market of adult smokers seeking alternatives [6][8] Group 4: Future Outlook - The company anticipates sustained smoker adoption of VLN products and plans to grow its retail footprint significantly in the coming years [8] - There is growing international interest in the company's proprietary low nicotine tobacco leaf, indicating potential for global expansion [8][9]

FORM 8-K CURRENT REPORT UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 20, 2026 22nd Century Group, Inc. (Exact Name of Registrant as Specified in Charter) Nevada 001-36338 98-0468420 (State or Other Jurisdiction of Incorporation) (Commission File Number) (I.R.S. Employer Identification No.) 321 Farmington Rd., Mocksville, North Carolina 27028 (Address of ...

Core Insights - 22nd Century Group, Inc. ended 2025 with $7.1 million in cash and is debt-free, which supports its transition to growth [1][5] - The company is focusing on the commercial expansion of its VLN brand, which is expected to drive a shift towards higher-margin proprietary branded products [1][3] Preliminary Financial Results - The company anticipates fourth quarter 2025 net revenues of approximately $3.6 million, down from $4.0 million in the third quarter of 2025 [5] - For the full year 2025, net revenues are expected to be around $17.6 million, a decrease from $24.4 million in 2024 [5] - Total cartons shipped in the fourth quarter 2025 were approximately 0.3 million, compared to 0.5 million in the third quarter of 2025 [5] - The expected gross loss for the fourth quarter 2025 is approximately $0.8 million, an improvement from $1.1 million in the third quarter [5] - The expected operating loss for 2025 is $11.6 million, down from $14.0 million in 2024 [5] - Cash and equivalents at year-end were $7.1 million, with zero long-term debt after extinguishing remaining senior secured debt in 2025 [5] Strategic Focus - The company aims to expand VLN product distribution and consumer awareness while maintaining disciplined cost management and capital allocation [3] - The groundwork for growth is being laid following the fourth quarter launch of VLN and Partner VLN brands [3] - The company remains engaged with the FDA and public health stakeholders to drive health and wellness initiatives for smokers [3]