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Novartis presents Rhapsido® (remibrutinib) data at AAAAI, showing potential beyond chronic spontaneous urticaria (CSU)
Globenewswire· 2026-02-23 06:15
Core Insights - Novartis will present data on Rhapsido (remibrutinib), a selective oral Bruton's tyrosine kinase inhibitor, at the AAAAI Annual Meeting, focusing on its use in chronic spontaneous urticaria (CSU) and potential for peanut allergy treatment [1][2][3] Group 1: Clinical Data and Trials - New analyses from Phase III REMIX-1 and REMIX-2 trials will be presented, highlighting Rhapsido's impact on disease control and early symptom relief in CSU [2][6] - The first Phase II data on remibrutinib for IgE-mediated peanut allergy will be featured, with plans for a Phase III program in food allergy set for 2026 [2][3][6] - Positive topline results from the CIndU Phase III RemIND trial were announced, with FDA submission for symptomatic dermographism completed in Q4 2025 [4] Group 2: Regulatory and Market Potential - Regulatory reviews for remibrutinib in CSU are ongoing in regions including the European Union and Japan, indicating a strong commitment to expanding its market presence [3][4] - Novartis aims to address unmet needs in immune-mediated diseases, emphasizing the importance of innovative therapies for patients with limited alternatives [3][4] Group 3: Presentation Details - Accepted abstracts for presentation at the AAAAI include studies on the efficacy and safety of remibrutinib for peanut allergy and analyses from the REMIX studies on CSU [5][6] - Specific presentation times and formats are outlined, including oral and poster sessions scheduled from February 27 to March 1, 2026 [5][6]
argenx to Present at TD Cowen 46th Annual Healthcare Conference
Globenewswire· 2026-02-23 06:00
Core Viewpoint - argenx is actively engaging in the healthcare sector by participating in conferences to discuss advancements in immunology and its commitment to treating severe autoimmune diseases [1]. Company Overview - argenx is a global immunology company focused on improving the lives of individuals suffering from severe autoimmune diseases [3]. - The company collaborates with leading academic researchers through its Immunology Innovation Program (IIP) to translate immunology breakthroughs into a portfolio of novel antibody-based medicines [3]. - argenx has developed and is commercializing the first approved neonatal Fc receptor (FcRn) blocker, exploring its potential across multiple serious autoimmune diseases while advancing several earlier-stage experimental medicines [3]. Event Participation - Karen Massey, the Chief Operating Officer of argenx, will participate in a fireside chat at the TD Cowen 46 Annual Healthcare Conference on March 2 at 11:50 a.m. ET [1]. - A live webcast of the presentation will be available on the Investors section of the argenx website, with a replay accessible for approximately 30 days following the event [2].
WISeKey to Relocate Its Geneva Headquarters to Pont-Rouge in August 2026
Globenewswire· 2026-02-23 06:00
Core Viewpoint - WISeKey International Holding Ltd is relocating its headquarters from Geneva to Pont-Rouge in August 2026, aiming to enhance its position in the digital and quantum technology sectors [3][12]. Group 1: Relocation Details - The new headquarters will be situated in Pont-Rouge, a modern and sustainable business district completed in 2023, which offers exceptional connectivity and a vibrant ecosystem for innovation [4][5]. - Pont-Rouge spans over 100,000 m² and includes premium office facilities, co-working spaces, and iconic buildings, already hosting major firms like EY and KPMG [5]. Group 2: Geneva Quantum Center of Excellence - The headquarters will house the Geneva Quantum Center of Excellence, aimed at establishing Geneva as a global leader in applied quantum technologies [6][12]. - The Center will integrate various technologies including quantum computing, cybersecurity, and AI, creating a comprehensive ecosystem for industrial applications [6][12]. Group 3: SEALSQ Quantum Computer Hub - The Quantum Computer Hub, operated by WISeKey's subsidiary SEALSQ Corp, will focus on practical quantum architectures for secure integration into critical infrastructures across various sectors [7]. - The hub will emphasize hybrid quantum/classical computing models and secure interfaces between quantum processors and embedded systems [8]. Group 4: SEALSQ Quantum Fund - The SEALSQ Quantum Investment Fund, with over USD 100 million, aims to build a root-to-quantum vertical stack and accelerate the deployment of secure quantum technologies in the US and Europe [10]. - The fund's strategy seeks to eliminate fragmentation in the quantum value chain, promoting sovereign and certifiable quantum solutions [11]. Group 5: Strategic Commitment - The relocation and establishment of the Geneva Quantum Center of Excellence reflect WISeKey and SEALSQ's commitment to technological sovereignty in Europe and the development of trusted digital infrastructures [12][16].
SEALSQ and WISeKey to Relocate Geneva Headquarters to Pont-Rouge in August 2026
Globenewswire· 2026-02-23 06:00
Core Insights - SEALSQ Corp and WISeKey International Holding Ltd are relocating their Geneva headquarters to Pont-Rouge in August 2026, reflecting their rapid expansion and ambition in digital and quantum technologies [3][12] - The new headquarters will host the Geneva Quantum Center of Excellence, aimed at establishing Geneva as a global reference for applied quantum technologies [6][12] Company Overview - SEALSQ specializes in developing and selling semiconductors, PKI, and post-quantum technology hardware and software products [3][13] - The company is focused on creating post-quantum semiconductors that provide robust protection for sensitive data across various applications, including healthcare, defense, and IoT [14][17] Quantum Center of Excellence - The Geneva Quantum Center of Excellence will serve as a deep-tech convergence platform, integrating quantum computing, post-quantum cybersecurity, and other advanced technologies [6][10] - The center will feature a live demonstration environment showcasing the interoperability of the group's technologies across different domains [9] Quantum Investment Fund - The SEALSQ Quantum Investment Fund, with over USD 100 million, aims to build a root-to-quantum vertical stack and accelerate the deployment of secure quantum technologies in the U.S. and Europe [10][11] - The fund's strategy focuses on eliminating fragmentation between research, hardware, and deployment to create scalable quantum solutions [11] Strategic Commitment - The relocation and establishment of the Geneva Quantum Center of Excellence highlight SEALSQ and WISeKey's commitment to technological sovereignty in Europe and the development of trusted digital infrastructures [12][16]
AGIBOT Accelerates Singapore Engagement with Diversified Approaches and Deployment-Focused Initiatives
Globenewswire· 2026-02-23 06:00
Core Insights - AGIBOT is expanding its presence in Singapore following its market entry in 2025, focusing on understanding local industry needs and exploring collaboration opportunities [1][2][10] Group 1: Market Engagement - AGIBOT participated in a Chinese New Year event on February 11, 2026, showcasing its robotics portfolio, including a robotic dog demonstration, to local business and professional communities [2][4] - The company engaged in a blessing ceremony at Sentosa on February 17, 2026, and showcased humanoid robotics in a hospitality environment, allowing guests to observe system design and mobility features [3][7] Group 2: Strategic Collaborations - AGIBOT featured its robotics technology at Changi Airport Terminal 5 in collaboration with Certis Group, assessing robotics integration in high-security and high-traffic environments [5] - The company is exploring diversified market approaches, including joint ventures, leasing collaborations, and establishing a regional experience center for technical demonstrations and enterprise training [9] Group 3: Deployment Strategy - AGIBOT is adopting a phased deployment strategy in Singapore, focusing on controlled testing, operational feedback, and local collaboration to ensure long-term sustainability of humanoid robotics applications [8] - The company shipped over 5,100 humanoid robots globally in 2025, ranking first in the world, reflecting its industrial-scale production capability and expanding international footprint [6]
Cygnus targets resource growth with start of new drilling and geophysics programs
Globenewswire· 2026-02-22 23:14
Core Insights - Cygnus Metals Limited is initiating extensive exploration programs at its Chibougamau Copper-Gold Project in Quebec, aiming to grow resources and drive shareholder value through resource growth [6][7][8] - The company has reported a 29% increase in resources last year and is optimistic about further exploration results [4][8] Exploration Strategy - The exploration campaign focuses on extending known mineralization, drilling defined targets, and identifying new prospects [1][6] - Key areas of focus include brownfields exploration at Cedar Bay and Golden Eye, with ongoing Downhole Electromagnetics (DHEM) to identify follow-up targets [7][8][9] Resource Estimates - Current resource estimates for the Chibougamau project stand at 6.4 million tonnes (Mt) at 3% CuEq for 193,000 tonnes (kt) CuEq (Measured & Indicated) and 8.5 Mt at 3.5% CuEq for 295 kt CuEq (Inferred) [8][28] - Specific drilling results include 28.9m at 2.5g/t AuEq and 10.6m at 4.1g/t AuEq from recent exploration at Cedar Bay [8][12] Drilling Activities - Drilling has commenced at Golden Eye with three rigs to extend the resource below the current depth of 450m, where the resource is currently defined at 0.5 Mt at 5.6g/t AuEq [10][11] - At Joe Mann, a detailed Induced Polarisation (IP) survey is underway to identify drill targets, with historical intersections showing significant gold potential [11][13] Infrastructure and Partnerships - The Chibougamau area has established infrastructure, including a processing facility with a capacity of 900,000 tonnes per annum, which is the only facility within a 250 km radius [11][12] - Drilling at the Gwillim prospect will be co-funded by Alamos Gold, which has a market capitalization of approximately C$25 billion [11][12]
Dyne Therapeutics Announces Upcoming Presentations Across Neuromuscular Pipeline at 2026 MDA Clinical & Scientific Conference
Globenewswire· 2026-02-22 21:00
Core Insights - Dyne Therapeutics is set to present five key presentations at the 2026 Muscular Dystrophy Association Clinical & Scientific Conference, showcasing advancements in their neuromuscular disease programs, particularly in Duchenne muscular dystrophy (DMD), myotonic dystrophy type 1 (DM1), and Pompe disease [1][2]. Group 1: Presentation Highlights - The company will present new long-term data from the DELIVER trial in DMD, indicating potential preservation of cardiopulmonary function [2][4]. - A robust Phase 3 trial design for z-basivarsen in DM1 will be discussed, which is anticipated to be field-defining [2][3]. - Dyne's pipeline demonstrates strength through the FORCE™ platform, which is validated by clinical data showing functional improvements across various muscle groups [2][4]. Group 2: Oral and Poster Presentations - Oral presentations will include significant findings on z-rostudirsen's impact on dystrophin protein levels and functional improvements in DMD [3]. - The design of a global Phase 3 trial for z-basivarsen in DM1 will be presented, along with preclinical data for DYNE-401 targeting Pompe disease [3][4]. - Poster presentations will feature late-breaking data on z-rostudirsen's long-term clinical outcomes and new analyses from the DELIVER trial [4][5]. Group 3: Conference Details - The conference will take place from March 8-11, 2026, in Orlando, FL, and virtually, with all presentations available on Dyne's website [1][6]. - A symposium titled "Functional improvement: Moving beyond dystrophin in DMD" is scheduled for March 9, 2026 [6].
Canacol Energy Announces Leadership Change and Independent Director Appointment
Globenewswire· 2026-02-22 16:41
Core Viewpoint - Canacol Energy Ltd. is undergoing a leadership change to enhance its restructuring efforts, with the appointment of interim co-CEOs and an independent director to the board, aimed at positioning the company for success during its restructuring process under the Companies' Creditors Arrangement Act (CCAA) [1][2][4]. Leadership Changes - Mr. Jason Bednar and Mr. Ravi Sharma have been appointed as Interim Co-Chief Executive Officers while retaining their roles as Chief Financial Officer and Chief Operating Officer, respectively [2]. - Dr. Charle Gamba has departed from his role as President and Chief Executive Officer, with the board expressing gratitude for his contributions [3]. Board Appointments - Mr. Peter Laurinaitis has been appointed as an independent director, bringing extensive experience in financial restructuring and corporate turnarounds [4][5]. - Laurinaitis has 30 years of transactional experience and has held significant roles in restructuring at firms like PJT Partners and Blackstone [6]. Company Background - Canacol Energy Ltd. is focused on natural gas exploration and production, primarily operating in Colombia [9].
nVent Postpones Investor Day due to Weather-related State of Emergency Declared in New York City Metropolitan Area
Globenewswire· 2026-02-22 16:04
Core Viewpoint - nVent Electric plc has postponed its Investor Day originally scheduled for February 24, 2026, due to a state of emergency in the New York metropolitan area caused by an impending winter storm [1][2]. Company Overview - nVent is a global leader in electrical connection and protection solutions, focusing on enabling safer systems and ensuring a secure world through its innovative electrical solutions [3]. - The company designs, manufactures, markets, installs, and services high-performance products that protect sensitive equipment, buildings, and critical processes [3]. - nVent's product portfolio includes well-known brands such as nVent CADDY, ERICO, HOFFMAN, ILSCO, SCHROFF, and TRACHTE, with a history spanning over 100 years [4]. Investor Relations - The company is currently evaluating scheduling options for the postponed Investor Day and will issue a formal invitation once the new date and location are finalized [2]. - The postponement is strictly due to weather-related logistics and does not indicate any changes in the company's operations, financial performance, or outlook [2].
MoonLake Announces Positive Topline Results from its Phase 2 Clinical Trial of Sonelokimab in Axial Spondyloarthritis and Reports 2025 Financial Results
Globenewswire· 2026-02-22 16:00
Group 1 - MoonLake Immunotherapeutics announced topline results from the S-OLARIS Phase 2 trial of sonelokimab (SLK) in patients with axial spondyloarthritis (axSpA), demonstrating significant clinical benefits [2][5][6] - In the S-OLARIS trial, 81% of patients treated with SLK achieved an ASAS40 response at Week 12, indicating a clinically meaningful improvement [2][5] - The trial also showed over 80% of patients achieved a clinically important improvement as per ASDAS-CRP score, with significant reductions in inflammation and osteoblast activity observed through PET imaging [2][5][6] Group 2 - MoonLake reported financial results for Q4 and the year ended December 31, 2025, with cash and equivalents totaling $394 million, expected to fund operations into the second half of 2027 [7] - Research and development expenses for Q4 2025 were $56 million, down from $60.6 million in the previous quarter, while general and administrative expenses decreased to $9.2 million from $10.8 million [7] - The company amended its debt facility with Hercules Capital, drawing down $25 million, with up to $400 million in non-dilutive funds available for future needs [7] Group 3 - An Investor Day webcast is scheduled for February 23, 2026, where the company will present the S-OLARIS data and discuss upcoming milestones, including the Type B FDA Meeting outcomes for hidradenitis suppurativa [8][12] - The company is pursuing multiple indications for sonelokimab, including hidradenitis suppurativa, psoriatic arthritis, and palmoplantar pustulosis, with significant market opportunities projected [11][27][29]