Core Insights - Ant Group has applied for trademarks related to virtual assets and blockchain technology in Hong Kong, including "ANTCOIN" [1][2] - The applications cover online payments, electronic wallets, foreign exchange services, and stablecoins [2] - The trademark filings are seen as a strategic move to protect Ant Group's interests in the virtual asset sector [3] Company Developments - The ANTCOIN trademark application was submitted in June and is currently pending [1] - In July, Ant Group partnered with Circle to pilot USDC-based cross-border payments, integrating a regulated stablecoin into its payment infrastructure [5] - In September, Ant Digital Technologies launched a blockchain platform to tokenize energy assets in China, linking approximately $8 billion worth of infrastructure to on-chain systems [6] Industry Context - Major tech firms, including Ant Group, were reportedly ordered to suspend stablecoin initiatives in Hong Kong in October 2025 [4] - Traditional financial institutions globally are moving towards stablecoin adoption, with Japan's major banks planning to issue stablecoins and North Dakota announcing a state-backed stablecoin [7]

Core Insights - Zelle is expanding its $1 trillion US payments network internationally by leveraging stablecoins to enhance the speed and cost-effectiveness of international money transfers [1][2]. Group 1: Expansion Plans - Early Warning Services (EWS), the operator of Zelle, announced a new initiative to extend its payment system beyond US borders using stablecoin technology [2]. - The initiative aims to provide faster, more reliable, and less costly international money transfers, building on the success of Zelle's domestic operations [3][4]. Group 2: Market Context - The move is seen as Zelle's most ambitious step since its domestic launch in 2017, responding to consumer demand for cheaper and more efficient international money transfer options [4]. - Major US banks, including JPMorgan Chase, Wells Fargo, and Bank of America, support EWS, giving it a scale that few fintech firms can match [4]. Group 3: Unanswered Questions - The announcement raised critical questions, such as whether a unified stablecoin will be created or if individual banks will issue their own [6]. - Details regarding foreign banking partners involved in the international rollout were not disclosed, which is essential for understanding the extent of Zelle's global ambitions [6]. - The launch date of the project remains unknown, with further announcements expected soon [7]. Group 4: Skepticism and Challenges - Skeptics express concerns that Zelle's stablecoin expansion may follow a pattern of institutional signaling without substantial outcomes, citing the complexities of coordinating numerous financial institutions [7]. - Historical examples, such as Fnality, illustrate the challenges banking consortia face in turning blockchain initiatives into functional systems [8].

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Core Insights - Grayscale has launched the Grayscale® Stacks Trust (ticker: STCK), which is the first publicly quoted investment vehicle for Stacks (STX) in the U.S., now trading on OTCQB [1][2] - The Trust allows investors to buy and sell STCK through brokerage accounts, marking a significant step in Grayscale's strategy to transition private offerings to public investment products [2][3] - The Stacks network enhances Bitcoin's capabilities by enabling smart contracts and decentralized applications, which could help manage increased demand on the Bitcoin network [3] Company Overview - Grayscale is recognized as the largest digital asset-focused investment platform, with approximately $31 billion in assets under management (AUM) as of September 30, 2025 [4] - The company aims to provide investors with access to the digital economy through a range of innovative investment products [4] Product Details - STCK has been available to accredited investors since May 2024, and its public listing represents a milestone in expanding investor access to digital assets [2][3] - The Trust is designed to provide exposure to STX, the token of the Stacks network, which integrates Bitcoin with smart contract functionality [3] Market Context - The introduction of STCK is part of a broader trend to integrate Bitcoin with advanced blockchain technologies, enhancing its scalability and functionality [3] - As new decentralized applications and token standards emerge on Bitcoin's blockchain, Grayscale believes that Stacks can address challenges related to transaction throughput and costs while maintaining security [3]

Core Insights - Silo Pharma is preparing to submit an investigational new drug (IND) application for its lead candidate SPC-15, aimed at treating PTSD and stress-induced anxiety, with preparations expected to commence before year-end 2025 [1][2][8] - The company has launched a digital assets treasury strategy to enhance capital resources and participate in cryptocurrency growth, combining staking for yield with a hedged overlay to mitigate volatility [2][4] Biopharmaceutical Platform - SPC-15 is advancing through final preparations for the IND submission, with positive results from a large animal safety study supporting its formulation [4][5] - The company is finalizing a drug-device study for the microchip-based nasal spray system used in SPC-15 delivery and has completed a GLP-compliant toxicology study, with data expected in early 2026 [5][8] - Silo is expanding its global intellectual property portfolio for SPC-15 technology, securing patents in the U.S., Australia, and Japan [5] Digital Assets Treasury - Initial cryptocurrency purchases have been made in Bitcoin, Ethereum, Solana, and ResearchCoin, with a focus on multi-chain digital asset growth and DeFi integration [5][6] - A new Crypto Advisory Board has been formed to enhance support for cryptocurrency audit and compliance, with additional members expected to join soon [5][6] - The company has engaged Fireblocks for secure institutional-grade infrastructure and custody technology services for its crypto treasury platform [5][6] Future Outlook - Significant milestones are anticipated in both drug development and digital asset purchases, positioning Silo to capitalize on emerging opportunities [6] - The company plans to pursue additional therapeutic indications for SPC-15 and secure the FDA's 505(b)(2) accelerated regulatory pathway for clinical development [8]

Core Insights - CleanCore Solutions, Inc. has established partnerships with U.S. Triestina 1918 and HC Sierre Hockey Club, marking a strategic move to integrate Dogecoin into global sports and everyday payments [1][2] - The investments aim to connect digital assets with sports, allowing fans to use Dogecoin for tickets, concessions, and merchandise, thereby enhancing fan experiences and promoting community ownership [2][3] - The Official Dogecoin Treasury, backed by CleanCore and the Dogecoin Foundation, is designed to provide stability and transparency to the Dogecoin ecosystem, facilitating institutional participation and real-world use cases for Dogecoin [3][5] Company Overview - CleanCore Solutions, Inc. focuses on revolutionizing cleaning practices through patented aqueous ozone technology, aiming for sustainable and cost-effective solutions [4] - House of Doge, the corporate arm of the Dogecoin Foundation, is dedicated to advancing Dogecoin as a decentralized global currency, investing in infrastructure for everyday commerce and developing financial products [5]

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Financial Highlights - Galaxy achieved a Q3 2025 Net Income of $505 million[18] - The company's Q3 2025 Adjusted Gross Profit reached $728 million[18] - Galaxy reported a Q3 2025 Adjusted EBITDA of $629 million[18] - The company holds $17 billion in Digital Assets on Platform[18] Digital Asset Ecosystem - Galaxy supports trading of over 100 unique crypto assets[41] - Staked Assets amount to $6.6 billion[48] - ETFs/ETPs total $3.9 billion[48] - Alternatives represent $4.9 billion[48] Data Center Infrastructure - Helios Data Center Campus has 800 MW of approved and committed power capacity[70] - An additional 2,700 MW of load capacity is under study[70] - The company anticipates over $1 billion in average annual revenue for combined phases of the Helios Data Center[71, 72]

Core Insights - Ethereum is the second-largest cryptocurrency by market capitalization, serving as a decentralized computing platform that supports smart contracts, decentralized applications, and tokenized assets [1][2] - It plays a crucial role in the web3 ecosystem, underpinning various applications from NFTs to stablecoins, making it a versatile and influential network in the crypto space [1][3] Ethereum's Functionality - Ethereum operates as a global, decentralized computer, enabling developers to create applications and execute digital agreements without centralized authorities, facilitating secure and automatic transactions of money, assets, and information [2] - The platform is the backbone of the modern crypto economy, powering decentralized finance (DeFi) platforms that allow users to lend, borrow, and earn interest without traditional intermediaries [3] Network Efficiency and Sustainability - The transition to a proof-of-stake consensus mechanism has significantly reduced Ethereum's energy consumption, creating a greener ecosystem that attracts environmentally conscious and income-seeking investors [4] Price Forecast and Market Potential - Analyst Geoff Kendrick from Standard Chartered predicts Ethereum could reach $25,000 by 2028, indicating a potential gain of over 540% from current levels as of October 18 [6] - The increasing adoption of stablecoins, which are pegged to assets like the U.S. dollar, positions Ethereum as the default settlement layer, likely boosting demand for its infrastructure [7] Regulatory Landscape - The regulatory environment is becoming more favorable, with expectations that Ethereum ETFs will follow the approval of Bitcoin ETFs, potentially unlocking new capital and solidifying Ethereum's status as a legitimate asset [9]

As filed with the United States Securities and Exchange Commission on October 20, 2025. TABLE OF CONTENTS Registration No. 333-289815 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Pre-Effective Amendment No. 2 to FORM S-1 (Address of principal executive offices) (I.R.S. Employer Identification No.) 95816 (Zip Code) (818) 683-2765 (Registrant's telephone number, including area code) (Exact name of registrant as specified in its charter) (State or other jurisdiction of Alberta, Canad ...