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NetraMark Presents AI-Driven Advances in Precision Psychiatry to Enhance Clinical Trial Designs at Joint Autumn Conference
Globenewswire· 2025-10-29 10:30
Core Insights - NetraMark Holdings Inc. is leveraging its AI technology, NetraAI, to enhance clinical trials in the pharmaceutical industry, particularly for major depressive disorder (MDD) [1][10] Group 1: Presentation Highlights - At the ISCTM Autumn conference and ECNP Congress, NetraMark showcased two significant applications of its technology, focusing on ketamine and escitalopram trials [1][5] - The first presentation demonstrated how NetraAI identified distinct patient responder subgroups in ketamine trials, revealing that ketamine responders had unique baseline characteristics compared to placebo responders [2][3] - The second presentation introduced a novel algorithm that improved predictive accuracy in heterogeneous MDD trials, specifically for escitalopram response, by identifying a compact feature set related to anhedonia and mood [5][6] Group 2: Key Findings - In the ketamine trial, responder subgroups diverged significantly from placebo responders by the second infusion, indicating that ketamine's efficacy is not merely due to functional unblinding [4][8] - NetraAI's analysis in the CAN-BIND trial reduced clinical variables from 718 to 8 key variables, enhancing prediction accuracy and identifying a subgroup of highly predictive responders [9][7] - The technology revealed a genetic signature linked to neuroplasticity, allowing for a 91% accuracy in predicting treatment success when retrained on specific features [17] Group 3: Implications for Clinical Trials - NetraAI's capabilities can help overcome traditional barriers in CNS drug development by improving patient stratification, reducing placebo-related noise, and enhancing predictive modeling [10][12] - The advancements in distinguishing true pharmacologic effects from placebo responses represent a significant step forward in the design and interpretation of psychiatric and CNS trials [11][12] - As precision medicine becomes increasingly important, NetraMark's innovations provide a robust toolkit for pharmaceutical companies to uncover meaningful patient subgroups and accelerate drug development timelines [12][14]
Verizon Reports 3Q 2025 Earnings Reiterates Full-Year Financial Guidance
Globenewswire· 2025-10-29 10:30
Core Insights - Verizon Communications Inc. reported third-quarter 2025 results, indicating a positive trajectory towards achieving full-year financial guidance [1][9] - CEO Dan Schulman emphasized a shift to a customer-first culture and aggressive transformation of the company's operations and financial profile [2] Financial Performance - Earnings per share (EPS) for Q3 2025 was $1.17, up from $0.78 in Q3 2024; adjusted EPS was $1.21 compared to $1.19 in Q3 2024 [7][24] - Total operating revenue reached $33.8 billion, reflecting a year-over-year increase of 1.5% [7] - Consolidated net income for Q3 2025 was $5.1 billion, compared to $3.4 billion in Q3 2024 [7] - Cash flow from operating activities for the first nine months of 2025 was $28.0 billion, up from $26.5 billion in the same period of 2024 [7] - Free cash flow for the first nine months of 2025 was $15.8 billion, an increase from $14.5 billion in 2024 [7] Revenue Segments - Wireless service revenue grew to $21.0 billion in Q3 2025, marking a 2.1% increase year-over-year [7] - Verizon Consumer revenue totaled $26.1 billion in Q3 2025, up 2.9% year-over-year [7] - Total Verizon Business revenue was $7.1 billion in Q3 2025, a decrease of 2.8% year-over-year [11] Subscriber Metrics - Consumer wireless retail postpaid churn was 1.12% in Q3 2025, while wireless retail postpaid phone churn was 0.91% [11] - Verizon delivered 306,000 broadband net additions in Q3 2025, with total broadband connections exceeding 13.2 million, representing an 11.1% increase year-over-year [7][11] - Business reported 110,000 wireless retail postpaid net additions in Q3 2025, including 51,000 postpaid phone net additions [11] Debt and Financial Ratios - Total unsecured debt at the end of Q3 2025 was $119.7 billion, down from $126.4 billion at the end of Q3 2024 [7] - The ratio of unsecured debt to consolidated net income (LTM) was 5.9 times, and net unsecured debt to consolidated adjusted EBITDA ratio was 2.2 times [7][22] Outlook and Guidance - Verizon remains confident in its full-year guidance, expecting capital expenditures to be within or below the previously guided range of $17.5 billion to $18.5 billion [9][12] - The company anticipates total wireless service revenue growth of 2.0% to 2.8% and adjusted EBITDA growth of 2.5% to 3.5% for the full year [12]
PIF-Backed Diriyah Company Awards Parsons $56 million (SAR 210 million) Contract for Design and Construction Supervision in Saudi Arabia
Globenewswire· 2025-10-29 10:30
Core Insights - Parsons Corporation has been awarded a $56 million contract for Phase 2 of the Diriyah project, which is a 5-year engagement aimed at enhancing urban development in Saudi Arabia [1][4] - The Diriyah project is part of Saudi Arabia's Vision 2030, focusing on creating a mixed-use urban destination that integrates traditional Najdi architecture with modern urban planning [3][10] Group 1: Contract Details - The contract involves the design and delivery of parks, open spaces, and over 55 kilometers of streetscape, including streets, footpaths, and civic buildings [2] - This contract represents new work for Parsons Corporation, which has been a partner in various urban development projects in Saudi Arabia since 2017 [4][5] Group 2: Project Significance - Diriyah is historically significant as the birthplace of Saudi Arabia and is home to the UNESCO World Heritage Site, At-Turaif [3][8] - The development aims to create a walkable city for approximately 100,000 residents and accommodate nearly 50 million visits annually [4][9] Group 3: Company Background - Parsons Corporation has over 65 years of experience in Saudi Arabia and currently manages more than 50 active projects, including mega and giga projects [5] - The company specializes in urban development, transport infrastructure, and sustainability, contributing to the Kingdom's economic diversification efforts [6][11]
Constellium Reports Strong Third Quarter 2025 Results; Raises Full Year 2025 Guidance
Globenewswire· 2025-10-29 10:15
Core Insights - Constellium SE reported strong financial results for Q3 2025, with significant increases in revenue, net income, and Adjusted EBITDA compared to Q3 2024 [5][6][21] - The company appointed Ingrid Joerg as the new CEO, effective January 1, 2026, succeeding Jean-Marc Germain, who will retire at the end of 2025 [3][5] - The company raised its guidance for 2025, expecting Adjusted EBITDA to be in the range of $670 million to $690 million and Free Cash Flow to exceed $120 million [3][27] Financial Performance - Q3 2025 shipments reached 373 thousand metric tons, a 6% increase from Q3 2024, with revenue of $2.2 billion, up 20% year-over-year [5][6] - Net income for Q3 2025 was $88 million, compared to $8 million in Q3 2024, while Adjusted EBITDA increased to $235 million, an 85% rise from the previous year [5][6][21] - For the first nine months of 2025, shipments totaled 1.1 million metric tons, up 2% from the same period in 2024, with revenue of $6.2 billion, an 11% increase [7][6] Segment Performance - Aerospace & Transportation (A&T) segment Adjusted EBITDA for Q3 2025 was $90 million, a 67% increase from Q3 2024, driven by higher shipments and favorable pricing [10][11] - Packaging & Automotive Rolled Products (P&ARP) segment Adjusted EBITDA rose to $82 million in Q3 2025, a 14% increase, supported by improved performance at Muscle Shoals [12][14] - Automotive Structures & Industry (AS&I) segment Adjusted EBITDA increased significantly to $33 million in Q3 2025, up 371% from the previous year, despite lower shipments [15][16] Cash Flow and Liquidity - Free Cash Flow for the first nine months of 2025 was $68 million, a significant improvement from $(15) million in the same period of 2024 [23] - Cash flows from operating activities were $271 million for the first nine months of 2025, compared to $240 million in the prior year [24] - As of September 30, 2025, the company had liquidity of $831 million, consisting of $122 million in cash and cash equivalents [26] Outlook and Strategic Developments - The company expects demand trends to remain stable through the end of 2025, benefiting from improved market dynamics [3][27] - Constellium completed the divestment of its Nanjing Automotive Structures plant in August 2025, indicating a strategic shift in operations [29]
FLSmidth & Co. A/S major shareholder announcement
Globenewswire· 2025-10-29 10:07
COMPANY ANNOUNCEMENT NO. 36-2025 FLSmidth & Co. A/S 29 October 2025 Copenhagen, Denmark FLSmidth & Co. A/S (“FLSmidth” or the “Company”) hereby announces the following notification received pursuant to section 39 of the Danish Capital Markets Act from Société Générale S.A. regarding its holdings of financial instruments relating to shares in FLSmidth. On 28 October 2025, Société Générale S.A. informed FLSmidth that, as of 22 October 2025, its aggregate holding of financial instruments with a similar economi ...
Katapult to Announce Third Quarter 2025 Financial Results on November 12, 2025
Globenewswire· 2025-10-29 10:00
PLANO, Texas, Oct. 29, 2025 (GLOBE NEWSWIRE) -- Katapult Holdings, Inc. (NASDAQ: KPLT), an e-commerce-focused financial technology company, today announced it will release its third quarter 2025 financial results before the market opens on Wednesday, November 12, 2025. The company will host a conference call and webcast to discuss these results at 8:00 AM ET that same day. A live audio webcast of the conference call will be available on the Katapult Investor Relations website at http://ir.katapultholdings.c ...
BillionToOne Announces Launch of Initial Public Offering Roadshow
Globenewswire· 2025-10-29 10:00
MENLO PARK, Calif., Oct. 29, 2025 (GLOBE NEWSWIRE) -- BillionToOne, Inc., a molecular diagnostics company with a mission to create powerful and accurate tests that are accessible to all, today announced that it has launched the roadshow for its proposed initial public offering of 3,846,000 shares of its Class A common stock. In addition, BillionToOne intends to grant the underwriters a 30-day option to purchase up to an additional 576,900 shares of its Class A common stock at the initial public offering pri ...
Armada Hoffler Announces 12,000-Square-Foot Atlantic Union Bank Lease at Town Center of Virginia Beach
Globenewswire· 2025-10-29 10:00
New lease immediately backfills space and brings Town Center office occupancy to 99%VIRGINIA BEACH, Va., Oct. 29, 2025 (GLOBE NEWSWIRE) -- Armada Hoffler (NYSE: AHH) today announced that Atlantic Union Bank has signed a full floor lease for approximately 12,000 square feet at One Columbus Center, located in the heart of Town Center of Virginia Beach. The new lease represents an immediate backfill of recently available space at a nearly 7% spread over the prior tenant’s lease. Armada Hoffler’s office portfol ...
OMS Energy Technologies Inc. Inks Technical Service Partner Contract with a Major Thai Oil and Gas Operator
Globenewswire· 2025-10-29 10:00
Core Insights - OMS Energy Technologies Inc. is expanding its partnership with a major oil and gas operator in Thailand, reflecting the operator's confidence in OMS Thailand's technical capabilities and service quality [1][3] Company Overview - OMS Energy Technologies Inc. is a growth-oriented manufacturer specializing in surface wellhead systems (SWS) and oil country tubular goods (OCTG) for the oil and gas industry, serving both onshore and offshore operators [4] - The company operates 11 strategically located manufacturing facilities across the Asia Pacific, Middle Eastern, and North African regions, ensuring rapid response and customized solutions [4] Service Expansion - OMS Thailand has been awarded a Technical Service Partner Contract, which includes technical consultancy, gauging management, and hardware services, indicating a deepening collaboration with a key player in Thailand's oil and gas sector [1][3] - The facilities in Songkhla and Sattahip have over 20 and 10 years of service experience, respectively, and are fully licensed to support the OCTG sector with various services [2] Operational Excellence - OMS Thailand is recognized as one of Thailand's largest single-operator machine shops, meeting stringent performance and vendor selection criteria through quality control and responsive maintenance [2] - The company emphasizes a culture of precision, innovation, and reliability, which is crucial for maintaining its competitive edge in the industry [3]
Amplify Energy Announces Divestiture of East Texas Assets
Globenewswire· 2025-10-29 10:00
Core Viewpoint - Amplify Energy Corp. is executing a strategic divestiture of its East Texas assets, expecting a total consideration of $127.5 million, which will enhance its balance sheet and allow the company to focus on higher upside opportunities [1][2][3]. Group 1: Transactions Overview - The company has sold its remaining interest in the Haynesville basin for net proceeds of $5.5 million, which closed on October 24, 2025 [6]. - A definitive agreement has been made to sell the remaining Haynesville and Cotton Valley interests for a contract price of $122 million, expected to close by the end of Q4 2025 [6]. Group 2: Strategic Implications - The divestiture aligns with the company's strategic plan to simplify its portfolio and enhance liquidity, with proceeds aimed at debt reduction [2][3]. - Following the completion of the East Texas transaction, the company anticipates a significant reduction in general and administrative costs [2]. Group 3: Leadership Insights - The CEO of Amplify Energy emphasized the importance of this transaction in unlocking value from the company's most promising areas, specifically Beta and Bairoil [3]. - The CEO also acknowledged the efforts of the team in executing these transactions while maintaining safe and efficient operations [3]. Group 4: Company Profile - Amplify Energy Corp. is an independent oil and natural gas company focused on the acquisition, development, and production of oil and natural gas properties, primarily in Southern California, the Rockies, and Oklahoma [4].