来凯医药-B再涨超9% 乳腺癌候选新药LAE002斩获20.45亿元BD大单

Core Viewpoint - The stock of Lai Kai Pharmaceutical-B (02105) has seen a significant increase, rising over 9% and currently trading at 14.32 HKD, with a transaction volume of 92.6587 million HKD, following the announcement of a strategic partnership for its breast cancer candidate drug LAE002 [1] Group 1: Company Developments - On November 12, Lai Kai Pharmaceutical granted the rights for LAE002 in China to Qilu Pharmaceutical, with a total transaction value of 2.045 billion RMB [1] - The company is entitled to receive a tiered sales commission ranging from over 10% to over 20% [1] Group 2: Product Information - LAE002 is one of the two AKT inhibitors in late-stage clinical development targeting breast and prostate cancer [1] - It is a potent AKT inhibitor that can suppress all three AKT isoforms (AKT1, AKT2, and AKT3), with its indication for HR+/HER2- breast cancer being second globally only to AstraZeneca's Capivasertib [1] Group 3: Market Potential - Domestic sales peak for LAE002 is estimated to be around 2 billion RMB, while global sales peak can be referenced from Capivasertib [1] - Capivasertib is projected to have sales of 700-800 million USD this year, with a sales peak estimated between 1-2 billion USD [1]