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云顶新耀(01952.HK)与VISARA订立协议于大中华区及其他亚洲市场开发及商业化VIS-101

Core Viewpoint - Company has entered into an exclusive licensing agreement with Visara, Inc. for the development, production, and commercialization of VIS-101 in Greater China, Singapore, South Korea, and several Southeast Asian countries, which is expected to provide significant therapeutic benefits for patients with various eye conditions [1][2] Group 1: Licensing Agreement Details - The agreement includes an upfront payment of $7 million (approximately RMB 49.7 million) and reimbursement of costs up to RMB 24 million [1] - Potential development and sales milestone payments could reach up to $89 million (approximately RMB 632 million) [1] - The company will also pay potential royalties based on net sales [1] Group 2: Product Information - VIS-101 is a novel dual-function biologic targeting VEGF-A and ANG-2, showing stronger efficacy compared to first-generation treatments [2] - It is expected to provide more durable therapeutic effects for patients with wet age-related macular degeneration, diabetic macular edema, and retinal vein occlusion [2] - VIS-101 has completed initial safety and dose-escalation studies in the US and China, and is currently undergoing a randomized dose-ranging Phase II clinical trial in China, with expectations to enter Phase III trials by 2026 [2]