CANADA - 2025/04/03: In this photo illustration, the AbbVie logo is seen displayed on a smartphone ... More screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)SOPA Images/LightRocket via Getty ImagesAbbVie (NASDAQ:ABBV) has distinguished itself as one of the top performers in the healthcare sector this year, with its stock rising by 6% while the broader S&P 500 healthcare index fell by 1%. This outperformance is indicative of investor confidence in the pharmaceutical giant ...

Key Takeaways ABBV is expanding its pipeline with over 20 early-stage deals across immunology, oncology and neuroscience. The $2.1 billion Capstan deal adds a first-in-class CAR-T therapy and proprietary RNA delivery platform. Acquisitions of ImmunoGen and Cerevel have diversified ABBV's portfolio across multiple therapeutic areas.AbbVie (ABBV) has been actively ramping up its deal-making efforts lately, thereby strengthening its pipeline. While immunology remains its core area, the company is also signin ...

21世纪经济报道记者韩利明上海报道 当地时间6月30日，全球制药巨头艾伯维（纽约证券交易所代码：ABBV）宣布，将以高达21亿美元的 现金收购生物技术新锐公司Capstan Therapeutics，Inc.（下称"Capstan"）。 此次收购，艾伯维不仅囊获一项处于1期临床、用于治疗B细胞介导自身免疫性疾病的潜在同类首创 tLNP抗CD19 CAR-T疗法候选药物CPTX2309，还将获得Capstan专有的tLNP（脂质纳米颗粒）平台技 术，该技术可实现RNA有效载荷（如mRNA）的递送，从而在体内设计特定细胞类型。 成立于2022年9月的Capstan Therapeutics，聚焦开发LNP-mRNA路线的体内CAR-T疗法，曾在A轮融资中 斩获近1亿美元，由辉瑞风险投资公司领投，众多知名药企及投资机构纷纷参与。其总裁兼首席执行官 Laura Shawver博士期望凭借艾伯维在免疫学研究、临床开发方面的世界领先专业知识及其商业化能 力，将创新疗法带给更多患者。 "Capstan在体内CAR-T赛道处于领先地位，今年6月，Capstan及宾夕法尼亚大学的研究人员在 《Science》期刊发表的一项研究 ...

Key Takeaways AbbVie is acquiring Capstan Therapeutics for up to $2.1B to expand its immunology portfolio. The acquisition adds CPTX2309, a phase I in vivo CAR-T therapy for autoimmune diseases, to AbbVie's pipeline. Capstan's CellSeeker tLNP platform enables RNA delivery to engineer specific cell types inside the body.AbbVie (ABBV) announced that it has entered into a definitive agreement to acquire privately held biotech, Capstan Therapeutics, for up to $2.1 billion in cash.The impending acquisition wil ...

日前， 艾伯维 （AbbVie） 宣布 全力进军 in vivo CAR-T 市场，将斥资 21 亿美元现金 收购 Capstan Therapeutics ，以期将一款处于 1 期临床实验阶段的自 身免疫疾病候选 invivo CAR-T 细胞疗法 （ CPTX2309 ） 纳入其研发管线。 撰文丨王聪 编辑丨王多鱼 排版丨水成文 创立于 2022 年的 Capstan 公司，致力于通过在体内 （ in vivo ） 而非体外重新编程 T 细胞，从而清除阻碍 CAR-T 细胞疗法普及面临的制造和可扩展性方面 的挑战，且患者在治疗前无需接受淋巴细胞清除化疗。 Capstan 公司创立始于 2022 年初的一篇论文。 体内生成 CAR-T 细胞，治疗心脏损伤 2022 年 1 月 6 日，宾夕法尼亚大学的研究人员在 Science 期刊发表了题为： CAR T cells produced in vivo to treat cardiac injury 研究论文 【1】 ，开发了一 种 在体内原位生成 CAR-T 细胞的新技术 （ in vivo CAR-T） ，通过 注射脂质纳米颗粒 （LNP） 递送 mRN ...

该方法类似于mRNA疫苗，仅需简单注射，就能在体内生成CAR-T细胞疗法，无需实验室细胞制造和体 外扩增，有望解决当前CAR-T细胞疗法工艺复杂、周期长、价格高昂等关键难题。 当地时间6月30日，制药公司艾伯维宣布，将以21亿美元的价格收购体内CAR-T细胞疗法开发商Capstan Therapeutics，以扩大自身免疫性疾病疗法的产品线。 自2023年艾伯维的明星药物阿达木单抗（修美乐）专利到期以来，艾伯维已斥资超过200亿美元进行大 手笔收购。该公司正在与Vertex、百时美施贵宝（BMS）等制药巨头在自身免疫药物领域展开竞争。 艾伯维最新押注的Capstan基于mRNA技术开发CAR-T疗法。通过此项交易，艾伯维将获得Capstan公司 包括脂质纳米颗粒（tLNP）在内的核心平台技术。该技术可通过重新编程细胞治疗疾病，在自身免疫 性疾病领域具有广阔的潜力。 有市场研究数据显示，CAR-T疗法市场规模今年将突破110亿美元，到2034年有望飙升至接近2000亿美 元的规模。 Capstan公司成立于2022年，由美国宾夕法尼亚大学医学院顶尖团队领衔。该公司科学团队创始人阵容 豪华，包括CAR-T先驱卡尔 ...

Capstan's lead asset, CPTX2309, is a targeted lipid nanoparticle (tLNP) that delivers an mRNA encoding an anti-CD19 chimeric antigen receptor (CAR) to CD8-expressing cytotoxic T cells in vivo, and is a potential first-in-class product for treating B cell-mediated autoimmune diseases Proposed acquisition strengthens AbbVie's commitment to transforming the future of patient care with Capstan's innovative tLNP platform technologyNORTH CHICAGO, Ill. and SAN DIEGO, June 30, 2025 /PRNewswire/ -- AbbVie (NYSE: AB ...

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Performance Comparison - The Dividend Aristocrats experienced an average gain of 0.36% in June, significantly underperforming compared to the SPDR S&P 500 Trust ETF (SPY), which had a gain of 4.64% [1] Analyst Insights - The article is authored by an analyst with over 10 years of experience in the investment arena, indicating a strong background in financial analysis and investment strategies [1] Investment Focus - The analyst expresses a personal interest in dividend investing, suggesting a focus on companies that consistently increase their dividends, which may appeal to income-focused investors [1]

Core Viewpoint - The healthcare sector is positioned as a strong long-term investment opportunity, with a focus on companies that have shown adaptability and are well-prepared for future challenges [2]. Group 1: Abbott Laboratories - Abbott Laboratories, founded in 1888, has a market capitalization of $240 billion and offers diverse healthcare products across multiple sectors [4]. - The company is a leader in medical devices, diagnostics, nutritional products, and established pharmaceuticals, with notable products like the MitraClip and FreeStyle Libre [5][6]. - Abbott anticipates an 8% year-over-year revenue growth in 2025 and continues to innovate, recently receiving the European CE Mark for the Volt PFA System [7][8]. - Abbott has a strong dividend history, having increased its dividend for 53 consecutive years [8]. Group 2: AbbVie - AbbVie, spun off from Abbott in 2013, has a market capitalization of approximately $328 billion and generated $56.3 billion in sales last year [9][10]. - The company has successfully navigated the loss of U.S. exclusivity for its top product, Humira, by investing in R&D and acquisitions, leading to a robust product pipeline [11]. - AbbVie’s successors to Humira, Rinvoq and Skyrizi, are projected to generate combined sales of $31 billion by 2027, surpassing Humira's peak sales [12]. - AbbVie has increased its dividend by a cumulative 310% since its spin-off, with a forward dividend yield of 3.51% [12]. - The stock is considered relatively inexpensive, trading at 15.2 times forward earnings, with growth potential from new products [13].