Key Takeaways Esperion named ESP-2001 its new preclinical candidate for primary sclerosing cholangitis.ESP-2001 was discovered with Evotec and has shown liver injury reduction in preclinical studies.Esperion will hold exclusive global rights to develop and commercialize ESP-2001.Esperion Therapeutics (ESPR) announced that it has nominated ESP-2001, a highly specific allosteric ATP citrate lyase (“ACLY”) inhibitor, as its new preclinical development candidate for the treatment of primary sclerosing cholangit ...

This article looks at the 14 Best Big Name Stocks to Invest in Right Now.By the term Big Name, we denote stocks that are industry leaders with a significant presence on the stock market. These firms are typically characterized by their large market capitalization, strong brand recognition, and stable financials.The S&P 500 Index, which tracks leading U.S.-listed companies, is up 13.42% year-to-date, building on the 24.2% and 23.31% returns in 2023 and 2024, respectively. The broad market index has hit recor ...

Pawel Kacperek/iStock via Getty Images Balance Continues to Deliver Results Market Overview U.S. equities continued their upward momentum in the third quarter, with the S&P 500 Index up 8.1% and the benchmark Russell 3000 Index increasing 8.2%. Investor optimism was fueled by better-than-feared tariff outcomes, the passing of the One Big Beautiful Bill Act in July, anticipated interest rate cuts — the Federal Reserve delivered with a 25-bps cut in September and signaled further easing — and robust corpo ...

Autopay feels like one of life’s little luxuries. Set it up once, and your bills are forever paid on time, late fees vanish, and your to-do list gets shorter. For most recurring expenses, it’s a no-brainer — why not make life easier? Find Out: 4 Secrets of the Truly Wealthy, According To Dave Ramsey For You: 8 Common Mistakes Retirees Make With Their Social Security Checks Here’s the twist, though: Not every bill should be set up for autopay. Some expenses are better managed manually, especially when the ...

Delinquencies remain steady at 1.3%, while credit quality improved, with average FICO scores up 15 points following the Platinum Card refresh.American Express posted third-quarter earnings results Friday (Oct. 17) that indicated strong growth in card spending, particularly among consumers in the Generation Z and millennial cohorts.By completing this form, you agree to receive marketing communications from PYMNTS and to the sharing of your information with our sponsor, if applicable, in accordance with our P ...

About this content About Sean Mason Sean Mason is a Senior Journalist at Proactive, having researched and written about Canadian and US equities for 20 years. Sean graduated from the University of Toronto with a BA in history and economics and has also passed the Canadian Securities Course. He previously worked at Investors Digest of Canada, Stockhouse, and SmallCapPower.com. Read more About the publisher Proactive financial news and online broadcast teams provide fast, accessible, informative and action ...

Key Takeaways Centrus Energy leads in HALEU production with a $3.6B backlog and expansion plans at its Ohio plant.Cameco posted 47% revenue growth, fueled by uranium sales and stronger earnings from Westinghouse.Both benefit from nuclear momentum, but Centrus Energy's valuation and HALEU edge make it more appealing.Centrus Energy (LEU) and Cameco (CCJ) are both well-positioned to benefit from the accelerating global shift toward nuclear energy. Centrus Energy supplies nuclear fuel and services for the nucle ...

Key Takeaways Regions Financial posted Q3 EPS of $0.63, which topped estimates and rose from $0.57 last year.Higher net interest and non-interest income drove revenues up 7% year over year to $1.92 billion.Improved efficiency and lower credit provisions supported results, despite lower loans and deposits.Regions Financial Corporation’s (RF) third-quarter 2025 adjusted earnings per share of 63 cents beat the Zacks Consensus Estimate of 60 cents. This compares favorably with earnings of 57 cents per share in ...

Core Insights - Upstart Holdings (UPST) is expanding its services beyond personal loans, leveraging its AI-powered platform to enter new markets such as auto loans, home equity, and small-dollar credit, with these segments accounting for nearly 20% of new borrowers in Q2 2025 [1][8] - The company has more than doubled its revenues year over year and achieved GAAP profitability earlier than expected [1] Auto Lending - Auto loan originations surged 87% sequentially to $114 million in Q2 2025, driven by the adoption of Upstart's Auto Retail software among car dealerships [2][8] - A focus on simplifying financing has led to increased dealer-driven loan requests and finalized agreements [2] Home Equity - The home equity segment has seen a nearly ninefold increase in originations year over year, reaching $68 million, facilitated by advancements in instant property verification technology [3][8] - This technology allows borrowers to complete ownership and income checks in under a minute, streamlining the traditionally slow HELOC process [3] Small-Dollar Loans - Small-dollar "relief" loans have increased by 40% sequentially as Upstart tests its AI models across a broader borrower base [4] - The latest underwriting model, Model 22, has improved accuracy and conversion rates, supporting the growth of these new verticals [4] Diversification Strategy - Upstart plans to move most Auto and Home loans off its balance sheet by late 2025, relying on third-party funding and partnerships with banks and credit unions to support this diversification [4] Industry Comparisons - Other fintech companies like PayPal and Intuit are also diversifying their revenue streams, with PayPal expanding into merchant solutions and consumer credit, while Intuit has developed a full financial ecosystem [5][6] Valuation and Performance - Upstart's shares have increased by 16.8% over the past six months, although this performance lags behind the broader industry and the S&P 500 [7] - The current forward 12-month Price/Sales (P/S) ratio for Upstart is 3.77X, which is above the industry average of 3.52X, indicating that the shares may be overvalued [9] Earnings Estimates - The Zacks Consensus Estimates for EPS for the full years 2025 and 2026 have been revised downward, but they still indicate significant year-over-year increases [10]

Key Takeaways American Express posted Q3 EPS of $4.14, beating estimates and rising 19% YoY.Network volumes hit $479.2B, up 9% YoY, driven by higher U.S. consumer spending and card usage.Revenues climbed 11% YoY to $18.4B, aided by robust card fee growth and strong Gen-Z and Millennial demand.American Express Company (AXP) reported third-quarter 2025 earnings per share (EPS) of $4.14, which beat the Zacks Consensus Estimate by 4.6%. The bottom line climbed 19% year over year.Total revenues, net of interest ...