康方生物-B(9926.HK)：AK112展现下一代核心IO基石药物潜力

Core Viewpoint - The company reported a significant increase in product revenue but also faced a substantial loss in net profit due to various factors, including investment losses and rising expenses [1][2]. Financial Performance - In the first half of 2025, the company's product revenue increased by 49.2% year-on-year to 1.4 billion yuan, with total revenue reaching 1.41 billion yuan, and a gross margin of 79.4% [1]. - Research and development expenses rose by 23.0% to 730 million yuan, contributing to a net profit loss of 570 million yuan, which is an increase of 139% compared to the previous period [1]. Capital Raising - In late August 2025, the company raised 3.493 billion HKD by placing 2.355 billion shares at a price of 149.54 HKD per share, resulting in a net cash position of 5.8 billion yuan post-placement [1]. Product Pipeline Progress - The company has made significant advancements in its product pipeline, including approvals for various cancer treatments, with AK104 and AK112 being notable products that have received regulatory approvals and are included in medical insurance [2]. - AK104 has been approved for multiple cancer indications, while AK112 has shown promising results in clinical trials, with plans for further submissions and analyses in the coming years [2]. Valuation and Target Price - The target price has been raised to 144.9 HKD based on a DCF valuation method, assuming a WACC of 10.0% and a perpetual growth rate of 3.0%, indicating a potential upside of 23.4% from the current price [3].