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泽璟制药(688266):吉卡昔替尼将参与医保谈判,多抗组合覆盖优势领域

Investment Rating - The report maintains a "Buy" rating for the company, indicating a positive outlook for future investment returns [10]. Core Insights - The company reported a revenue of 376 million yuan for the first half of 2025, representing a year-on-year increase of 56.07%. However, the net profit attributable to the parent company was a loss of 73 million yuan, a decrease of 9.42% year-on-year [5]. - The company is advancing its commercialization process, with the drug Jika Xiqi (盐酸吉卡昔替尼) preparing for negotiations to be included in the national medical insurance directory [7]. - The company has made significant progress in its innovative pipeline, with multiple bispecific antibodies entering clinical trials and showing promising results [8]. Financial Performance - The overall gross margin for the first half of the year was 89.67%, a decrease of 3.07 percentage points year-on-year. The operating cash flow was negative 17 million yuan, a decline of 115.12% year-on-year [6]. - The company expects revenues of 900 million yuan, 1.65 billion yuan, and 2.41 billion yuan for 2025, 2026, and 2027, respectively, with corresponding year-on-year growth rates of 68.7%, 83.2%, and 46.2% [10]. - The projected net profit attributable to the parent company for the same years is 73 million yuan, 530 million yuan, and 1.02 billion yuan, with year-on-year growth rates of 152.7%, 628.6%, and 93.1% [10]. Product Development - The company’s drug ZGGS15 (LAG3/TIGIT) has received IND approval in both China and the US, marking it as the first of its kind to enter clinical research [8]. - The drug Zepu Ping (盐酸吉卡昔替尼片) was approved for market entry in May 2025 and is set to participate in the national medical insurance negotiations [9]. - The company has established a commercial presence in over 1,200 hospitals and 2,200 pharmacies for its product Zepu Sheng (甲磺酸多纳非尼片) [9].