Accessibility StatementSkip Navigation SAN DIEGO, Nov. 25, 2025 /PRNewswire/ -- Halozyme Therapeutics, Inc. (NASDAQ: HALO) ("Halozyme") today announced that Dr. Helen Torley, president and chief executive officer, will present and host investor meetings at the 8th Annual Evercore Healthcare Conference. The presentation is scheduled for Tuesday, December 2 at 10:20am PT / 1:20pm ET. A live audio webcast will be available on the Investor Relations section of the Company's website. Replays of the audio webc ...

Core Insights - Aptar Group has been in operation for approximately 80 years and has been publicly traded for 35 years, with the pharmaceutical segment contributing nearly 70% of EBITDA [2]. Company Overview - The company focuses on proprietary drug delivery devices, primarily for nasal and inhalation applications, as well as ophthalmic and dermal delivery systems [2]. - The beauty and closure segments also contribute to the company's portfolio, targeting demographics such as the aging population and health-conscious consumers [3]. Market Focus - Aptar Group's pharmaceutical applications are mainly aimed at chronic disease treatments, including asthma, COPD, and allergic rhinitis, which require daily medication [3]. - The company organizes its operations into three reporting segments but manages its business primarily through technology platforms [3].

Core Insights - Lexaria Bioscience Corp. has extended its Material Transfer Agreement (MTA) with PharmaCO until April 30, 2026, to allow for the review of data from an Australian study [2][3] - The MTA enables continued collaboration and strategic planning discussions between Lexaria and PharmaCO's clinical development team [2] - Lexaria's DehydraTECH™ technology aims to enhance drug delivery through oral administration, improving bio-absorption and reducing side effects [4] Summary by Sections Material Transfer Agreement Update - The MTA originally signed on September 4, 2024, has been extended to accommodate PharmaCO's review of Lexaria's Australian study data [2] - This extension allows both parties to maintain their relationship and keep the temporary exclusive license active [2] Pre-Clinical Studies and Future Expectations - Initial pre-clinical studies examining pharmacokinetics in animals have been completed [3] - Lexaria is awaiting PharmaCO's review of safety, pharmacokinetic, and efficacy data from its independent Australian human clinical study, with final results expected by the end of Q4 2025 [3] About Lexaria and DehydraTECH - DehydraTECH™ is a patented drug delivery platform that enhances the absorption of various drugs through oral delivery [4] - Lexaria holds a strong intellectual property portfolio with 54 patents granted and additional patents pending globally [4]

Core Insights - Aspire Biopharma successfully participated in the CPHI Frankfurt trade show, engaging in strategic discussions with global pharmaceutical companies regarding its sublingual high-dose aspirin product [1][2][3] Company Update - Aspire Biopharma Holdings, Inc. is focused on advancing partnership discussions for its novel sublingual high-dose aspirin, which utilizes a patent-pending drug delivery technology [1][5] - The company conducted 16 formal meetings and numerous informal conversations with representatives from major industry players, including Deva Holdings, Bayer, and Key Pharmaceuticals [2][3] - The management team highlighted the positive reception of their clinical data during discussions, emphasizing the product's potential for treating acute myocardial infarction (AMI) [3][4] Industry Context - CPHI Frankfurt is the world's largest pharmaceutical event, hosting over 63,000 attendees and 2,400 exhibitors, providing a platform for collaboration and business development within the pharma supply chain [2] - The event allowed Aspire to showcase its innovative delivery solutions and explore joint venture and licensing opportunities with leading pharmaceutical companies [4]

Financial Performance - Royalty revenue increased 52% year-over-year to a record $236 million, driving total revenue to a record $354 million, representing a 22% increase year-over-year [1][3][13] - Net income rose 28% year-over-year to $175 million, with adjusted EBITDA increasing 35% year-over-year to $248 million [1][10][13] - GAAP diluted EPS increased 36% year-over-year to $1.43, while non-GAAP diluted EPS rose 35% year-over-year to $1.72 [1][10][13] Financial Guidance - The company raised its 2025 financial guidance ranges for total revenue to $1,300 - $1,375 million, representing year-over-year growth of 28% - 35% [1][11] - Adjusted EBITDA guidance was raised to $885 - $935 million, indicating year-over-year growth of 40% - 48% [1][11] - Non-GAAP diluted EPS guidance was increased to $6.10 - $6.50, reflecting year-over-year growth of 44% - 54% [1][11] Corporate Developments - The company announced a transition plan for its Chief Financial Officer, Nicole LaBrosse, who will remain in her position until a successor is found or until March 30, 2026 [2][5] - Halozyme is set to acquire Elektrofi, a biopharmaceutical company, for $750 million in upfront consideration, with additional milestone payments contingent upon product regulatory approvals [8][11] - The acquisition is expected to close in the fourth quarter of 2025, pending regulatory review [8][11] Product and Market Expansion - The company achieved two new indication approvals this quarter, enhancing its growth catalysts [3][4] - The continued success of ENHANZE-enabled therapies, including DARZALEX SC, Phesgo, and VYVGART Hytrulo, underscores the strength of Halozyme's royalty-driven business model [3][4] - The company anticipates revenue growth contributions from additional launched ENHANZE products to increase in 2026 and beyond [3][4]

Core Insights - Halozyme Therapeutics (HALO) is set to report its third-quarter 2025 results on November 3, with sales and earnings estimates at $336.9 million and $1.62 per share respectively [1][7] - Earnings estimates for 2025 have risen from $6.01 to $6.18 per share over the past 60 days [1] Earnings Performance - Halozyme has a strong history of earnings surprises, having exceeded earnings expectations in the last four quarters with an average surprise of 19.74% [2][3] - The most recent quarter saw an earnings surprise of 25.20% [2] Earnings Prediction Model - The company's earnings prediction model indicates a likely earnings beat, supported by a positive Earnings ESP of +2.53% and a Zacks Rank of 3 (Hold) [4][5] Revenue Drivers - The anticipated revenue for Q3 2025 is expected to be bolstered by royalty gains from partnerships with Roche, J&J, and argenx [7][9] - Halozyme's collaboration agreements with large pharmaceutical companies utilizing its ENHANZE technology are key revenue contributors, generating royalties, milestone payments, and annual license fees [8] Recent Developments - Halozyme has entered into an agreement to acquire Elektrofi for $750 million, which is expected to enhance its drug delivery technology and support long-term revenue growth [11][12] - The company reaffirmed its 2025 revenue guidance, expecting total revenues between $1.28 billion and $1.36 billion, with royalty revenues projected at $825-$860 million [13] Stock Performance and Valuation - Year-to-date, Halozyme's shares have increased by 38.4%, outperforming the industry and the S&P 500 [14] - The stock is currently trading at a price-to-sales ratio of 6.97, which is above the industry average of 2.26 but below its five-year mean of 8.41 [16] Financial Position - Halozyme maintains a strong financial position with $548 million in cash and no near-term debt, providing sufficient liquidity for operations [17] Growth Potential - The company is expected to benefit from higher royalties and incremental contributions from proprietary products, alongside the diversification from the Elektrofi acquisition [18] - Analysts have a positive outlook on the stock, reflected in rising earnings estimates [20]

Core Insights - Halozyme Therapeutics, Inc. will release its third quarter 2025 financial and operating results on November 3, 2025, after market close [1] - A conference call to discuss the results will be held on the same day at 1:30 p.m. PT/4:30 p.m. ET, accessible via pre-registration [2] Company Overview - Halozyme is a biopharmaceutical company focused on innovative solutions to enhance patient experiences and outcomes, particularly through its ENHANZE® drug delivery technology [3] - The company has impacted over one million patients through its technology, which is licensed to major pharmaceutical companies including Roche, Takeda, and Pfizer [3] - Halozyme also develops drug-device combination products aimed at improving convenience and patient adherence, with two proprietary products, Hylenex® and XYOSTED®, currently on the market [4] Recent Developments - Halozyme has announced a definitive agreement to acquire Elektrofi, Inc., which is expected to enhance its innovative drug delivery offerings and support long-term growth [8]

Core Insights - Halozyme Therapeutics (HALO) has established collaboration deals leveraging its ENHANZE technology with major pharmaceutical companies, generating royalties, milestone payments, and annual license fees that contribute to its revenue stream [1][2]. Group 1: Collaboration and Revenue Generation - Halozyme has eight marketed partnered drugs utilizing ENHANZE technology, including subcutaneous formulations of J&J's Darzalex and Roche's Phesgo, which significantly contribute to its revenue [2]. - The company is actively pursuing new partnerships to diversify and enhance growth, recently agreeing to acquire Elektrofi, a biopharmaceutical firm known for its microparticle technology [3][4]. Group 2: Elektrofi Acquisition Details - The acquisition of Elektrofi involves an upfront payment of $750 million, with potential milestone payments of up to $150 million based on regulatory approvals for three products, expected to close in Q4 2025 [4][5]. - The integration of Elektrofi's Hypercon technology is anticipated to broaden Halozyme's drug delivery capabilities and support long-term revenue growth through a licensing and royalty model, with royalty revenues expected to commence in 2030 [5]. Group 3: Financial Outlook - Halozyme has reaffirmed its 2025 revenue guidance, projecting total revenues between $1.28 billion and $1.36 billion, with royalty revenues expected to be in the range of $825 million to $860 million [6][8]. - Adjusted EBITDA is forecasted to be between $865 million and $915 million, with adjusted EPS anticipated to range from $6.00 to $6.40 in 2025 [6]. Group 4: Stock Performance and Valuation - Year-to-date, Halozyme's shares have increased by 38.1%, outperforming the industry average rise of 8.1% [7]. - The company's shares are currently trading at a price-to-sales (P/S) ratio of 6.95, which is significantly higher than the industry average of 2.23, although below its five-year mean of 8.80 [9]. Group 5: Earnings Estimates - The Zacks Consensus Estimate for 2025 EPS has slightly decreased from $6.22 to $6.18 over the past 60 days, while estimates for 2026 have increased from $7.15 to $7.58 [10].

Core Viewpoint - Halozyme Therapeutics is acquiring Elektrofi for up to $900 million to enhance its drug delivery technology portfolio, specifically adding microparticle capabilities [1] Group 1: Acquisition Details - The acquisition includes an upfront payment of $750 million and three milestone payments of $50 million each, contingent on the approval of three undisclosed products [1] - Halozyme's acquisition aims to expand its offerings in subcutaneous drug delivery technologies [4] Group 2: Technology and Benefits - Elektrofi's platform, Hypercon, allows for biologic concentrations up to five times higher than standard formulations, enabling high protein concentrations while maintaining subcutaneous administration [2] - The new auto-injector technology from Elektrofi can reduce injection volume for the same dosage, creating more opportunities for administration in healthcare settings and at home [3] Group 3: Market Position and Financial Performance - Halozyme's revenue grew by 22% to over $1 billion in 2024, driven by its Enhanze subcutaneous drug delivery technology [5] - The business models of both Halozyme and Elektrofi are similar, focusing on royalty revenue, with Elektrofi's patents extending into the 2040s, supporting long-term revenue growth [6] Group 4: Future Prospects - Halozyme expects that two of Elektrofi's partner products will enter clinical development by the end of 2026, with potential royalties starting as early as 2030 [7] - There is a potential of up to $275 million in development and commercial milestone payments linked to these two products, which include de-risked mechanisms of action that are already approved blockbusters [7]

Transaction Summary - Halozyme 将收购 Elektrofi，总交易额为 7.5 亿美元[15]，外加 1.5 亿美元的或有里程碑付款[15]。 - Elektrofi 的 Hypercon 技术可以将生物制剂浓度提高到比当前行业标准水溶液配方高 4-5 倍[9]。 - 该交易预计在 2025 年第四季度完成[15]，对中期非 GAAP 摊薄后每股收益的稀释小于 5%[15]。 - 收购 Elektrofi 将扩大 Halozyme 在创新药物递送技术方面的视野和广度[9]。 - 预计 Hypercon 配方产品的临床开发将于 2026 年底或更早开始[13]，并预计 2030 年开始贡献特许权使用费收入[14]。 Financial Performance and Guidance - Halozyme 重申了 2025 年全年指导范围[15]，总收入为 12.75 亿至 13.55 亿美元[57]，其中特许权使用费收入为 8.25 亿至 8.6 亿美元[57]。 - 预计调整后的 EBITDA 为 8.65 亿至 9.15 亿美元[57]，非 GAAP 摊薄后每股收益为 6.00 美元至 6.40 美元[57]。 - 预计 2026 财年的增量运营费用约为 5500 万美元[15]。 Technology and Growth - Halozyme 正在扩展其产品组合，包括 ENHANZE® 和 Hypercon 等专有技术[21, 22]。 - Hypercon 的知识产权将持续到 2040 年代[9]，支持长期收入增长[45]。 - Halozyme 预计将通过与现有和新的生物制药合作伙伴合作，扩大合作和收入机会[9]。