Core Insights - 22nd Century Group, Inc. is leading the nicotine harm reduction movement in the tobacco industry, focusing on helping smokers control their nicotine consumption [3][4] - The company will host investor meetings on September 9, 2025, during the HC Wainwright Conference in New York [1][2] Company Overview - 22nd Century Group has developed the VLN cigarette, which contains 95% less nicotine than traditional cigarettes, providing smokers with a familiar alternative to manage their nicotine intake [4][5] - The company utilizes proprietary non-GMO reduced nicotine tobacco blends, supported by patented technologies that regulate nicotine biosynthesis in tobacco plants, ensuring a full flavor experience with lower nicotine levels [5] Product Details - VLN cigarettes are designed to allow consumers to significantly reduce their nicotine consumption while still enjoying a combustible cigarette format [4] - The extensive patent portfolio of 22nd Century Group secures its position as the only provider of low nicotine combustible cigarettes in the United States and key international markets [5]

Core Viewpoint - 22nd Century Group, Inc. is leading the nicotine harm reduction movement in the tobacco industry, focusing on providing smokers with alternatives to manage their nicotine consumption effectively [3][4]. Group 1: Company Overview - 22nd Century Group, Inc. has been at the forefront of combating the harms of smoking due to nicotine addiction for 27 years [1]. - The company is set to present at the Emerging Growth Virtual Investor Conference on August 20, 2025, at 1:10 PM Eastern Time [1]. - The flagship product, VLN cigarettes, contains 95% less nicotine than traditional cigarettes, allowing smokers to significantly reduce their nicotine intake [4]. Group 2: Product Details - VLN cigarettes are designed to provide an authentic smoking experience while enabling smokers to take control of their nicotine consumption [4]. - The company utilizes proprietary non-GMO reduced nicotine tobacco blends, supported by patented technologies that regulate nicotine biosynthesis in tobacco plants [5]. - The extensive patent portfolio ensures that 22nd Century Group holds the only low nicotine combustible cigarette in the United States and key international markets [5].

Core Insights - 22nd Century Group, Inc. is expanding its VLN product line with new partner brands and increased state authorizations, positioning itself as a leader in tobacco harm reduction [1][3][2] - The company reported a decrease in net revenues for Q2 2025, with a focus on profitable growth through its branded products [5][9] Business Highlights - The company commenced shipments of Pinnacle VLN products to nearly 1,000 locations, with additional locations expected [1][5] - State authorizations for VLN products have significantly increased, with 44 states now allowing sales of VLN products and 30 states for partner VLN products [5][10] - The company is working on developing additional tobacco products to cater to users seeking lower nicotine options [3][10] Financial Performance - Net revenues for Q2 2025 were $4.1 million, down 48.6% from $7.9 million in Q2 2024 [9] - Operating loss increased to $3.0 million compared to $2.6 million in the previous quarter, while net loss remained stable at $3.3 million [5][9] - Adjusted EBITDA loss was $2.6 million, slightly worse than the loss of $2.3 million in the previous quarter [5][9] Product Line Developments - Cigarette net revenues decreased to $2.7 million from $5.0 million in Q1 2025, despite an increase in carton volumes to 594 thousand [10] - Filtered cigar net revenues increased to $1.3 million, reflecting stabilized volume from new contracts [10] - The company announced new branding for its VLN products and two new partner brand VLN product families, with initial shipments expected in Q3 2025 [10][12] Balance Sheet Overview - Total debt was approximately $3.9 million at the end of Q2 2025, with net debt reduced to $0.7 million [7][9] - Cash reserves stood at approximately $3.1 million, down from $4.4 million at the end of 2024 [7][25]

Core Viewpoint - 22nd Century Group, Inc. is set to discuss its second quarter results for 2025 during a webcast on August 14, 2025, highlighting its ongoing efforts in nicotine harm reduction and the introduction of its VLN® cigarette product [1][2]. Company Overview - 22nd Century Group is a leader in the nicotine harm reduction movement within the tobacco industry, focusing on enabling smokers to manage their nicotine consumption [4]. - The company has developed the VLN® cigarette, which contains 95% less nicotine than traditional cigarettes, providing smokers with a familiar alternative to help reduce their nicotine intake [5]. Product Details - The VLN® cigarette is designed to allow consumers to make informed choices regarding their nicotine consumption, potentially avoiding addictive levels altogether [5]. - The proprietary reduced nicotine tobacco blends are created using patented technologies that regulate nicotine biosynthesis in tobacco plants, ensuring full flavor and high yield while maintaining low nicotine levels [6]. Webcast Information - The webcast will feature Larry Firestone, CEO, and Dan Otto, CFO, who will review financial results and discuss the company's progress and plans for 2025 [2][3]. - The live and archived webcast will be available on the company's Investor Relations website [3].

Core Viewpoint - 22nd Century Group, Inc. is the only tobacco company authorized by the FDA to produce reduced nicotine content combustible cigarettes, specifically their VLN products, which align with the proposed FDA standard for nicotine yield [1][4]. Group 1: Public Health Impact - Smoking in the U.S. results in over 480,000 deaths and costs more than $600 billion annually, significantly reducing life expectancy by 10 years [2]. - The proposed FDA standard aims to limit nicotine in combusted tobacco products to less than 0.7mg per gram, addressing public health issues related to nicotine addiction [2][9]. Group 2: Industry Position and Product Offering - 22nd Century Group's VLN products contain 95% less nicotine than traditional cigarettes, providing smokers with a familiar alternative that allows for better control over nicotine consumption [6][7]. - The company has developed proprietary non-GMO reduced nicotine tobacco blends through patented technologies, ensuring they hold a unique position in the market with the only low nicotine combustible cigarette in the U.S. and key international markets [7]. Group 3: Support from Medical Community - The American Academy of Family Physicians, representing over 128,300 family physicians, supports the FDA's proposed nicotine yield standard, emphasizing its importance in combating tobacco dependence [3][9].

Core Insights - 22nd Century Group is expanding the availability of its VLN® reduced nicotine content products through partnerships with multiple tobacco brands, aiming to reduce smoking rates and related health harms [1][2][3] - The FDA's proposed Tobacco Product Standard for nicotine yield, which sets a maximum nicotine content of 0.7 mg per gram of tobacco, is driving interest in VLN products, which average 0.5 mg per gram [3][4][5] - The implementation of the FDA's proposal could prevent approximately 48 million youth and young adults from starting to smoke by the year 2100 [4][6] Company Overview - 22nd Century Group is recognized as a pioneering company in nicotine harm reduction, providing smokers with options to control their nicotine consumption [7][8] - The VLN® cigarette is designed to offer a familiar alternative for traditional smokers, containing 95% less nicotine than conventional cigarettes [8][9] - The company holds a comprehensive patent portfolio that ensures it has the only low nicotine combustible cigarette in the U.S. and critical international markets [9]

Core Insights - 22nd Century Group, Inc. is launching new Pinnacle VLN and moist snuff products in over 1,700 stores across 27 states, marking a significant expansion in its product offerings [1][2] - The new products include Pinnacle VLN Gold and Menthol VLN cigarettes, which are expected to begin sales in late summer and early fall of 2025 [2][4] - The company aims to leverage its established Pinnacle brand, which has a strong sales track record, to drive success in the new product categories [2][5] Product Launch Details - The launch includes four new Pinnacle SKUs, with two specifically in the low nicotine category [1] - The moist snuff products will feature straight and wintergreen flavors, expected to be available in the second half of 2025 [4] - The manufacturing of these products will utilize proprietary VLN tobacco strains and will be distributed through existing national-scale distribution agreements [5][6] Company Background - 22nd Century Group is recognized as a pioneering nicotine harm reduction company, focusing on enabling smokers to control their nicotine consumption [7] - The flagship VLN cigarette contains 95% less nicotine than traditional cigarettes, providing an alternative for smokers looking to reduce their nicotine intake [8][10] - The company operates a facility in Mocksville, North Carolina, with the capacity to produce over 45 million cartons of combustible tobacco products annually [9]

Summary of 22nd Century Group (XXII) Conference Call - May 21, 2025 Company Overview - **Company Name**: 22nd Century Group Inc. - **Ticker Symbol**: XXII - **Headquarters**: Mocksville, North Carolina - **Industry**: Tobacco, specifically focused on nicotine harm reduction - **Key Brands**: VLN, Smoker Friendly, Pinnacle Core Points and Arguments - **Nicotine Harm Reduction**: The company is a pioneer in the nicotine harm reduction space, offering products with significantly lower nicotine content, specifically the VLN brand which contains 95% less nicotine than standard cigarettes [3][11][41] - **FDA Compliance**: 22nd Century Group's VLN products are the only FDA-authorized low nicotine combustible cigarettes, aligning with the FDA's low nicotine mandate issued in January 2025 [5][34] - **Market Strategy**: The company aims to create a new low nicotine category (VLNC) to differentiate its products from traditional cigarettes, similar to how light beers are marketed [4][7] - **Growth Initiatives**: Plans to expand the VLN product line with new SKUs and partner brands, enhancing market penetration through existing retail relationships [6][18][22] - **Retail Presence**: Currently, the company has products in 5,100 retail stores across 26 states, with plans to expand to all 50 states [21][23] Financial Performance - **Debt Reduction**: The company has reduced its debt from over $20 million to $3.9 million, aiming for a debt-free status in the future [31][36] - **Operational Efficiency**: Operating expenses have decreased to under $2 million, with a target to reach breakeven by Q4 2025 [31][37] Market Dynamics - **Consumer Trends**: There is a growing awareness and demand for nicotine harm reduction products, with billions being spent on awareness campaigns [10][12] - **Competitive Landscape**: Traditional tobacco companies continue to focus on high-nicotine products, which creates a market opportunity for 22nd Century Group to position itself as a healthier alternative [42][43] Product Development - **R&D Focus**: The company is working on expanding its product offerings, including non-combustible low nicotine products and new tobacco strains through partnerships with research institutions [29][30] - **New Product Launch**: Smoker Friendly has introduced a natural cigarette product, Smoker Friendly Black Label, which is positioned as a cost-effective alternative to premium brands [25][27] Consumer Targeting - **Ideal Customers**: The target market includes smokers looking to reduce their nicotine dependence, such as pregnant women or those in restrictive work environments [45][46] Additional Insights - **Marketing Strategy**: The company is revamping its branding to make it more appealing and accessible to consumers, aiming to capture attention in retail environments [9][16][20] - **Long-term Vision**: The company is focused on establishing itself as a leader in the low nicotine category, with a commitment to consumer choice and health [8][34][41] This summary encapsulates the key points discussed during the conference call, highlighting the company's strategic direction, market positioning, and financial health.

Core Insights - 22nd Century Group, Inc. is focused on nicotine harm reduction and offers smokers choices regarding their nicotine consumption [3][4] - The company will present a corporate update at the Emerging Growth Conference on May 21, 2025, led by CEO Larry Firestone [1][2] Company Overview - 22nd Century Group is a pioneering company in the tobacco industry, enabling smokers to control their nicotine intake [3] - The flagship product, VLN cigarettes, contains 95% less nicotine than traditional cigarettes and aims to reduce overall nicotine consumption [4][6] Product and Technology - VLN cigarettes are designed to provide an authentic smoking experience while allowing smokers to make informed choices about nicotine levels [4] - The company utilizes patented technologies to create reduced nicotine tobacco blends, ensuring high flavor and yield with significantly lower nicotine content [6] Manufacturing Capabilities - The company operates a 60,000 square foot facility in Mocksville, North Carolina, capable of producing over 45 million cartons of combusted tobacco products annually, with room for expansion [5] - The facility also provides turnkey contract manufacturing for other tobacco brands both domestically and internationally [5]

Core Insights - 22nd Century Group, Inc. reported a significant sequential sales increase of approximately 50% in Q1 2025, driven by its growth strategy and new sales activities across various product categories [1][3][6] - The company is preparing for the launch of its first VLN partner brand shipments and has made regulatory filings for new products in all 50 states [1][6] - The financial results indicate a reduction in operating loss and net loss compared to the previous quarter, reflecting improved operational efficiency [6][10] Financial Performance - Net revenues for Q1 2025 reached $6.0 million, up from $4.0 million in Q4 2024, marking a 50% increase [6][10] - Gross profit improved to a loss of $(0.6) million from $(1.3) million, while operating expenses decreased to $2.0 million from $2.8 million [6][10] - The operating loss decreased to $(2.6) million from $(4.1) million, and net loss decreased to $(3.3) million from $(4.2) million [6][10] Product Developments - The company launched VLN Red, expanding its reduced nicotine content product line, which already includes VLN Gold and Green [6][12] - New partner branded VLN products are set to be launched, supported by marketing campaigns to enhance sales volumes [3][6] - Shipments of conventional products under a new agreement with Smoker Friendly have commenced, including the launch of Smoker Friendly Black Label cigarettes [6][12] Debt and Liquidity - As of the end of Q1 2025, the company reported net debt of $3.4 million, down from $4.6 million at the end of the previous quarter [6][12] - The company has successfully reduced its total debt by $3.7 million year-to-date while managing working capital needs [12][33]