Core Insights - Enlivex has implemented the world's first RAIN prediction markets token digital asset treasury strategy through RAIN token accumulation [1][3][7] - The company is focused on the clinical development of Allocetra, a novel therapy for knee osteoarthritis, addressing a significant unmet medical need in a growing market [2][8] Company Developments - Enlivex has closed a $212 million private investment, with plans to utilize the proceeds for the RAIN prediction markets token treasury strategy while maintaining its core business operations [3][7] - Former Italian Prime Minister Matteo Renzi has joined the Board of Directors, emphasizing the importance of responsible innovation and the potential of blockchain technologies [5] RAIN Protocol Overview - RAIN is a decentralized predictions and options protocol built on the Arbitrum network, allowing users to create and trade custom options on various markets [4] - The protocol features a deflationary Buyback & Burn mechanism and aims to be a leading platform for prediction markets, promoting transparency and community participation [4] Market Context - Osteoarthritis affects over 32.5 million Americans and more than 300 million people globally, with a projected increase to 78 million Americans by 2040 [8] - There are currently no FDA or EMA approved medications that can effectively halt or reverse the progression of joint damage in osteoarthritis patients, highlighting a critical need for effective treatments [8]

Core Insights - IP Strategy is the first Nasdaq-listed company to operate a digital asset treasury strategy centered on the $IP token, providing investors with exposure to the programmable intellectual property economy valued at $80 trillion [3] - The company held its inaugural Investor Day 2025, where it discussed its growth strategy and the convergence of AI, blockchain, and intellectual property [2][3] - Story, the blockchain network supporting the $IP token, has received $136 million in backing and launched its mainnet in February 2025, enabling the monetization of intellectual property in real time [5] Company Overview - IP Strategy operates a revenue-generating validator for the Story network and holds $IP tokens as a primary reserve asset [3] - The company aims to provide public market investors with a regulated equity format to participate in the Story ecosystem, which facilitates on-chain registration, licensing, and monetization of intellectual property [3] Industry Context - The Story network is described as an AI-native blockchain that makes intellectual property programmable and traceable, allowing creators to turn various forms of content into legally enforceable digital assets [5] - The convergence of AI, blockchain, and intellectual property is seen as a significant trend shaping a new investable asset class [2]

Table of Contents As filed with the Securities and Exchange Commission on October 29, 2025. Registration Statement No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Applied DNA Sciences, Inc. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) (Primary Standard Industrial Classification Code Number) 50 Health Sciences Drive Stony Brook, New York 11 ...

Core Insights - Qualigen Therapeutics Inc. has announced a strategic partnership with BitGo to support its C10 treasury strategy, which aims to accumulate a market-cap-weighted basket of the world's top 10 crypto assets, excluding stablecoins [1][4]. Group 1: Partnership Details - The partnership will allow Qualigen to utilize BitGo's comprehensive treasury management services, which include access to deep liquidity and secure custody solutions [2][3]. - BitGo's OTC desk will facilitate efficient investments across a diversified basket of 10 digital assets, marking a significant advancement in Qualigen's treasury strategy [2][4]. Group 2: Security and Compliance - Qualigen's treasury assets will be stored securely in regulated cold storage by BitGo, adhering to high security standards and compliance protocols [3][4]. - BitGo's expertise in digital assets will simplify the complexities associated with institutional digital asset adoption, enabling Qualigen to focus on sustainable growth and digital integration [3][4]. Group 3: Strategic Vision - The partnership reflects Qualigen's commitment to financial resilience and leadership in the evolving digital economy, as stated by Co-CEO Jerry Wang [4]. - The $30 million multi-asset allocation signifies growing enterprise confidence in adopting a digital-first treasury strategy [4].

Core Viewpoint - Cemtrex Inc. has initiated a digital asset treasury strategy by acquiring approximately $1 million worth of Solana (SOL) and aims to expand its crypto reserves to $10 million over time [1][2]. Group 1: Acquisition and Strategy - The company purchased 5,500 SOL at an average cost of approximately $181 per token, with plans to stake its position for on-chain yield and operate its own validator node [2]. - Cemtrex's long-term goal is to build a $10 million reserve position across strategic crypto networks, with Solana as the foundational asset [2][4]. Group 2: Solana's Performance and Positioning - Solana is currently processing over 1,000 transactions per second and handled more than 90 billion transactions in June 2025, outperforming all other layer-one and layer-two blockchains combined [3]. - The blockchain features a burn mechanism tied to usage and a hardcoded inflation schedule that will bottom out at 1.5% by 2028, positioning it as a foundational layer for digital trust and settlement [3]. Group 3: Long-term Vision - The acquisition is described as a long-duration bet on Solana, which is viewed as the most capable and capital-efficient blockchain system, expected to compound its network advantage faster than the market anticipates [4][5]. - Cemtrex is exploring the integration of blockchain technologies into its product lines, including cryptographic video authentication and decentralized timestamping through its subsidiary, Vicon [4].

Core Viewpoint - Liminatus Pharma, Inc. has engaged Digital Offering LLC as its exclusive placement agent to explore innovative treasury-backed financing options to strengthen its capital structure [1][2][4] Group 1: Engagement and Strategy - The engagement with Digital Offering supports Liminatus's review of a digital asset treasury strategy, evaluating modern financial tools for capital structure enhancement [2][4] - The potential funding initiative may involve various exempt financing structures, including convertible debentures and equity-linked securities, compliant with U.S. securities laws [2][4] Group 2: Role of Digital Offering - Digital Offering is tasked with sourcing institutional and digital asset-focused investors and structuring a compliant financing solution for Liminatus [3][4] - The partnership aims to explore strategic funding opportunities in both traditional markets and the evolving digital asset landscape [4] Group 3: Company Overview - Liminatus is a preclinical-stage biopharmaceutical company focused on developing targeted cancer immunotherapies, advancing a pipeline of novel therapies [6] - The company is committed to responsible innovation in its capital strategy to support long-term scientific and operational objectives [6]

Core Insights - BTCS Inc. has acquired 1,000 Ether (ETH) for approximately $2.63 million, increasing its total ETH holdings to about 13,500 ETH, which represents a 50% increase from 9,063 ETH at the end of Q1 2025 [1][2]. Company Strategy - The CEO of BTCS emphasized that the expanding ETH position is part of a broader strategy focused on building scalable, revenue-generating blockchain infrastructure rather than merely a treasury strategy [2]. - BTCS aims to maximize strategic value from every ETH purchase by utilizing Crypto.com's institutional offering, which helps reduce slippage and optimize capital deployment across blockchain initiatives [2]. Partnership with Crypto.com - Crypto.com Exchange, launched in the U.S. in 2024, provides advanced trading capabilities with deep global liquidity and ultra-low latency, catering to institutional and advanced clients [2][3]. - The partnership with Crypto.com is intended to enhance BTCS's cryptocurrency acquisition strategy and support its ongoing crypto reserve journey [3]. Company Overview - BTCS Inc. is focused on driving scalable revenue growth through blockchain infrastructure operations, specializing in block building and validator node management [3]. - The company operates a branded block-building operation called Builder+, which optimizes block construction for on-chain validation to maximize gas fee revenues [3]. - BTCS has developed ChainQ, an AI-powered blockchain data analytics platform, to enhance user access and engagement within the blockchain ecosystem [3].

Core Viewpoint - Janover Inc. has adopted a digital asset treasury strategy, focusing on accumulating Solana (SOL) as a key asset, reflecting a commitment to capital deployment in favorable market conditions [1][2][3] Group 1: Treasury Strategy - The Board of Directors approved a new treasury policy on April 4, 2025, allowing for long-term accumulation of cryptoassets, starting with Solana [2] - Janover intends to operate one or more Solana validators to stake its treasury assets, securing the network and earning rewards for reinvestment [2][3] Group 2: Current Holdings and Financial Metrics - As of April 15, 2025, Janover holds a total of 163,651.7 SOL, valued at approximately $21.2 million, including staking rewards [1][7] - The recent purchase of 80,567 SOL was valued at about $10.5 million, marking the third execution under the new treasury strategy [1] - The total shares outstanding are approximately 1.5 million, resulting in a SOL per share (SPS) of 0.11, valued at $14.47 per share, with a 120% growth in SPS compared to the last purchase [7]

Core Viewpoint - Janover, Inc. has successfully raised approximately $42 million through a private offering of convertible notes and warrants, aimed at accelerating its acquisition of digital assets, particularly within the Solana ecosystem [1][3]. Group 1: Offering Details - The aggregate principal amount of the convertible notes sold was approximately $42 million, with an interest rate of 2.5% per year, maturing on April 6, 2030 [2]. - The notes are convertible into common stock, contingent upon the company's market capitalization reaching or exceeding $100 million prior to conversion, with a minimum conversion price set at $4.81 [2]. - For every $1,000 in principal amount of convertible notes purchased, warrants were issued to purchase approximately 8.333 shares at an exercise price of $120 per share and approximately 6.666 shares at an exercise price of $150 per share [2]. Group 2: Company Strategy - The proceeds from the offering are intended to enhance the company's efforts in acquiring digital assets, starting with the Solana ecosystem through the US public markets [3]. - The company has adopted a treasury policy that allocates its principal holding in treasury reserves to crypto assets, beginning with Solana (SOL), to provide investors with economic exposure to SOL investment [7]. Group 3: Company Overview - Janover Inc. operates as an AI-powered online platform that connects the commercial real estate industry, offering data and software subscriptions along with value-added services [5]. - The company serves over one million web users annually, including property owners, developers, and various lenders, facilitating billions of dollars in debt financing each year [6].