Core Viewpoint - French scientists have developed a groundbreaking ultrasound imaging technology that enables comprehensive and high-precision visualization of microcirculation and blood flow dynamics in major organs, providing unprecedented insights for the research and diagnosis of blood circulation-related diseases [1][3]. Group 1: Technology Development - The new ultrasound probe allows for four-dimensional blood flow imaging in live animal models, achieving spatial resolution below 100 micrometers, which is sufficient to capture blood flow changes in the smallest blood vessels [3][4]. - This technology can visualize the entire vascular network of organs and accurately quantify blood flow dynamics, distinguishing between arterial, portal, and hepatic venous systems in the liver [3][4]. Group 2: Clinical Application - The technology is currently entering clinical testing, with efforts to integrate the device into human applications, as the probe can connect to a small portable device [4]. - Once applied clinically, this technology is expected to become a vital tool for understanding systemic hemodynamics, covering all levels from the aorta to pre-capillary arterioles, and providing objective evidence for monitoring small vessel-related diseases [4].