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基因变异与心血管风险
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新研究有望推动心血管疾病个性化预防
Xin Hua Wang· 2025-10-27 03:10
Core Insights - An international research team has identified specific gene variations closely associated with high-risk groups for cardiovascular events, which may enhance early screening and personalized prevention of cardiovascular diseases [1][2] Group 1: Research Findings - The study reveals that atherosclerosis, a chronic cardiovascular disease characterized by thickening and hardening of blood vessel walls due to lipid deposits, is often undetected until severe events like myocardial infarction or stroke occur [1] - Researchers have categorized populations into four distinct risk levels for atherosclerosis, with varying probabilities of experiencing cardiovascular events [1] - A particular variant of the IL6R gene has been identified as significantly increasing the likelihood of myocardial infarction in high-risk groups, despite having limited impact on the general population [1] Group 2: Implications for Treatment - Identifying these genetic markers is crucial for developing personalized intervention strategies, allowing for early intervention during asymptomatic stages to potentially halt or reverse the progression of atherosclerosis [2] - The research has been published in the international journal "Cardiovascular Research," and future evaluations will focus on whether drugs targeting the IL6R gene pathway can reverse rapid atherosclerosis progression in specific populations [2]