维立志博-B(09887):研发日跟踪点评:崭露头角,蓄势待发

Investment Rating - The investment rating for the company is "Buy" [1] Core Insights - The report highlights the promising advancements in the company's product pipeline, particularly LBL-034 and LBL-024, which are positioned to redefine treatment paradigms in multiple myeloma and other cancers [3][4] - The company has a strong financial position with sufficient cash reserves to support multiple research pipelines, bolstered by recent fundraising efforts [6] - Revenue projections indicate a gradual increase, with expected revenues of 260 million in 2025, 284 million in 2026, and 467 million in 2027, reflecting a growth rate of 64% in 2027 [5][6] Summary by Sections Product Development - LBL-034 has shown a 90.9% overall response rate (ORR) in a specific dosage group for treating relapsed/refractory multiple myeloma, demonstrating "Best-in-class" potential compared to competitors [3] - LBL-024 has effectively addressed liver toxicity issues associated with 4-1BB agonists, with a reported ≥3 grade liver enzyme elevation of only 1.3% across approximately 450 enrolled patients [4] - Initial clinical data for LBL-024 in non-small cell lung cancer (NSCLC) shows an ORR of 50% and a disease control rate (DCR) of 94.4%, indicating significant therapeutic potential [4] Financial Projections - The company is projected to have total revenues of 260 million, 284 million, and 467 million from 2025 to 2027, with year-over-year growth rates of 9% and 64% respectively [5] - The net profit attributable to the parent company is expected to be -416 million, -518 million, and -719 million for the same period, with a declining growth rate [5][6] - The gross margin is anticipated to be 100% in 2025 and 2026, decreasing to 93.68% in 2027 [5] Cash Position - As of the first half of 2025, the company had cash and cash equivalents of 422 million, supplemented by net proceeds of 1.363 billion HKD from its initial public offering [6]