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康诺亚-B:两款双抗授权出海,核心管线进展顺利

Investment Rating - The report maintains a "Buy" rating for the company, considering its core pipeline is nearing approval and the progress of its R&D pipeline is positive [3] Core Views - The company has entered into a licensing agreement with Belenos Biosciences, granting exclusive rights for the research, development, registration, production, and commercialization of two bispecific antibodies (CM512 and CM536) outside Greater China [2] - The company will receive an upfront payment of $15 million and a 30.01% equity stake in Belenos, with potential additional payments of up to $170 million based on development, regulatory, and commercial milestones [2] - The company's R&D pipeline is differentiated and progressing well, with CM310 (IL4Rα) expected to be approved in China for adult moderate-to-severe atopic dermatitis this year, and other indications such as chronic rhinosinusitis with nasal polyps and seasonal allergic rhinitis also progressing [2] - CMG901 (CLDN 18.2 ADC) has global rights granted to AstraZeneca, with a global Phase III trial for second-line gastric cancer completed in April 2024 [2] - Other pipeline candidates, including CM326 (TSLP), CM338 (MASP-2), CM313 (CD38), and several CD3 bispecific antibodies, are also advancing through clinical trials [2] Financial Forecasts and Valuation - The company's revenue is projected to be RMB 224 million, RMB 532 million, and RMB 1.216 billion for 2024, 2025, and 2026, respectively [3] - Using a DCF valuation method with a perpetual growth rate of 2% and a WACC of 9.46%, the company's fair equity value is estimated at RMB 16.3 billion, equivalent to HKD 17.6 billion (exchange rate: RMB 1 = HKD 1.08) [3] - The company's gross margin is expected to remain stable, ranging from 89.44% to 91.00% from 2024 to 2026 [4] - Net profit attributable to shareholders is forecasted to be negative, with losses of RMB 704 million, RMB 772 million, and RMB 512 million for 2024, 2025, and 2026, respectively [4] - ROE is expected to remain negative, ranging from -30.7% to -50.4% over the same period [4]