Exhibit 99.1 22nd Century Group (XXII) Reports Fourth Quarter 2023 Financial Results MOCKSVILLE, N.C., March 28, 2024 — 22nd Century Group, Inc. (Nasdaq: XXII), a tobacco products company focused on nicotine harm reduction, today reported results for the fourth quarter ended December 31, 2023, and provided an update on recent business highlights. Fourth quarter results and recent business activities included: Said Larry Firestone, Chairman and CEO: "Our turnaround is progressing rapidly, after restructuring ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended September 30, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period From ________ to ________ Commission File Number: 001-36338 22nd Century Group, Inc. (State or other jurisdiction (IRS Employer of incorporation) Identific ...

22nd Century Group, Inc. (NASDAQ:XXII) Q2 2023 Earnings Conference Call August 14, 2023 8:00 AM ET Company Participants Matt Kreps - IR Hugh Kinsman - CFO John Miller - Interim CEO Conference Call Participants Vivien Azer - TD Cowen Jim McIlree - Dawson James Operator Good morning, ladies and gentlemen, and welcome to the 22nd Century Group Second Quarter 2023 Results Conference Call. [Operator Instructions] I would now like to turn the conference over to Mr. Matt Kreps. Please go ahead, sir. Matt Kreps Tha ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended June 30, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period From ________ to ________ Commission File Number: 001-36338 22nd Century Group, Inc. (Exact name of registrant as specified in its charter) (State or other juri ...

Financial Data and Key Metrics Changes - Net sales increased 144% quarter-over-quarter to $22 million, reflecting the addition of GVB revenue [48] - Gross profit is projected to improve significantly in Q2 2023 due to a higher margin product mix and the return of production capabilities [49] - Revenue guidance for fiscal year 2023 is set at $105 million to $110 million, representing a 69% to 77% increase from $62 million in 2022 [13][53] Business Line Data and Key Metrics Changes - Tobacco revenue for Q1 remained relatively unchanged at $8.9 million, with gross profit slightly decreasing to $18,000 due to a reallocation towards higher margin products [50] - Hemp/cannabis revenue grew 85% to $13 million from $7 million, driven by strong customer demand for bulk ingredient products [51] - The company reported record cannabinoid ingredient volumes, delivering over 68,000 kilograms in Q1, four times the amount delivered in the same quarter last year [39] Market Data and Key Metrics Changes - The VLN rollout is occurring at twice the speed of a typical tobacco product rollout, with plans to expand from 500 stores to 5,000 [16][20] - The company has secured major national-scale distribution agreements, enabling rapid placement of VLN into thousands of stores across multiple states [14][20] - The hemp/cannabis business is positioned as a market leader in North America, with a focus on expanding sales and distribution capabilities [37] Company Strategy and Development Direction - The company aims to achieve cash positive operations in 2024, focusing on growth in both tobacco and hemp/cannabis business units [7][15] - Strategic initiatives include cost-cutting measures and a focus on high-margin products, with a commitment to not solely rely on cost reductions for success [8][15] - The company is enhancing consumer marketing strategies to drive awareness and acceptance of VLN, positioning it as a solution for smokers [23][24] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving revenue targets and highlighted the importance of business interruption insurance in improving financial results [9][52] - The company anticipates significant margin expansion in the second half of 2023 due to restored production capacity and new distribution agreements [13][49] - Management emphasized the importance of federal regulations and potential market opportunities arising from reduced nicotine content mandates [34] Other Important Information - The company received $5 million in insurance proceeds from the Grass Valley fire in Q1, with additional proceeds of approximately $8 million expected in Q2 [52] - The company is actively pursuing international market opportunities, with tests planned in Switzerland and Japan [30][31] Q&A Session Summary Question: Impact of shelf resets on VLN revenue generation - Management confirmed that VLN is included in retailer merchandising plans and is positioned to meet the needs of smokers [55] Question: Revenue growth expectations from tobacco - Approximately 60% to 70% of the expected revenue increase is driven by VLN, with the remainder from Pinnacle growth [57] Question: Timing and ramping of contracts with Old Pal and Cookies - Shipments from these contracts are expected to start in Q3, with significant ramp-up anticipated in Q4 and continuing into 2024 [60] Question: Price positioning of Pinnacle amidst down trading in U.S. cigarettes - Pinnacle is positioned competitively, similar to Lucky Strike, to attract consumers [63] Question: Update on VLN launch in priority states - The company is on track with plans for Arizona, New Mexico, and Utah, focusing on retailer demand and schematic changes [65] Question: Menthol market mix and marketing strategy - The company is monitoring menthol market dynamics and positioning VLN as a solution for menthol smokers [69] Question: Gross margin expectations for 2023 and 2024 - Expected gross margins for hemp could reach 20% to 30% by 2024, while tobacco margins are projected to expand significantly as VLN sales ramp up [82]

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended March 31, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period From ________ to ________ Commission File Number: 001-36338 22nd Century Group, Inc. (Exact name of registrant as specified in its charter) (State or other jur ...

X 22ND CENTURY GROUP FOURTH QUARTER AND FULL YEAR EARNINGS PRESENTATION MARCH 9, 2023 Nasdaq XXII SURGEON GENERAL'S WARNING: Ciparette HELPS YOU SMOKE LESS VLN® is deliberately different from all other traditional cigarettes, because VLN® is the only cigarette authorized by the FDA that Helps You Smoke Less. CAUTIONARY NOTE ON FORWARD-LOOKING STATEMENTS | --- | |----------------------------------------------------------------------------------------------------| | | | This presentation contains forward-look ...

22nd Century Group, Inc. (NASDAQ:XXII) Q4 2022 Earnings Conference Call March 9, 2023 10:00 AM ET Corporate Participants Matt Kreps - Investor Relations Jim Mish - Chief Executive Officer John Miller - President, Tobacco Business Hugh Kinsman - Chief Financial Officer Conference Call Participants Aaron Grey - Alliance Global Partners Vivien Azer - TD Cowen Alex Fuhrman - Craig-Hallum Capital Group Brian Wright - ROTH MKM Jim McIlree - Dawson James Operator Good day, ladies and gentlemen, and welcome to the ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ Annual Report under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2022 or ☐ Transition Report under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number: 001-36338 22nd Century Group, Inc. 500 Seneca Street, Suite 507, Buffalo, New York 14204 (Address of principal executive offices) (716) 270-1523 (Registrant's telephone number ...

22nd Century Group, Inc. (NASDAQ:XXII) Q3 2022 Earnings Conference Call November 8, 2022 10:00 AM ET Company Participants Mei Kuo - Director of Communications and Investor Relations James Mish - Chief Executive Officer John Miller - President, Tobacco Business Hugh Kinsman - Chief Financial Officer Conference Call Participants Vivien Azer - Cowen & Company Aaron Grey - Alliance Global Partners Brian Wright - Roth Capital Partners Jim McIlree - Dawson James Alex Fuhrman - Craig Hallum Operator Welcome to the ...