医药生物行业周报:药品目录协商结束,商保创新药目录可期-20251107

Investment Rating - The industry investment rating is "Positive" and the specific company rating for 恒瑞医药 (Hengrui Medicine) is "Buy" [2][55]. Core Insights - The 2025 drug directory negotiations have concluded successfully, with the new basic medical insurance drug directory and the first commercial insurance innovative drug directory expected to be released in December [10]. - Novo Nordisk and Eli Lilly have reached an agreement with the U.S. government to significantly reduce the prices of GLP-1 drugs starting in 2026, enhancing drug accessibility for patients [11]. - Blackstone has invested $700 million in the development of sac-TMT, a significant ADC drug [12]. - Fosun Pharma's MEK inhibitor, Luwomei, is set for priority review for a new indication [13]. Industry News - The negotiations for the 2025 drug directory have been successfully completed, with 120 companies participating [10]. - The new drug pricing agreements aim to improve patient affordability and access, with specific price reductions outlined for various drugs [11]. - The market performance of the pharmaceutical sector shows a slight increase, with the pharmaceutical index rising by 0.32% during the week [46]. Company Announcements - 百济神州 (BeiGene) reported a revenue of 27.595 billion yuan for the first three quarters of 2025, a year-on-year increase of 44.2% [29]. - 晶泰控股 (Jintai Holdings) announced a strategic partnership with Eli Lilly to enhance the development of AI-driven bispecific antibodies [30]. - 恒瑞医药 (Hengrui Medicine) has a drug under review for priority approval for treating patients with paroxysmal nocturnal hemoglobinuria [31]. - 百利天恒 (Baili Tianheng) has its HER2 ADC drug included in the list of breakthrough therapy products [32]. Market Review - The SW pharmaceutical industry’s price-to-earnings ratio (TTM) is 29.97, with a valuation premium of 133% compared to the CSI 300 index [50]. - The overall market performance for the week shows mixed results, with most sub-sectors experiencing gains, particularly traditional Chinese medicine [46]. Weekly Strategy - The report suggests focusing on pharmaceutical companies related to the drug directory negotiations and those showing improved fundamentals and performance reversals, particularly in the CXO and medical device sectors [55].