WALTHAM, Mass., May 02, 2025 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced that, effective May 1, 2025, the company granted a non-qualified stock option to purchase 5,000 shares of its common stock to one new employee under Xilio Therapeutics’ 2022 Inducement Stock Incentive Plan. The stock options have an exercise price of $0.755 per share, ...

When it comes to shares of Tempus AI (TEM 0.31%), many may feel like they're standing on a dock watching the stock sail off to the horizon. It's understandable if you identify with this. After all, shares of Tempus AI, a healthcare-oriented artificial intelligence (AI) leader, have soared more than 54% year to date (as of this writing), while the S&P 500 has plunged over 5%.But there's no need to fret that you've missed the boat on Tempus AI stock. While its climb so far in 2025 is impressive, it's easy to ...

Company Overview - ALX Oncology Holdings Inc. is a clinical-stage biotechnology company focused on developing novel therapies for cancer treatment and improving patient survival [2] - The company's lead candidate, evorpacept, is positioned as a potential cornerstone therapy in immuno-oncology and is currently undergoing multiple clinical trials across various cancer indications [2] - ALX Oncology's second candidate, ALX2004, is an innovative EGFR-targeted antibody-drug conjugate expected to enter Phase 1 trials in mid-2025 [2] Financial Reporting - ALX Oncology plans to report its first quarter 2025 financial results on May 8, 2025, before the market opens [1] - The company will not hold a teleconference in conjunction with the financial results press release [1]

Core Insights - Coherus BioSciences, Inc. will be webcasting its participation in several upcoming conferences, providing access to presentations via its Investor Events section on the company website [1][2] - The company is a fully integrated commercial-stage innovative oncology firm with an approved PD-1 inhibitor, LOQTORZI®, and a promising pipeline of mid-stage clinical candidates targeting various cancers [4] - Coherus' immuno-oncology pipeline includes multiple antibody immunotherapy candidates aimed at enhancing immune responses against tumors, with ongoing studies for novel treatments [5] Company Overview - Coherus is focused on growing sales of LOQTORZI in nasopharyngeal carcinoma and advancing new indications in combination with pipeline candidates and partners [4] - The company has a robust immuno-oncology pipeline, including Casdozokitug, an IL-27 antagonistic antibody, and CHS-114, a selective anti-CCR8 antibody, both in various stages of clinical trials [5] Upcoming Events - Coherus will participate in the Citizens Life Science Conference on May 8, 2025, at 9:00 a.m. EDT [6] - The company will also present at the HCW BioConnect @ Nasdaq NYC 2025 on May 20, 2025, at 12:00 p.m. EDT [6] - Additional participation includes the TD Cowen 6th Annual Oncology Innovation Summit on May 27, 2025, and the Jefferies Global Healthcare Conference on June 4, 2025 [6]

WILMINGTON, Del., May 01, 2025 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (Prelude) (Nasdaq: PRLD), a clinical-stage precision oncology company, announced today that the Company will participate in the Citizens Life Sciences Conference taking place in New York on May 7, 2025. On Wednesday, May 7, 2025, at 11:00 a.m. ET, Kris Vaddi, Ph.D., Chief Executive Officer of Prelude, Jane Huang, M.D., President and Chief Medical Officer, and Peggy Scherle, Ph.D., Chief Scientific Officer will participate i ...

WILMINGTON, Del., May 01, 2025 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (Prelude) (Nasdaq: PRLD), a clinical-stage precision oncology company, announced today that the Company will participate in the Citizens Life Sciences Conference taking place in New York on May 7, 2025. On Wednesday, May 7, 2025, at 11:00 a.m. ET, Kris Vaddi, Ph.D., Chief Executive Officer of Prelude, Jane Huang, M.D., President and Chief Medical Officer, and Peggy Scherle, Ph.D., Chief Scientific Officer will participate i ...

OPKO Health (OPK) Q1 2025 Earnings Call April 30, 2025 04:30 PM ET Company Participants Yvonne Briggs - Investor Relations and Corporate Development ExecutivePhillip Frost - Chairman & CEOElias Zerhouni - President & Vice ChairmanAdam Logal - SVP & CFOJeffrey Cohen - MD - Equity ResearchBilly Smith - Equity ResearchMichael Petusky - Managing Director Conference Call Participants James Stamos - AnalystYi Chen - Managing Director & Senior AnalystEdward Tenthoff - Sr. Research AnalystYale Jen - Senior Managing ...

Immuno-Oncology Results from Research Collaboration with Léon Bérard Cancer Center Presented at AACR Annual Meeting 2025 New gene expression signature for cancer patients to predict clinical response to immune checkpoint. Potential of signature to enhance personalized treatment for patients, regardless of cancer type. NANTES, France – April 30, 2025, 7:30 a.m. CET - OSE Immunotherapeutics SA (ISIN: FR0012127173; Mnemo: OSE), a biotech company dedicated to developing first-in-class therapies in immuno-oncolo ...

Summary of Seagen (SGEN) FY Conference Call - April 29, 2025 Company Overview - **Company**: Seagen (SGEN) - **Industry**: Biotechnology, specifically focused on cancer therapies - **Products**: Three approved products - ADCETRIS, PADCEV, and DUKYSA [4][5] Key Points and Arguments Product Pipeline and Development - Seagen has a robust pipeline with approximately 12 to 14 products in clinical development, aiming to expand existing drugs into blockbuster status [6] - ADCETRIS has surpassed $1 billion in global sales, with expectations for PADCEV and TUKYSA to follow suit [6] - Upcoming drug, TB, is set to present full data at ESMO, targeting cervical cancer [5][61] Recent Collaborations - Seagen announced two deals with Merck, focusing on the drug LV, an antibody drug conjugate, and a commercial deal for TUKYSA [7][8] - The collaboration with Merck is based on mutual respect and successful past projects, particularly with PADCEV [9][10] Competitive Landscape - The triple-negative breast cancer segment is underserved, with a significant need for new therapies due to poor prognosis [13][14] - LV is being optimized for use in triple-negative and hormone-responsive breast cancer, with promising early results [16] Financial Position and Business Development - Seagen expects to have approximately $2.5 billion in capital available for development and expansion following the Merck deal [20][21] - Plans include developing more than a dozen products, expanding globally, and enhancing manufacturing capabilities [22][24] - The company is open to business development deals, including in-licensing and acquisitions, to bolster its pipeline [25][26] PADCEV Performance - PADCEV has achieved a 35% market share in the second-line treatment setting in the U.S. [30] - The drug is undergoing pivotal trials to expand its use in frontline settings, with promising data from combination therapies [34][36] Future Opportunities - Seagen is exploring various indications for PADCEV, including non-muscle invasive bladder cancer, with a focus on improving patient outcomes [40][46] - TUKYSA is positioned for label expansion in breast cancer and other HER2-expressing malignancies, with ongoing trials [50][57] Upcoming Data and Expectations - Full data for Tisotumab vedotin (TB) will be presented at ESMO, with expectations of strong anti-tumor activity in cervical cancer [59][61] Other Important Content - The company emphasizes the importance of optimizing dosing schedules for drug efficacy, as seen with PADCEV [15] - Seagen's commitment to thorough due diligence in potential deals is highlighted, ensuring that only promising opportunities are pursued [28] This summary encapsulates the key insights from the Seagen FY Conference Call, focusing on the company's strategic direction, product pipeline, collaborations, and market positioning.

Summary of Seagen (SGEN) Conference Call on April 29, 2025 Company and Industry Overview - **Company**: Seagen (SGEN) - **Industry**: Oncology and Pharmaceutical Collaborations Key Points and Arguments 1. **Collaboration with Merck**: Seagen announced two significant collaborations with Merck, focusing on the development and commercialization of ladiratuzumab vedotin (LV) and TUKYSA, with a 50-50 cost and profit sharing agreement for LV worldwide [5][6][7] 2. **Financial Terms**: Seagen will receive an upfront payment of $600 million for LV and $125 million for TUKSA, along with a $1 billion equity investment from Merck at $200 per share. The total potential payments across both collaborations could reach approximately $4.5 billion [5][6][8] 3. **Clinical Development**: LV is currently in Phase I and II trials for breast cancer and other solid tumors, showing promising antitumor activity. The focus is on optimizing dosing schedules, particularly weekly administration [8][9][10] 4. **TUKYSA Commercialization**: TUKYSA is approved in five countries for HER2 positive breast cancer and is expected to expand its market presence in Asia, the Middle East, and Latin America through Merck's established commercial capabilities [11][12][13] 5. **Strategic Benefits**: The collaboration with Merck is expected to enhance the development and commercialization of both drugs, leveraging Merck's expertise in solid tumor clinical development and its global commercial presence [6][7][10] 6. **Regulatory and Market Expansion**: Seagen is actively building its international capabilities, with over 100 staff in Europe to support TUKYSA's launch in Canada and Europe. The EMA is currently reviewing TUKYSA's EU marketing authorization application [12][13] 7. **Pipeline Development**: Seagen has a robust pipeline with over a dozen drugs in development, including ADCETRIS, PADCEV, and TUKYSA. The company aims to expand its commercial drug portfolio significantly [15][43][46] 8. **Future Collaborations**: Seagen is open to future collaborations and acquisitions, focusing on expanding its global footprint and enhancing its pipeline with innovative ADCs and other cancer therapies [28][90][92] Additional Important Content 1. **Risk Factors**: The call highlighted potential risks, including the ability to close Merck's equity investment and uncertainties related to pharmaceutical development and regulatory approval processes [3] 2. **Market Potential**: The collaboration is expected to address significant patient populations, particularly in breast and gastric cancers, with a focus on optimizing treatment regimens [104][105] 3. **No Standstill Provisions**: The agreement does not include any standstill provisions that would limit Merck's ability to increase its stake in Seagen in the future [51] 4. **Biomarker Development**: Seagen has developed a biomarker for LIV1, which is highly expressed in various solid tumors, allowing for broader treatment opportunities [67][68] This summary encapsulates the key discussions and strategic directions outlined during the conference call, emphasizing Seagen's collaborations, financial outlook, and future growth potential in the oncology sector.