Group 1 - The State Intellectual Property Office of China shows that Komei Diagnostic Technology Co., Ltd. and Komei Boyang Diagnostic Technology (Shanghai) Co., Ltd. have applied for a patent titled "Preparation Method and Application of Biotin-Labeled Small Molecules," with publication number CN120214293A and application date of December 2023 [1] - The patent involves a method for preparing biotin-labeled small molecules, which includes mixing small molecules with an activator to obtain activated small molecule reagents, where the molecular weight of the small molecules is less than 1000 Da, and then reacting the activated small molecule reagents with biotin-labeled marker reagents, where the molecular weight of the biotin-labeled markers is between 1000 Da and 10000 Da [1] - Komei Diagnostic Technology Co., Ltd. was established in 2007 in Beijing, focusing on professional technical services, with a registered capital of 401.108 million RMB, and has invested in 3 companies, participated in 74 bidding projects, and holds 475 patents [1] Group 2 - Komei Boyang Diagnostic Technology (Shanghai) Co., Ltd. was established in 2005 in Shanghai, primarily engaged in pharmaceutical manufacturing, with a registered capital of 34.088364 million RMB, and has invested in 1 company, participated in 87 bidding projects, and holds 315 patents [2] - The company has 36 trademark registrations and 126 administrative licenses [2]