消息面上，派格生物医药近日公布，宣布与阿联酋领先医药研发机构PDC FZ-LLC达成战略合作，独家 授予其在中东及非洲地区开发、分销、营销及商业化派格生物的核心产品Visepegenatide (PB-119)。此 次合作标志着派格生物全球商业化战略迈出关键一步。 据悉，Visepegenatide (PB-119) 是派格生物自主研发的一款每周一次皮下注射的GLP-1受体激动剂，用 于治疗2型糖尿病和体重管理。据国际糖尿病联盟数据显示，中东及北非地区成年糖尿病患病率高达 16.2%，位居全球首位。此次合作有望加速Visepegenatide (PB-119)这一创新疗法惠及该地区众多未满足 医疗需求的患者。 智通财经APP获悉，派格生物医药-B(02565)尾盘涨超20%，高见62.25港元，再创上市新高。截至发 稿，涨16.51%，报60.3港元，成交额3023.46万港元。 ...

据悉，Visepegenatide(PB-119)是派格生物自主研发的一款每周一次皮下注射的GLP-1受体激动剂，用于 治疗2型糖尿病和体重管理。据国际糖尿病联盟数据显示，中东及北非地区成年糖尿病患病率高达 16.2%，位居全球首位。此次合作有望加速Visepegenatide(PB-119)这一创新疗法惠及该地区众多未满足 医疗需求的患者。 派格生物医药-B(02565)尾盘涨超20%，高见62.25港元，再创上市新高。截至发稿，涨16.51%，报60.3 港元，成交额3023.46万港元。 消息面上，派格生物医药近日公布，宣布与阿联酋领先医药研发机构PDC FZ-LLC达成战略合作，独家 授予其在中东及非洲地区开发、分销、营销及商业化派格生物的核心产品Visepegenatide(PB-119)。此次 合作标志着派格生物全球商业化战略迈出关键一步。 ...

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Core Insights - The collaboration between Paige Biopharma and PDC grants exclusive rights for the development, distribution, marketing, and commercialization of Visepegenatide (PB-119) in the Middle East and Africa [1] Market Opportunity - The Middle East and North Africa (MENA) region has a high diabetes prevalence rate of 16.2%, the highest globally, driven by dietary and lifestyle factors [2] - The pharmaceutical market for digestive and metabolic drugs, including diabetes treatments, holds a 20.4% market share in the region, with a significant growth of 22.1% in Q1 2025 [2] - The number of diabetes patients in Africa is projected to increase by nearly 142% by 2050, indicating substantial market potential for diabetes and obesity treatment drugs [2] - The global weight management drug market is expected to grow from $99.7 billion in 2020 to $112.8 billion by 2024, with a compound annual growth rate (CAGR) of 3.1%, potentially reaching $277.4 billion by 2034 [2] - The demand for weight management drugs in the MENA region is anticipated to be the highest globally, potentially reaching a scale of $10 billion by 2034 [2] Product Overview - Visepegenatide (PB-119) is a once-weekly subcutaneous GLP-1 receptor agonist developed by Paige Biopharma for the treatment of type 2 diabetes and weight management [3] - The product demonstrates superior clinical characteristics compared to some existing products, including good safety, tolerability, and significant effects on blood sugar reduction and weight loss [3] - The innovative molecular design and long-acting mechanism of Visepegenatide (PB-119) provide patients with a more convenient and stable treatment option, representing the future direction of GLP-1 therapies [3] - The partnership with PDC is expected to leverage local advantages to expedite the development, registration, and commercialization of Visepegenatide (PB-119) in the MENA region, creating long-term value for the company and hope for patients with metabolic diseases globally [3]

Core Insights - The collaboration between Paige Biopharma and PDC grants exclusive rights for the development, distribution, marketing, and commercialization of Visepegenatide (PB-119) in the Middle East and Africa [1] Market Opportunity - The Middle East and North Africa (MENA) region has a high diabetes prevalence rate of 16.2%, the highest globally, driven by dietary and lifestyle factors [2] - The therapeutic area of digestive and metabolic drugs, including diabetes treatments, holds a 20.4% market share in the MENA pharmaceutical market, with a significant growth of 22.1% in Q1 2025 [2] - The number of diabetes patients in Africa is projected to increase by nearly 142% by 2050, indicating substantial market potential for diabetes and obesity treatment drugs [2] - The global weight management drug market is expected to grow from $99.7 billion in 2020 to $112.8 billion in 2024, with a compound annual growth rate (CAGR) of 3.1%, potentially reaching $277.4 billion by 2034 [2] - The demand for weight management drugs in the MENA region is anticipated to be the highest globally, reaching a scale of $10 billion by 2034 [2] Product Overview - Visepegenatide (PB-119) is a once-weekly subcutaneous GLP-1 receptor agonist developed by Paige Biopharma for the treatment of type 2 diabetes and weight management [3] - The product demonstrates superior clinical characteristics compared to some existing products, including good safety, tolerability, and significant effects on blood sugar reduction and weight loss [3] - The innovative molecular design and long-acting mechanism of Visepegenatide (PB-119) provide patients with a more convenient and stable treatment option, representing the future direction of GLP-1 therapies [3] - The partnership with PDC is expected to leverage local advantages to expedite the development, registration, and commercialization of Visepegenatide (PB-119) in the MENA region, creating long-term value for the company and hope for patients with metabolic diseases globally [3]

Core Viewpoint - The company has entered into a non-binding term sheet with PDC in the UAE for the exclusive licensing of its product Visepegenatide (PB-119), a GLP-1 receptor agonist for type 2 diabetes and weight management, marking a significant milestone in its global commercialization strategy [1][2] Group 1 - The agreement grants PDC exclusive rights to develop, distribute, market, and commercialize PB-119 in the Middle East and Africa, including local production and comprehensive technology transfer [1] - The partnership is strategically important as PDC's extensive regional expertise and infrastructure can accelerate market access and penetration, validating the company's asset output strategy [1][2] - The Middle East and Africa represent a large and growing market for diabetes and obesity treatment, highlighting the unmet medical needs and commercial potential for innovative therapies like PB-119 [1] Group 2 - PDC is a leading pharmaceutical R&D institution in the region with a strong track record in clinical trials, providing end-to-end innovative solutions for clinical studies and life sciences [2] - The collaboration with PDC reinforces the company's proprietary R&D capabilities and the clinical characteristics of Visepegenatide (PB-119), showcasing its significant market potential [2] - This partnership is a crucial step in expanding the global footprint of PB-119 and aligns with the overall interests of the company and its shareholders [2]

Core Viewpoint - The company has entered into a non-binding term sheet with PDC FZ-LLC for the exclusive licensing of its product Visepegenatide (PB-119), a GLP-1 receptor agonist for treating type 2 diabetes and weight management, in the Middle East and Africa [1][2] Group 1: Licensing Agreement - The agreement grants PDC exclusive rights to develop, distribute, market, and commercialize PB-119 in the Middle East and Africa [1] - This partnership is a significant milestone in the global commercialization strategy for PB-119, covering regional development, product registration, local production with full technology transfer, and exclusive commercialization rights [1] Group 2: Strategic Importance - The collaboration is strategically important as PDC's extensive regional expertise and infrastructure can accelerate market access and penetration [1] - The partnership validates the company's asset output strategy and contributes significantly to the global positioning of PB-119 and the long-term value creation for the company [1] Group 3: Market Potential - The Middle East and Africa represent a large and continuously growing market for diabetes and obesity treatment drugs, highlighting the unmet medical needs and commercial potential for innovative therapies like PB-119 [1][2] - The high prevalence and rising trend of these diseases underscore the significant market opportunity for PB-119 in these regions [1]

Core Viewpoint - The company has entered into a non-binding term sheet with PDC FZ-LLC for the exclusive licensing of its product Visepegenatide (PB-119), a GLP-1 receptor agonist for the treatment of type 2 diabetes and weight management, in the Middle East and Africa [1][2] Group 1: Licensing Agreement - The agreement grants PDC exclusive rights to develop, distribute, market, and commercialize PB-119 in the Middle East and Africa [1] - The licensing includes regional development, product registration, local production involving comprehensive technology transfer, and exclusive commercialization rights [1] - The product will be marketed under a trademark owned by PDC in the specified regions [1] Group 2: Strategic Importance - This partnership is a significant milestone in the global commercialization strategy for PB-119, leveraging PDC's extensive regional expertise and infrastructure to accelerate market access and penetration [1][2] - The collaboration validates the company's asset output strategy and contributes significantly to the global positioning of the product and the long-term value creation for the company [1] Group 3: Market Potential - The Middle East and Africa represent a large and continuously growing market for diabetes and obesity treatment drugs, highlighting the unmet medical needs and commercial potential for innovative therapies like PB-119 [1] - The high prevalence and rising trends of these diseases underscore the importance of PB-119 in addressing significant healthcare demands in the region [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容而產生或因倚賴 該等內容而引致的任何損失承擔任何責任。 PegBio Co., Ltd. 派格生物醫藥（杭州）股份有限公司 （於中華人民共和國註冊成立的股份有限公司） 根據建議條款，PDC將獲授獨家許可，以於中東及非洲地區（「該地區」）開發、分 銷、營銷及商業化該產品。是次合作為本公司PB-119全球商業化戰略的重要里程 碑。該許可涵蓋區域開發、產品註冊、涉及全面技術轉讓的本地生產，以及全面 商業化的獨家權利。該產品將以PDC擁有的商標於該地區內銷售。 該合作夥伴關係具有重要的戰略意義，憑藉PDC廣泛的區域專業經驗及基礎設 施，可加速市場准入及滲透，印證本公司的資產輸出戰略，並為該產品的全球佈 局及本公司的長期價值創造作出重大貢獻。 中東及非洲地區為糖尿病及肥胖症治療藥物提供龐大且持續增長的市場。該等疾 病的高發病率及不斷上升的趨勢凸顯PB-119等創新療法存在巨大的未滿足醫療需 求及商業潛力。 1 PDC為中東及非洲地區首屈一指的製藥研發機構，於進行臨床試驗 ...

FF301 股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年9月30日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 派格生物醫藥 ( 杭州 ) 股份有限公司 呈交日期: 2025年10月6日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02565 | 說明 | H股 | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 279,164,339 | RMB | | 1 RMB | | 279,164,339 | | 增加 / 減少 (-) | | | 0 | | | RMB | | 0 | | 本月底結存 | | | 279,164,339 | RMB | | 1 RMB | | 279,164,339 | | 2. 股份分類 | 普通 ...