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康缘药业(600557):创新药研发加速,多个产品有望取得关键临床进展

Investment Rating - The investment rating for the company is "Buy-A" with a 6-month target price of 24.42 CNY [5][7]. Core Views - The company's short-term performance is under pressure due to a high base from the previous year and external factors affecting the traditional Chinese medicine sector, but these impacts are expected to weaken over time. The company has a rich pipeline of innovative drugs, including the next-generation acetylcholinesterase inhibitor, Fluoroprazole, and dual-target weight loss drugs ZX2010 and ZX2021, which are anticipated to yield significant clinical data in the near future [1][2][3]. Financial Performance - In the first half of 2025, the company achieved revenue of 1.642 billion CNY, a year-on-year decline of 27.36%, and a net profit attributable to shareholders of 142 million CNY, down 46.36%. The decline in core business is primarily due to the high base effect from the previous year, compounded by macroeconomic conditions and policy impacts on the pharmaceutical industry [2][3]. Innovation and Drug Development - The company is accelerating its progress in both biological and chemical innovative drug sectors, with multiple catalysts expected in the future. Key developments include: - Chemical drugs: Fluoroprazole has completed Phase II clinical data collection, while other drugs are actively advancing through Phase II trials [3]. - Biological drugs: The triple-target weight loss drug ZX2021 and dual-target weight loss drug ZX2010 are in Phase II clinical stages, with significant progress anticipated by Q4 2025 [3]. Financial Projections - The company is projected to have revenue growth rates of 1.8%, 8.7%, and 9.4% for 2025, 2026, and 2027, respectively. Net profit growth rates are expected to be 0.8%, 11.3%, and 12.3% for the same years [7][8].