速递|派格生物:解散旗下GLP-2研发子公司,专注PB-119

Core Insights - The article discusses the strategic decision by the company to voluntarily dissolve its non-wholly owned subsidiary, Shanghai Maiji Biopharmaceutical Technology Co., Ltd., to focus on core product lines amid increasing competition and resource constraints [5] - The company is advancing its key product PB-119, a long-acting GLP-1 receptor agonist, which has received acceptance for its new drug application for the treatment of type 2 diabetes by the National Medical Products Administration in September 2023 [7] - The company has also signed a collaboration agreement with PDC FZ-LLC for the exclusive development and commercialization of PB-119 in the Middle East and Africa [9] Company Strategy - The dissolution of Shanghai Maiji is seen as a proactive adjustment to concentrate resources on core projects, particularly in the metabolic and weight loss treatment sectors [5] - The company aims to enhance its product matrix centered around PB-119, which is positioned as a first-line treatment for type 2 diabetes and obesity [7] Product Development - PB-119 is designed to be administered once weekly, simplifying the clinical administration process and potentially improving patient compliance [7] - The company is also developing PB-718, a long-acting GLP-1/GCG dual receptor agonist targeting obesity and NASH, with plans for clinical trials in China [9][10]