Core Insights - KOMZIFTI (ziftomenib) is the first and only once-daily oral menin inhibitor approved by the FDA for adults with relapsed or refractory acute myeloid leukemia (AML) with a susceptible NPM1 mutation, now commercially available in the U.S. [1][2] - The drug has been included in the National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines as a Category 2A recommended treatment option for this patient population [1][3] Company Overview - Kura Oncology, Inc. is a biopharmaceutical company focused on precision medicines for cancer treatment, with KOMZIFTI being a key product in its pipeline [19] - Kyowa Kirin Co., Ltd. is a global specialty pharmaceutical company with a long history in drug discovery and biotechnology innovation, collaborating with Kura on the commercialization of KOMZIFTI [20] Clinical Data - KOMZIFTI received full FDA approval on November 13, 2025, based on the KOMET-001 clinical trial, which demonstrated a 21.4% complete response (CR) or complete response with partial hematologic recovery (CRh) rate and a median duration of response of 5 months [2] - The clinical trial involved 112 patients with R/R AML and NPM1 mutation, with differentiation syndrome (DS) occurring in 26% of patients [8][14] Treatment Guidelines - The inclusion of KOMZIFTI in the NCCN Guidelines highlights its potential impact on patients with R/R NPM1-mutated AML and reflects the commitment to patient access [3] - KOMZIFTI is also being developed for front-line treatment of AML with various mutations, indicating its potential to benefit a broader patient population [5] Safety Information - KOMZIFTI has a boxed warning for differentiation syndrome, which can be fatal, and requires monitoring and management protocols [6][7] - Adverse reactions reported in clinical trials include serious reactions in 79% of patients, with the most common being infections and differentiation syndrome [14][16]

Core Viewpoint - Peoples Financial Corporation has declared a regular semi-annual cash dividend of $0.18 per common share, payable on December 12, 2025, to shareholders of record as of December 8, 2025 [1][2]. Company Overview - Founded in 1896, Peoples Financial Corporation has total assets of $758 million as of September 30, 2025, and operates 18 bank facilities along the Mississippi Gulf Coast [3]. - The Peoples Bank offers a comprehensive range of retail and commercial banking services, along with trust and investment services since 1936 [3]. Stock Information - Peoples Financial Corporation's common stock is listed on the OTCQX Best Market under the symbol PFBX [4].

Core Points - Avante Corp Inc. will host an investor webinar on December 1, 2025, to discuss its fiscal second quarter results for the period ending September 30, 2025 [1] - The webinar will be led by Emmanuel Mounouchos, CEO, and Raj Kapoor, CFO of Avante [1] Webinar Details - The webinar is scheduled for December 1, 2025, at 10:00 am ET (7:00 am PT) [2] - Dial-in numbers for local connections in Vancouver and Toronto are provided, along with a confirmation number for participants [2] Company Overview - Avante Corp Inc. is a Toronto-based provider of technology-enabled security solutions for residential and commercial clients [3] - The company aims to deliver high-level security globally, focusing on high-net-worth families and corporations through advanced detection methods [3] - Avante has developed a diversified security platform and is pursuing organic growth and strategic acquisitions to expand its portfolio of security businesses [3]

CALGARY, Alberta, Nov. 25, 2025 (GLOBE NEWSWIRE) -- Integral Metals Corp. (CSE: INTG | FSE: ZK9) (the “Company” or “Integral”) is pleased to announce that it has fully repaid, in cash, the secured convertible debt it had assumed in late June 2025 (please see news release dated June 24, 2025) by paying to the lender thereof the amount of US$1,000,000 plus applicable interest. On Behalf of the Board Directors Paul SparkesChief Executive Officer 825-414-3163info@integralmetals.com ABOUT INTEGRAL METALS CORP. I ...

Core Insights - Methanex Corporation has appointed Don Marchand to its Board of Directors, effective December 1, 2025 [1][4]. Company Overview - Methanex is the world's largest supplier of methanol and is publicly traded on the Toronto Stock Exchange under the symbol "MX" and on the Nasdaq under "MEOH" [5]. Leadership Background - Don Marchand has nearly four decades of experience in finance and energy infrastructure, having held significant roles at TC Energy, including Executive Vice President and Chief Financial Officer from 2010 to 2021 [2]. - Marchand holds a Bachelor of Commerce from the University of Manitoba and is a Chartered Accountant and Chartered Financial Analyst, with memberships in several professional organizations [3]. Strategic Importance - Doug Arnell, Chair of the Board at Methanex, expressed enthusiasm about Marchand's extensive executive expertise in financial functions and knowledge of the North American energy sector, indicating that these will be valuable assets to the Board [4].

Core Insights - Urbanfund Corp. has filed its financial statements for the three and nine months ended September 30, 2025, along with the corresponding Management's Discussion and Analysis [1] Business Overview and Strategy - Urbanfund Corp. is listed on the TSX Venture Exchange under the symbol UFC and focuses on investing in Canadian real estate, including both residential and commercial properties [2] - The company's assets are located in various cities across Ontario, Quebec, and Nova Scotia [2] Operational Highlights - Urbanfund's strength lies in its ability to attract partners with proven expertise in residential and commercial development [3] Results from Operations - For the three months ended September 30, 2025, rental revenue was CAD 2,154,357, an increase from CAD 2,090,060 in the same period of 2024 [7] - Income before taxes for the same period was CAD 2,614,412, compared to CAD 2,101,886 in 2024 [7] - Net income attributable to shareholders for the three months ended September 30, 2025, was CAD 2,223,823, up from CAD 1,516,042 in 2024 [10] Selected Quarterly Information - During the nine months ended September 30, 2025, Urbanfund sold four commercial units at 1040 Martin Grove Road for total sales proceeds of CAD 1,685,124, compared to five units for CAD 2,243,194 in 2024 [6] - At 270-330 Esna Park Drive, 18 commercial units were sold for CAD 3,354,897, a significant increase from three units for CAD 677,706 in 2024 [6] Financial Position - As of September 30, 2025, total assets were CAD 156,323,215, compared to CAD 155,604,351 at the end of 2024 [7] - Total investment properties amounted to CAD 109,476,000, up from CAD 108,843,000 in 2024 [7] - Total mortgages payable were CAD 54,337,105, slightly down from CAD 55,506,091 in 2024 [7] Liquidity and Capital Resources - Urbanfund's liquidity as of September 30, 2025, was CAD 10,412,857, representing 19.1% of its total debt of CAD 54,393,462 [14] - The company expects to meet all obligations, including dividends to shareholders and capital expenditures, through cash flows generated from operating activities [13] Dividend Reinvestment Plan - Urbanfund has a Dividend Reinvestment Plan (DRIP) that allows shareholders to reinvest dividends to acquire additional shares at a discount [16] - The annual dividend rate was increased to CAD 0.05 per common share, a 67% increase from the previous year [17] Non-IFRS Measures - Funds from Operations (FFO) for the three months ended September 30, 2025, were CAD 1,601,386, down from CAD 1,933,384 in 2024 [9] - Adjusted Cash Flows from Operations (ACFO) for the same period were CAD 1,966,346, compared to CAD 3,032,313 in 2024 [11]

Core Insights - ROHM Semiconductor has developed a new 100V power MOSFET, RS7P200BM, which features industry-leading Safe Operating Area (SOA) in a compact 5060-size package, suitable for hot-swap circuits in AI servers and industrial power supplies [1][3]. Industry Demand and Trends - The rapid adoption of AI technologies has heightened the need for stable operation and improved power efficiency in servers, particularly those utilizing generative AI and high-performance GPUs [2]. - The shift towards 48V power supplies is driven by the demand for better power conversion efficiency and energy conservation in data centers and AI servers [2]. Product Features and Specifications - The RS7P200BM achieves a low on-resistance (RDS(on)) of 4.0mΩ under specific conditions, while maintaining a wide SOA of 7.5A at a pulse width of 10ms and 25A at 1ms, which enhances power supply efficiency and reduces cooling loads [4]. - The new product is designed for high-density mounting, outperforming the previously released RY7P250BM in terms of size and efficiency [3][12]. Production and Availability - Mass production of the RS7P200BM commenced in September 2025, and it is available for online purchase through distributors like DigiKey and Mouser [5]. Future Developments - ROHM plans to continue expanding its product lineup for 48V power supplies, aiming to enhance energy efficiency and reliability in server systems and reduce power loss in data centers [6]. Application Examples - The RS7P200BM is suitable for various applications, including 48V system AI servers, industrial power supplies, battery-powered industrial equipment, and emergency power systems [7]. Brand Information - EcoMOS™ is ROHM's brand of silicon power MOSFETs designed for energy-efficient applications across various sectors, including home appliances and automotive systems [7].

Currently targeting strike extension of the gold-bearing veinsTORONTO, Nov. 25, 2025 (GLOBE NEWSWIRE) -- Q-Gold Resources Ltd. (TSXV: QGR; OTCQB: QGLDF) ("QGold" or the "Company") is pleased to announce commencement of its second diamond drilling campaign of 2025 at the Mine Centre Gold Project in northwestern Ontario. Rodren Drilling of Winnipeg, Manitoba has again been engaged as the drilling contractor. Critical Discoveries, a prominent geological consulting firm, also based in Winnipeg, Manitoba has bee ...

Core Viewpoint - Johnson Outdoors Inc. is set to release its financial results for the Fiscal 2025 fourth quarter on December 12, 2025, before market opening, followed by a conference call to discuss the results and provide company updates [1]. Company Overview - Johnson Outdoors Inc. is a leading global innovator in outdoor recreation equipment and technologies, aiming to inspire more people to enjoy the outdoors [3]. - The company designs, manufactures, and markets a diverse portfolio of consumer-preferred brands across four categories: Watercraft Recreation, Fishing, Diving, and Camping [3]. - Iconic brands under Johnson Outdoors include Old Town canoes and kayaks, Carlisle paddles, Minn Kota trolling motors, Cannon downriggers, Humminbird marine electronics, SCUBAPRO dive equipment, and Jetboil outdoor cooking systems [3]. Conference Call Details - A live listen-only webcast of the conference call will be available on Johnson Outdoors' homepage, with a replay accessible for 30 days in the Investor section of the website [2].

Core Points - Abitibi Metals Corp. has entered into an agreement with underwriters to raise approximately C$10 million through the sale of 12,300,000 charity flow-through common shares at C$0.57 each and 8,580,000 hard dollar common shares at C$0.35 each [1][3] - The offering is expected to close around December 16, 2025, pending necessary regulatory approvals [2] - Proceeds from the charity flow-through common shares will be used for the advancement of the B26 Polymetallic Deposit, while net proceeds from the common shares will be allocated for general corporate purposes [3] Company Overview - Abitibi Metals Corp. focuses on acquiring and exploring mineral properties in Quebec, emphasizing high-quality base and precious metal assets with significant growth potential [5]