Core Insights - Betaini Group has made significant progress in research and development, with several core products and ingredients validated using a systematic efficacy verification based on 3D skin models [1][4] - The two innovative human-derived recombinant skin models were developed in collaboration with Labskin Creations and will be presented at the European Society for Dermatological Research (ESDR) annual meeting in September 2025, with findings published in the Journal of Investigative Dermatology [1][4] Group 1 - The first model successfully reconstructs a 3D full-thickness human skin model integrating capillary and lymphatic networks, simulating pathological features of inflammatory skin diseases like atopic dermatitis, and has validated its responsiveness to drugs, providing a new predictive tool for studying skin inflammation mechanisms and treatment efficacy [4] - The second model is the first to "assemble" a 3D full-thickness skin that includes subcutaneous fat layers and key immune cells (Langerhans cells), replicating skin responses under environmental stress such as UV damage, offering a more physiologically relevant experimental platform for studying skin barrier function and immune interactions [4] Group 2 - Betaini Group has placed several core products and ingredients, including the second-generation soothing moisturizing cream from the Winona brand, the silver core series compositions, and the high-end brand Aikeman's Meiya Anti-composition, onto these advanced models for efficacy verification, marking a deep integration of product development with cutting-edge in vitro evaluation technologies [4] - Through ongoing collaboration with Labskin Creations, Betaini Group aims to develop exclusive evaluation models that closely resemble the true physiological state of the human body, further enhancing the precision and scientific nature of product development, and providing foundational technical support for continuous innovation in the efficacy skincare sector [4]
贝泰妮集团联合国际科研伙伴发布创新3D皮肤模型 助力产品研发精准化发展