AKESO(HK:09926) Zhi Tong Cai Jing·2025-08-27 01:37Core Viewpoint - CICC maintains the profit forecast for Kangfang Biopharma (09926) for 2025 and 2026, reiterating an outperform rating and raising the target price by 87.5% to HKD 225.00, indicating a 33.1% upside potential [1] Group 1: Financial Performance - The company's 1H25 revenue reached CNY 1.412 billion, representing a year-on-year growth of 37.75%, aligning with CICC's expectations [1] - The sales revenue of core products in 1H25 was CNY 1.402 billion, with a year-on-year increase of 49.2%, and a gross margin of 79.25%. The sales and marketing expense ratio decreased by 7.1 percentage points year-on-year to 47.80% [2] Group 2: Product Development and Clinical Trials - The final analysis of the HARMONi-A trial demonstrated statistically significant overall survival (OS) benefits for AK112 in treating 2L EGFRm NSCLC, with an OS hazard ratio of 0.80 and a maturity of 52%. This result highlights AK112's potential to significantly improve patient survival in a market with unmet clinical needs [3] - AK112 has 13 ongoing registration/Phase III clinical trials globally, covering indications beyond lung cancer. In the lung cancer domain, it has 8 registration/Phase III studies, with 4 achieving clinical endpoints. Additional trials are underway for various cancers, including biliary cancer and triple-negative breast cancer [4]