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博瑞医药半年报:二季度环比改善,研发强度升至65%,加码GLP-1矩阵

Core Viewpoint - The article discusses the financial performance and strategic direction of Borui Pharmaceutical, highlighting its revenue fluctuations, R&D investments, and innovative drug development efforts, particularly in the GLP-1 and GIP receptor agonist space. Financial Performance - In the first half of 2025, Borui Pharmaceutical reported total revenue of 537 million RMB, a year-on-year decline of 18.28%, and a net profit of 17.17 million RMB, down 83.85% year-on-year [8][16]. - The revenue decline is attributed to high base effects from previous flu outbreaks affecting the demand for antiviral raw materials and formulations [8][11]. - The company experienced a 16% quarter-on-quarter growth in Q2, with antiviral raw material revenue dropping over 60% compared to the previous year [8][13]. R&D Investment - Borui Pharmaceutical's R&D expenditure reached 348 million RMB in the first half of 2025, a 144.07% increase year-on-year, representing approximately 65% of total revenue [17][20]. - The company is focusing its R&D efforts on innovative drugs, with over 90% of the investment directed towards new drug development and inhalation formulations [20][22]. Innovative Drug Development - The company is advancing its proprietary GLP-1 and GIP receptor dual agonist, BGM0504, which is currently in Phase III clinical trials for type 2 diabetes and weight management [22][23]. - BGM0504 has shown promising results in clinical trials, demonstrating better glycemic control compared to Semaglutide and significant weight management potential [22][26]. - Borui Pharmaceutical is also developing additional innovative drugs, including BGM1812 and BGM2102, which are in preclinical stages and aim to enhance metabolic regulation and treatment efficacy [24][27][31]. Market Potential - The global market for GLP-1 drugs is projected to grow from 51.8 billion USD in 2024 to 88.1 billion USD by 2030, indicating significant commercial opportunities for Borui Pharmaceutical's innovative products [31][33]. - The company is strategically positioned to capitalize on this market growth through its diverse product pipeline and strong R&D focus [32][33].