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康方生物(09926.HK):全球双抗龙头 依沃西引领二代IO新时代
AKESOAKESO(HK:09926) Ge Long Hui·2025-07-08 14:42

Core Viewpoint - 康方生物 is positioned to lead the next generation of tumor immunotherapy with its innovative dual-antibody platform and strong pipeline of products [1][2][3] Group 1: Company Overview - 康方生物 focuses on developing innovative antibody drugs, utilizing its ACE platform and Tetrabody technology to support over 20 pipelines [1] - The company achieved a significant milestone with the approval of AK104, the world's first PD-1/CTLA-4 dual antibody, in 2022 [1] - 康方生物 has a robust cash position of 7.3 billion RMB in 2024, which supports the commercialization of its pipeline [1] Group 2: Product Pipeline and Market Potential - AK112 has outperformed K drug in head-to-head trials and is expected to become a cornerstone product in the global immuno-oncology market, with peak revenue projections of 17.1 billion RMB by 2035 [2] - AK104 is the only approved PD-1/CTLA-4 dual antibody, with ongoing clinical trials expanding its indications, including cervical and gastric cancers [3] - The company anticipates rapid revenue growth from AK104 and AK112, with projected revenues of 3.67 billion, 5.34 billion, and 7.24 billion RMB for 2025-2027 [4] Group 3: Financial Projections and Valuation - The valuation of 康方生物 is projected at 160 billion HKD based on the potential of AK104 and AK112, with domestic revenue estimated at 3x PS and overseas at 15x PE [4] - The FCFF model indicates a target price of 163.33 RMB, suggesting significant upside potential compared to the closing price on July 7, 2025 [4]