智通财经APP获悉，艾伯维(ABBV.US)的收购标的Cerevel Therapeutics(CERE.US)周四宣布，其每日一次的帕金森病口服候选药物tavapadon在一项作为联合疗法的关键性三期试验中达成主要目标。 该公司说，针对帕金森病晚期成人患者的TEMPO-3研究表明，在主要终点方面，他伐帕东与脑部疗法左旋多巴联合用药与安慰剂加左旋多巴相比，具有临床意义和显著的统计学差异。 这项为期27周、针对507名患者的研究将无运动障碍总“开启”时间与基线假设相比的变化作为主要终点，结果显示，与安慰剂对照组(1.7小时对0.6小时)相比，服药组的“开启”时间增加了1.1小时。 此外，与安慰剂对照组相比，他伐帕东加左旋多巴组的关键次要终点“关闭”时间也具有有统计学意义的显著缩短。 关于安全性，该公司补充说，研究药物的耐受性良好，大多数不良反应程度为轻度至中度。 Cerevel希望利用这些研究结果支持未来的他伐帕东监管申请。该候选药物在帕金森病中的两项后期单一疗法试验的顶线数据预计将于2024年下半年公布。 去年12月，艾伯维同意以87亿美元收购Cerevel。由于Cerevel是一家领先的精神分裂症药物开发商 ...

−     Results from the Phase 3 SELECT-GCA study showed 46 percent of patients with giant cell arteritis (GCA) who were treated with upadacitinib (RINVOQ®; 15 mg) with a 26-week steroid taper regimen achieved sustained remission from week 12 through week 52 compared to 29 percent of patients receiving placebo with a 52-week steroid taper regimen1−     The safety profile in GCA was generally consistent with that in approved indications, and no new safety signals were identified1 −     The clinical program ref ...

The latest trading session saw AbbVie (ABBV) ending at $164.25, denoting a +1.05% adjustment from its last day's close. The stock's performance was ahead of the S&P 500's daily loss of 0.58%. On the other hand, the Dow registered a loss of 0.12%, and the technology-centric Nasdaq decreased by 1.15%.Prior to today's trading, shares of the drugmaker had lost 9.53% over the past month. This has lagged the Medical sector's loss of 6.07% and the S&P 500's loss of 1.09% in that time.Market participants will be cl ...

Blue-chip dividend stocks have always been relevant. While they’re not the most exciting investments, they provide a steady hand during market uncertainty. This attribute has just become even more critical.With an already tense situation in the geopolitical realm boiling over, investors will likely seek reassurances. It doesn’t get much better than established stalwarts that pay consistent and/or reliable passive income. On this note, below are top blue-chip dividend stocks to consider.RTX (RTX)Source: JHVE ...

Everything is going according to plan, and more growth is on the way.Big pharma stocks like AbbVie (ABBV -2.22%) usually aren't high on the list that investors look to for opportunities that could make them into millionaires. After all, they aren't typically in the news for good reasons, and despite relying on the lifesaving medicines that they produce, most people aren't talking to their coworkers about how their products are going to be in every household or core enablers for some grand global trend.But a ...

vzphotos Investment thesis AbbVie (NYSE:ABBV) is a profitability superstar, generating almost 40% in free cash flow margin even when I deduct stock-based compensation. The company has a stellar revenue growth trajectory over the past decade, which was fueled mostly by strategic acquisitions. The approach is aggressive, but AbbVie's strong track record of success increases my confidence in future growth. AbbVie has a diverse portfolio of products across several promising drug markets. The valuation looks ...

PM Images Shareholders of AbbVie Inc. (NYSE:ABBV) should be thrilled with its overall results, as just the appreciation over the past decade has outperformed the market. Shares of ABBV have appreciated by 248.90% over the past decade and by 104.87% over the past 5 years. The SPDR S&P 500 ETF Trust (SPY), which is what I use to track the market, has appreciated by 78.52% over the past 5 years, and by 175.83% over the past decade. ABBV is one of those companies that continues to outpace the market, and when t ...

-     Interim analysis of an ongoing 156-week extension study supports long-term safety, tolerability and efficacy of atogepant 60 mg to prevent chronic and episodic migraine-     Seventy percent of subjects achieved ≥50% reduction in monthly migraine days at Weeks 13-16 and this was consistent during the 48 weeks of open-label treatment-     Findings will be showcased in an oral presentation at the American Academy of Neurology (AAN) Annual Meeting Scientific Platform Session for Emerging Science NORTH CHI ...

AbbVie (ABBV) closed the latest trading day at $167.52, indicating a -0.89% change from the previous session's end. This change lagged the S&P 500's daily gain of 0.74%. Meanwhile, the Dow experienced a drop of 0.01%, and the technology-dominated Nasdaq saw an increase of 1.68%.The drugmaker's stock has dropped by 6.02% in the past month, falling short of the Medical sector's loss of 4.72% and the S&P 500's gain of 0.8%.Investors will be eagerly watching for the performance of AbbVie in its upcoming earning ...

Biotech stocks were among the worst performers in 2023. And so far in 2024, investors are still waiting on the recovery rally. Many small-cap biotech stocks are being held back by the Fed’s more restrictive stance on interest rates. But even some of the large-cap names with commercially available drugs that are household names are also underperforming the market. But “some” isn’t the same as “all.” In a stock picker’s market, you want to find the stocks that have a chance to outperform. One way to find thes ...