Investment Rating - The report assigns a "Buy" rating for Kelun Biotech, marking its first coverage with a target price of 300 HKD [1]. Core Insights - Kelun Biotech is transitioning towards an integrated model of research and sales, with its core product, SKB264 (Lukangshatuo monoclonal antibody), having received approval for two indications in China [6][18]. - The company has a robust pipeline with over 30 products in development, including 11 ADC (Antibody-Drug Conjugate) candidates that are in clinical stages [11][18]. - The partnership with MSD has led to 12 global Phase III studies for SKB264, enhancing its clinical and commercial potential [7][32]. Summary by Sections Major Data - The company operates in the pharmaceutical industry, with a total market capitalization of 63.32 billion CNY and a debt-to-asset ratio of 22.48% [1]. Financial Performance - In 2024, the company reported a revenue of 1.933 billion CNY, a year-on-year increase of 25.5%, while net losses narrowed to 267 million CNY, a 53.5% improvement from the previous year [6][16]. - The gross margin is projected to improve from 49.3% in 2023 to 80.2% by 2027, indicating a positive trend in profitability [5]. Product Pipeline - The core product SKB264 has been approved for treating 3L TNBC and 3L EGFR mutation NSCLC, with additional applications pending for 2L EGFR mutation NSCLC expected to be approved in 2025 [30][29]. - The company has established a strong ADC platform and is actively pursuing global collaborations to maximize the potential of its pipeline [11][18]. Strategic Positioning - Kelun Biotech aims to become a comprehensive pharmaceutical company through innovation, global partnerships, and self-sales capabilities, with a focus on expanding its commercial team and enhancing market access [18][6]. - The management team comprises experienced professionals from both domestic and international pharmaceutical sectors, which is expected to drive the company's long-term growth [14].
科伦博泰生物-B（06990）：科伦博泰生物-b（06990）：朝向研发销售一体化转型，芦康沙妥珠单抗国内已获批两项适应症